Unreviewed, UniProtKB/TrEMBL Q9VX92 (Q9VX92_DROME)

Names and origin

Protein names

Submitted name:
    RhoGAP15B, isoform C EMBL AAF48686.3

Gene names

Name:	RhoGAP15B EMBL AAF48686.3 FlyBase FBgn0030808
ORF Names:	Dmel_CG4937 EMBL AAF48686.3

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1552 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 PH domain. Spearmint SPM000198 Contains 1 Rho-GAP domain. Spearmint SPM000198

Ontologies

Keywords
Molecular function	GTPase activation Spearmint SPM000198
Gene Ontology (GO)
None. [Check GOA]

Sequences

	Sequence		Length	Mass (Da)
	Q9VX92-1 [UniParc]. Last modified March 3, 2009. Version 3. Checksum: BEC8BF0525BAA96D	FASTA	1,552	174,299
	10 20 30 40 50 60 MEQARPVPAP RRLYPELRPA NYENIEIRRP NSPSNNINHN NIKKLNINAE NLHGNCAEKK 70 80 90 100 110 120 LPSSGQNKLI LQENNSDSQQ PIYGPDANEN VQEPVYATPR PAPRQRLPPA GEPEDSYPDP 130 140 150 160 170 180 DDEVPLRILR AAPQIPPKPL NILLDQRSSI CSEVSTTSVQ TPGKADEDRE GSRYASNASL 190 200 210 220 230 240 DCSESSHSGK FKSQSPGYVD AVDSSIPQSD HPDPNGHHPQ AESSSAEQSS GSQDGDDDNN 250 260 270 280 290 300 LLRSLGTTSK LLGEAIGERI TFKAKGAKKR LDRNFKSSTE AISNIGADAG RSLKHASKRF 310 320 330 340 350 360 GSNFSLGRNK DKADIGIGGR PGGSGEMDLD RRQTMPSTEV FNTIQFSSPL NRNGGLPDLR 370 380 390 400 410 420 ENDAKLQKED YLRPDPDQED DGCYEVPKTQ GKPPSYDEAL RSRPSPSDSP MSRNLAQEAA 430 440 450 460 470 480 QLVQLRNQRQ LSSSSSNGDE SPRLPMPAFP PPRLSQQPEQ FRMDALQPPV RQKRRKNYEH 490 500 510 520 530 540 IELRRPPVDS AQLEELNRAA AAAEREESLL ISAKNAEAET KTPKPERSDS WEFYGEDENE 550 560 570 580 590 600 EEDRDEEQEG SSSPEPLYAN QEATYGKLFE MATAGSSRSN VLTPNQVAEQ QQLACITEDS 610 620 630 640 650 660 ELDACEGAVG GVPLPQAVIE EFDPLSSKCS TLARSNKSNE LLLLEHLLEE DTYGTVKAEQ 670 680 690 700 710 720 DDVSMCTSEE EPTTSAATSP KPQQPQIVHQ NARLLSDSME NMLDSDQERA KPYLSRMPES 730 740 750 760 770 780 ANKASGPVDL ASASRNRTNW FVPDKASCSD VTPNTSKTTP PIEGDSPPTY LEAIGGSKDA 790 800 810 820 830 840 AGNQENRSTI GSRFRQTINA ISNVKLKMDA MKRKASFRGA NQRQSDVRVA LQMVPRPSLS 850 860 870 880 890 900 PLLIRYEGPL VRFPSGVVED ILKEMQNRKA ILRERQFQTF LDQEMKTPRE MIPLDTITTL 910 920 930 940 950 960 QCVSNSRVTD TATHFYCFEI TTSQPKNGNG AGDAMSSNPN LLMTSSSSGN VKQQRVSHLY 970 980 990 1000 1010 1020 GVGKESERGV WMQKILESLT NSLPVKYTCH YYRAGWCYLK NSITSEWSGT WLVLRKSQRR 1030 1040 1050 1060 1070 1080 LIFVSEANGN VEKMDLRKAR CIVLKESDES IDNLHVESGP MLMIDCPPYA VYMIMSSARE 1090 1100 1110 1120 1130 1140 TKIWRHIIRE VAHNNGFSLG DQQLTRYDVP VIVDKCINFV YIHGSMSEGI YRKSGSENSM 1150 1160 1170 1180 1190 1200 HKLMSAFRAD AFNVEITRNE YNEHDVANVL KRFMRDLPER LLGKLTDSFV FVTELAVASE 1210 1220 1230 1240 1250 1260 KIPIYRELLA RLSAIERETL RRIVGHLVFI SSQQAKNKMS VQNLTMIWGP TLLAKKSDEL 1270 1280 1290 1300 1310 1320 IYSQKEADVL SDLVVLYKNL FPCSADEIKR EQAMLACLQK YYAAAETLKD AVKQSGDIKI 1330 1340 1350 1360 1370 1380 WISLNPNPEN KTEEKTQVNA TISPTKTAYE LCREYSAKMQ LPTHQLTLYE VILNDSLERP 1390 1400 1410 1420 1430 1440 LHHDTKVFDV ILNWSYWPEE DRKHNYLVVR PVEMLREIQR AVKNLATVTP GKELRFADSR 1450 1460 1470 1480 1490 1500 TKTFKTLQCE LRDGKIVVSK KDKNDKTTIV REIFLQSSTA YLGCERKRDF PWSWAITFVE 1510 1520 1530 1540 1550 RTQAQIMRSR DAPFIGHVLA GSEWGDRTIW YSSIWYCLYR DNILPPAEII IK

References

[1]

"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.

[2]

"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014298 Genomic DNA. Translation: AAF48686.3.
RefSeq	NP_573183.2.
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	FBgn0030808. Drosophila melanogaster. [Contig view]
GeneID	32686.
Organism-specific databases
FlyBase	FBgn0030808. RhoGAP15B.
Gene expression databases
ArrayExpress	Q9VX92.
Family and domain databases
InterPro	IPR001849. Pleckstrin_homology. IPR000198. RhoGAP. [Graphical view]
Gene3D	G3DSA:1.10.555.10. RhoGAP. 1 hit.
Pfam	PF00620. RhoGAP. 1 hit. [Graphical view]
SMART	SM00233. PH. 2 hits. SM00324. RhoGAP. 1 hit. [Graphical view]
PROSITE	PS50238. RHOGAP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9VX92_DROME

Accession

Primary (citable) accession number: Q9VX92

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	March 3, 2009
Last modified:	July 7, 2009
This is version 57 of the entry and version 3 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)