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Protein
Submitted name:

CG8142

Gene

CG8142

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • DNA-dependent DNA replication Source: GO_Central
  • DNA repair Source: GO_Central
  • lateral inhibition Source: FlyBase

Enzyme and pathway databases

ReactomeiR-DME-110312. Translesion synthesis by REV1.
R-DME-110314. Recognition of DNA damage by PCNA-containing replication complex.
R-DME-110320. Translesion Synthesis by POLH.
R-DME-174411. Polymerase switching on the C-strand of the telomere.
R-DME-176187. Activation of ATR in response to replication stress.
R-DME-5651801. PCNA-Dependent Long Patch Base Excision Repair.
R-DME-5655862. Translesion synthesis by POLK.
R-DME-5656121. Translesion synthesis by POLI.
R-DME-5656169. Termination of translesion DNA synthesis.
R-DME-5696397. Gap-filling DNA repair synthesis and ligation in GG-NER.
R-DME-6782135. Dual incision in TC-NER.
R-DME-6782210. Gap-filling DNA repair synthesis and ligation in TC-NER.
R-DME-69091. Polymerase switching.

Names & Taxonomyi

Protein namesi
Submitted name:
CG8142Imported
Submitted name:
LD35209pImported
Gene namesi
ORF Names:CG8142Imported, Dmel_CG8142Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0030871. CG8142.

Subcellular locationi

GO - Cellular componenti

  • DNA replication factor C complex Source: GO_Central
  • Elg1 RFC-like complex Source: FlyBase
  • nucleus Source: GO_Central

Expressioni

Gene expression databases

BgeeiFBgn0030871.

Interactioni

Protein-protein interaction databases

IntActiQ9VX15. 4 interactors.
MINTiMINT-847740.
STRINGi7227.FBpp0074246.

Structurei

3D structure databases

SMRiQ9VX15.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 193AAAInterPro annotationAdd BLAST132

Phylogenomic databases

eggNOGiKOG0989. Eukaryota.
COG0470. LUCA.
GeneTreeiENSGT00550000074917.
KOiK10755.
OMAiEADSMTH.
OrthoDBiEOG091G0CKT.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR008921. DNA_pol3_clamp-load_cplx_C.
IPR027417. P-loop_NTPase.
IPR013748. Rep_factorC_C.
PfamiView protein in Pfam
PF00004. AAA. 1 hit.
PF08542. Rep_fac_C. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SUPFAMiSSF48019. SSF48019. 1 hit.
SSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9VX15-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQAFLKTGKS TAGSGDKSQG TPAARRKPPA PWVEKYRPRN VDDVVEQSEV
60 70 80 90 100
VAVLRKCVEG GDLPNMLLYG PPGTGKTSTI LAASRQIFGD MFKDRILELN
110 120 130 140 150
ASDERGINVV RTKIKNFSQL SASSVRPDGK PCPPFKIIIL DEADSMTHAA
160 170 180 190 200
QSALRRTMEK ESRSTRFCLI CNYVSRIIVP ITSRCSKFRF KALGEDKVID
210 220 230 240 250
RLKYICEMEG VKIEDDAYKS IVKISGGDLR RAITTLQSCY RLKGPEHIIN
260 270 280 290 300
TADLFEMSGV IPEYYLEDYL EVCRSGNYER LEQFVREIGF SAYSVGQMME
310 320 330 340 350
QFVEFIVHHP GLNDPQKATI CDKLGECCFR LQDGGSEYLQ IMDLGCCIIL

ALK
Length:353
Mass (Da):39,555
Last modified:October 1, 2002 - v2
Checksum:i97F2516D7BCA33D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF48768.2.
AY069598 mRNA. Translation: AAL39743.1.
RefSeqiNP_573245.1. NM_133017.4.
UniGeneiDm.2050.

Genome annotation databases

EnsemblMetazoaiFBtr0074472; FBpp0074246; FBgn0030871.
GeneIDi32763.
KEGGidme:Dmel_CG8142.
UCSCiCG8142-RA. d. melanogaster.

Similar proteinsi

Entry informationi

Entry nameiQ9VX15_DROME
AccessioniPrimary (citable) accession number: Q9VX15
Secondary accession number(s): Q8T033
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: October 1, 2002
Last modified: August 30, 2017
This is version 156 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported