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Protein
Submitted name:

CG8142

Gene

CG8142

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cytoplasmic microtubule organization Source: FlyBase
  • DNA-dependent DNA replication Source: GO_Central
  • lateral inhibition Source: FlyBase

Enzyme and pathway databases

ReactomeiR-DME-110312. Translesion synthesis by REV1.
R-DME-110314. Recognition of DNA damage by PCNA-containing replication complex.
R-DME-110320. Translesion Synthesis by POLH.
R-DME-174411. Polymerase switching on the C-strand of the telomere.
R-DME-176187. Activation of ATR in response to replication stress.
R-DME-5651801. PCNA-Dependent Long Patch Base Excision Repair.
R-DME-5655862. Translesion synthesis by POLK.
R-DME-5656121. Translesion synthesis by POLI.
R-DME-5656169. Termination of translesion DNA synthesis.
R-DME-5696397. Gap-filling DNA repair synthesis and ligation in GG-NER.
R-DME-6782135. Dual incision in TC-NER.
R-DME-6782210. Gap-filling DNA repair synthesis and ligation in TC-NER.
R-DME-69091. Polymerase switching.

Names & Taxonomyi

Protein namesi
Submitted name:
CG8142Imported
Submitted name:
LD35209pImported
Gene namesi
ORF Names:CG8142Imported, Dmel_CG8142Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0030871. CG8142.

Subcellular locationi

GO - Cellular componenti

  • DNA replication factor C complex Source: GO_Central
  • Elg1 RFC-like complex Source: FlyBase
  • microtubule associated complex Source: FlyBase

Expressioni

Gene expression databases

BgeeiFBgn0030871.

Interactioni

Protein-protein interaction databases

MINTiMINT-847740.
STRINGi7227.FBpp0074246.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 193AAAInterPro annotationAdd BLAST132

Phylogenomic databases

eggNOGiKOG0989. Eukaryota.
COG0470. LUCA.
GeneTreeiENSGT00550000074917.
KOiK10755.
OMAiRQIFGDM.
OrthoDBiEOG091G0CKT.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR008921. DNA_pol3_clamp-load_cplx_C.
IPR027417. P-loop_NTPase.
IPR013748. Rep_factorC_C.
PfamiView protein in Pfam
PF00004. AAA. 1 hit.
PF08542. Rep_fac_C. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SUPFAMiSSF48019. SSF48019. 1 hit.
SSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9VX15-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQAFLKTGKS TAGSGDKSQG TPAARRKPPA PWVEKYRPRN VDDVVEQSEV
60 70 80 90 100
VAVLRKCVEG GDLPNMLLYG PPGTGKTSTI LAASRQIFGD MFKDRILELN
110 120 130 140 150
ASDERGINVV RTKIKNFSQL SASSVRPDGK PCPPFKIIIL DEADSMTHAA
160 170 180 190 200
QSALRRTMEK ESRSTRFCLI CNYVSRIIVP ITSRCSKFRF KALGEDKVID
210 220 230 240 250
RLKYICEMEG VKIEDDAYKS IVKISGGDLR RAITTLQSCY RLKGPEHIIN
260 270 280 290 300
TADLFEMSGV IPEYYLEDYL EVCRSGNYER LEQFVREIGF SAYSVGQMME
310 320 330 340 350
QFVEFIVHHP GLNDPQKATI CDKLGECCFR LQDGGSEYLQ IMDLGCCIIL

ALK
Length:353
Mass (Da):39,555
Last modified:October 1, 2002 - v2
Checksum:i97F2516D7BCA33D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF48768.2.
AY069598 mRNA. Translation: AAL39743.1.
RefSeqiNP_573245.1. NM_133017.4.
UniGeneiDm.2050.

Genome annotation databases

EnsemblMetazoaiFBtr0074472; FBpp0074246; FBgn0030871.
GeneIDi32763.
KEGGidme:Dmel_CG8142.
UCSCiCG8142-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF48768.2.
AY069598 mRNA. Translation: AAL39743.1.
RefSeqiNP_573245.1. NM_133017.4.
UniGeneiDm.2050.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-847740.
STRINGi7227.FBpp0074246.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0074472; FBpp0074246; FBgn0030871.
GeneIDi32763.
KEGGidme:Dmel_CG8142.
UCSCiCG8142-RA. d. melanogaster.

Organism-specific databases

FlyBaseiFBgn0030871. CG8142.

Phylogenomic databases

eggNOGiKOG0989. Eukaryota.
COG0470. LUCA.
GeneTreeiENSGT00550000074917.
KOiK10755.
OMAiRQIFGDM.
OrthoDBiEOG091G0CKT.

Enzyme and pathway databases

ReactomeiR-DME-110312. Translesion synthesis by REV1.
R-DME-110314. Recognition of DNA damage by PCNA-containing replication complex.
R-DME-110320. Translesion Synthesis by POLH.
R-DME-174411. Polymerase switching on the C-strand of the telomere.
R-DME-176187. Activation of ATR in response to replication stress.
R-DME-5651801. PCNA-Dependent Long Patch Base Excision Repair.
R-DME-5655862. Translesion synthesis by POLK.
R-DME-5656121. Translesion synthesis by POLI.
R-DME-5656169. Termination of translesion DNA synthesis.
R-DME-5696397. Gap-filling DNA repair synthesis and ligation in GG-NER.
R-DME-6782135. Dual incision in TC-NER.
R-DME-6782210. Gap-filling DNA repair synthesis and ligation in TC-NER.
R-DME-69091. Polymerase switching.

Miscellaneous databases

GenomeRNAii32763.

Gene expression databases

BgeeiFBgn0030871.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR008921. DNA_pol3_clamp-load_cplx_C.
IPR027417. P-loop_NTPase.
IPR013748. Rep_factorC_C.
PfamiView protein in Pfam
PF00004. AAA. 1 hit.
PF08542. Rep_fac_C. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SUPFAMiSSF48019. SSF48019. 1 hit.
SSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9VX15_DROME
AccessioniPrimary (citable) accession number: Q9VX15
Secondary accession number(s): Q8T033
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: October 1, 2002
Last modified: March 15, 2017
This is version 151 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.