Unreviewed, UniProtKB/TrEMBL Q9VWS4 (Q9VWS4_DROME)

Names and origin

Protein names

Submitted name:
    Wengen EMBL AAF48864.2
Submitted name:
    RE29502p EMBL AAM48414.1
    TNFR superfamily protein Wengen EMBL BAC01264.1

Gene names

Name:	wgn EMBL AAF48864.2 FlyBase FBgn0030941
ORF Names:	CG6531 EMBL AAM48414.1 FlyBase FBgn0030941, Dmel_CG6531 EMBL AAF48864.2

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	apoptosis Non-traceable author statement. Source: FlyBase cell surface receptor linked signal transduction Ref.4 Inferred from genetic interaction. Source: FlyBase
Cellular component	integral to plasma membrane Ref.4 Inferred from direct assay. Source: FlyBase
Molecular function	tumor necrosis factor receptor activity Non-traceable author statement. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VWS4-1 [UniParc]. Last modified October 1, 2002. Version 2. Checksum: BD5E6F5318A82170	FASTA	343	37,829
	10 20 30 40 50 60 MMPPRLPGGH GGAMRSRSSS SGHHLNTTFH KRRRRRQQHH IGGSHISISH GSYLALLLLS 70 80 90 100 110 120 TTCSLVATSA SSSSSAANTD IAPPDPPPVS QVSIASSSPC APQHWWDSQR DRCTPCTRCQ 130 140 150 160 170 180 GEMIPLRPCQ LHTDTICGSI YDLKIDWVVL AKTEPNWKER RKSSEYEHFE HNAPLQHLTH 190 200 210 220 230 240 EQLQQLHEEA AAAWVLDWQT GVLYVAVLTC LVFFSVAACI LIHHMRQWRR MERRLDQDVE 250 260 270 280 290 300 ELSTKLMAKL AEVQSLDGGT FFIGNADALR GLPASAATTH PATTQSGIFQ PQHVLLPEKR 310 320 330 340 GKHQERRILK TLQPGNVYIE ESNAGLGGMG VGLGVRGCSG LKG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAM48414.1.
[4]	"Wengen, a member of the Drosophila tumor necrosis factor receptor superfamily, is required for Eiger signaling." Kanda H., Igaki T., Kanuka H., Yagi T., Miura M. J. Biol. Chem. 277:28372-28375(2002) [PubMed: 12084706] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014298 Genomic DNA. Translation: AAF48864.2. AY118385 mRNA. Translation: AAM48414.1. AB085747 mRNA. Translation: BAC01264.1.
RefSeq	NP_728186.1.
UniGene	Dm.13466
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9VWS4. 2 interactions.
Genome annotation databases
Ensembl	FBgn0030941. Drosophila melanogaster. [Contig view]
GeneID	32849.
KEGG	dme:Dmel_CG6531.
NMPDR	fig|7227.3.peg.18518.
Organism-specific databases
FlyBase	FBgn0030941. wgn.
Phylogenomic databases
HOGENOM	Q9VWS4.
Gene expression databases
ArrayExpress	Q9VWS4.
Family and domain databases
InterPro	IPR001368. TNFR_Cys_rich_reg. [Graphical view]
Pfam	PF00020. TNFR_c6. 1 hit. [Graphical view]
SMART	SM00208. TNFR. 1 hit. [Graphical view]
PROSITE	PS50050. TNFR_NGFR_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	780698.

Entry information

Entry name

Q9VWS4_DROME

Accession

Primary (citable) accession number: Q9VWS4

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	October 1, 2002
Last modified:	June 16, 2009
This is version 57 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)