Unreviewed, UniProtKB/TrEMBL Q9VWL7 (Q9VWL7_DROME)

Names and origin

Protein names

Submitted name:
    RhoGAP18B, isoform C EMBL AAF48921.2

Gene names

Name:	RhoGAP18B EMBL AAF48921.2 FlyBase FBgn0259169
ORF Names:	Dmel_CG42274 EMBL AAF48921.2

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1317 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 Rho-GAP domain. Spearmint SPM000198

Sequences

	Sequence		Length	Mass (Da)
	Q9VWL7-1 [UniParc]. Last modified March 3, 2009. Version 2. Checksum: CDAC7CE1D42EA784	FASTA	1,317	147,350
	10 20 30 40 50 60 MPQQAKDIND NVGMEAHIYE NLPGLTSTPK GHLNAELRKY FPREAIYENL CRGCGYGVFA 70 80 90 100 110 120 AQGRYCHFCQ CIVSGGVVST PPPPPPPPLS TISGESSNIY ENICDLCRGI YSDNERCRCQ 130 140 150 160 170 180 RSETPAKAPA PSTPTTPPTP PTKVKSRSLL GYSKSSAATL TRLFGSLKQL NRSSSLQRRI 190 200 210 220 230 240 FPRTPTTGSS SAGSLEIIHN VDEVFRTQET FDLQRICELK LEQQQLKGSQ SDQHIYGRVR 250 260 270 280 290 300 EPEESQSHKR ERKRPRVSRI RLLQDESTSG SSSLYLNESI CQWMTSLRRQ VHHYDEGPWQ 310 320 330 340 350 360 QPKSVPARDP SSSAEESTVT LRRSTEESAK CADEQAKLVK DFKRKLQQKR AHNVEPEREQ 370 380 390 400 410 420 RRCAITANFV NDYLSALGEE KEAVQHQQVA AIEEHVAVVA IAIQPQVSVS LLRLMQSLAL 430 440 450 460 470 480 SASLHVSVRG FLTAYDKSFS LWLWHQQQQQ RQQPPINGYR RRRARDSVVG VVGDWRRRLP 490 500 510 520 530 540 LFAFSFAGGN DRSVASASVS VSPAISESVD VCAAAASRRR ANRSTRRRGT AIVREEGVCG 550 560 570 580 590 600 GESSTSSNNS KKNNNNNSNN NSGALMAAPK PNGEAERPST NSNNNTINCS SNNNNDNISN 610 620 630 640 650 660 NNNNHHTVDN ESGINNNKNN DGNANCNVNE QQQQQQQQPI TQNCVIKVRR PAPKVPVRNP 670 680 690 700 710 720 NTSLSNPRQI EEEQTKPNGG KKDNLRGNSF AAENSSPEEQ EEESIYQPIW QFKTIEPVDQ 730 740 750 760 770 780 EIIEALPVEG EDEEDEDEED DDVDDEEEDL GDYDESLPSD ADPDVMALQA AAVFAAGVRH 790 800 810 820 830 840 KLSTSTLTKR SKMMMPTPLP SPTASMDHGA WETDMEFMYS RESKEEADET LSLGSTVTNS 850 860 870 880 890 900 TATLGSISST GSSVTGQPKD TPKDLPADQQ PSVVVHPILR NICIFYSQKD PKKYSAIFYD 910 920 930 940 950 960 YHLSLVHQRF MTRIRRPAPP PPAQLATSNT TSLAPRSDDS GCSCEAEDSY NHQHNPTPAI 970 980 990 1000 1010 1020 PKPLKEEWER AVLAAGAVAG KRGVAPRTGR KLRVRSNARL LLTDSVLAWR ETLQDVNCCE 1030 1040 1050 1060 1070 1080 DEEDMIVPVT DILRAQQIQE DNEVQQTQQS TILQRYKSVS IGNLLDLPGE DDKKSIKNRM 1090 1100 1110 1120 1130 1140 RMKFAVNSNV FRINRSPKSE KKSRSRRGQV NSLYLDEQKY PLFAAPLSAL ELNMTDHPNV 1150 1160 1170 1180 1190 1200 PRFVVDVCAY IEQPECIEQD GLYRASGNKV LVDELRKKLT HVYDPRWLKT DDIHTLTSLH 1210 1220 1230 1240 1250 1260 KQFFRELTSP LITQEAYERL GRSLNDDAAI ERMSLAFDDM PEPNRSTLRF LIRHLTRVAA 1270 1280 1290 1300 1310 ASASNRMPST NLAIVWGPCL LSANQIQLDI GRMNMLAKVL IENYDRIFHP DNERLVC

References

[1]

"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.

[2]

"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014298 Genomic DNA. Translation: AAF48921.2.
RefSeq	NP_573352.2.
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	FBgn0030987. Drosophila melanogaster. [Contig view]
GeneID	32898.
Organism-specific databases
FlyBase	FBgn0259169. RhoGAP18B.
Gene expression databases
ArrayExpress	Q9VWL7.
Family and domain databases
InterPro	IPR000198. RhoGAP. [Graphical view]
Gene3D	G3DSA:1.10.555.10. RhoGAP. 1 hit.
Pfam	PF00620. RhoGAP. 1 hit. [Graphical view]
SMART	SM00324. RhoGAP. 1 hit. [Graphical view]
PROSITE	PS50238. RHOGAP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9VWL7_DROME

Accession

Primary (citable) accession number: Q9VWL7

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	March 3, 2009
Last modified:	July 7, 2009
This is version 47 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)