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Protein

40S ribosomal protein S10b

Gene

RpS10b

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • structural constituent of ribosome Source: FlyBase

GO - Biological processi

  • cytoplasmic translation Source: FlyBase
  • ribosomal small subunit assembly Source: GO_Central

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-DME-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DME-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DME-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-DME-72649. Translation initiation complex formation.
R-DME-72689. Formation of a pool of free 40S subunits.
R-DME-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-DME-72702. Ribosomal scanning and start codon recognition.
R-DME-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DME-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DME-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S10b
Gene namesi
Name:RpS10b
Synonyms:RpS10
ORF Names:CG14206
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0261593. RpS10b.

Subcellular locationi

GO - Cellular componenti

  • cytosolic ribosome Source: FlyBase
  • cytosolic small ribosomal subunit Source: FlyBase
  • microtubule associated complex Source: FlyBase
  • nucleus Source: FlyBase
  • ribosome Source: FlyBase

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001163671 – 16040S ribosomal protein S10bAdd BLAST160

Proteomic databases

PaxDbiQ9VWG3.
PRIDEiQ9VWG3.

Expressioni

Gene expression databases

BgeeiFBgn0261593.
GenevisibleiQ9VWG3. DM.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
stumpsO967573EBI-75824,EBI-74922

Protein-protein interaction databases

BioGridi59253. 21 interactors.
IntActiQ9VWG3. 11 interactors.
MINTiMINT-331234.
STRINGi7227.FBpp0074500.

Structurei

3D structure databases

ProteinModelPortaliQ9VWG3.
SMRiQ9VWG3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3344. Eukaryota.
COG5045. LUCA.
GeneTreeiENSGT00440000034918.
InParanoidiQ9VWG3.
KOiK02947.
OMAiQMLMPKK.
OrthoDBiEOG091G0QTW.
PhylomeDBiQ9VWG3.

Family and domain databases

InterProiView protein in InterPro
IPR005326. S10_plectin_N.
PfamiView protein in Pfam
PF03501. S10_plectin. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9VWG3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFMPKAHRVA IYEYLFKEGV IVAKKDFHAQ KHPELESIPN LHVIKAMQSL
60 70 80 90 100
HSRGLVKEQF AWRHYYWYLT NEGIEELRSY LHLPPEIVPS TLKRPARSET
110 120 130 140 150
VRPRPAVGGP RGPGDASKTG EDRSAYRRAP GGSGVDKKGD VGPGAGEVEF
160
RGGFGRGSRN
Length:160
Mass (Da):17,878
Last modified:October 1, 2002 - v2
Checksum:i5955BD98D664FD07
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF48978.2.
AE014298 Genomic DNA. Translation: AAN09507.1.
AY070896 mRNA. Translation: AAL48518.1.
RefSeqiNP_001245758.1. NM_001258829.2.
NP_001285445.1. NM_001298516.1.
NP_608324.1. NM_134480.4.
NP_728273.1. NM_167668.2.
UniGeneiDm.6225.

Genome annotation databases

EnsemblMetazoaiFBtr0074731; FBpp0074500; FBgn0261593.
FBtr0074732; FBpp0074501; FBgn0261593.
FBtr0308192; FBpp0300512; FBgn0261593.
FBtr0344339; FBpp0310720; FBgn0261593.
GeneIDi32953.
KEGGidme:Dmel_CG14206.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF48978.2.
AE014298 Genomic DNA. Translation: AAN09507.1.
AY070896 mRNA. Translation: AAL48518.1.
RefSeqiNP_001245758.1. NM_001258829.2.
NP_001285445.1. NM_001298516.1.
NP_608324.1. NM_134480.4.
NP_728273.1. NM_167668.2.
UniGeneiDm.6225.

3D structure databases

ProteinModelPortaliQ9VWG3.
SMRiQ9VWG3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi59253. 21 interactors.
IntActiQ9VWG3. 11 interactors.
MINTiMINT-331234.
STRINGi7227.FBpp0074500.

Proteomic databases

PaxDbiQ9VWG3.
PRIDEiQ9VWG3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0074731; FBpp0074500; FBgn0261593.
FBtr0074732; FBpp0074501; FBgn0261593.
FBtr0308192; FBpp0300512; FBgn0261593.
FBtr0344339; FBpp0310720; FBgn0261593.
GeneIDi32953.
KEGGidme:Dmel_CG14206.

Organism-specific databases

CTDi32953.
FlyBaseiFBgn0261593. RpS10b.

Phylogenomic databases

eggNOGiKOG3344. Eukaryota.
COG5045. LUCA.
GeneTreeiENSGT00440000034918.
InParanoidiQ9VWG3.
KOiK02947.
OMAiQMLMPKK.
OrthoDBiEOG091G0QTW.
PhylomeDBiQ9VWG3.

Enzyme and pathway databases

ReactomeiR-DME-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DME-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DME-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-DME-72649. Translation initiation complex formation.
R-DME-72689. Formation of a pool of free 40S subunits.
R-DME-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-DME-72702. Ribosomal scanning and start codon recognition.
R-DME-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DME-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DME-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

ChiTaRSiRpS10b. fly.
GenomeRNAii32953.
PROiPR:Q9VWG3.

Gene expression databases

BgeeiFBgn0261593.
GenevisibleiQ9VWG3. DM.

Family and domain databases

InterProiView protein in InterPro
IPR005326. S10_plectin_N.
PfamiView protein in Pfam
PF03501. S10_plectin. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRS10B_DROME
AccessioniPrimary (citable) accession number: Q9VWG3
Secondary accession number(s): A4V4S6, Q8SZG7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2004
Last sequence update: October 1, 2002
Last modified: June 7, 2017
This is version 113 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.