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Protein
Submitted name:

Brivido-1

Gene

brv1

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • calcium channel activity Source: FlyBase
  • calcium ion binding Source: InterPro

GO - Biological processi

  • calcium ion transport Source: FlyBase
  • cellular response to cold Source: FlyBase
  • detection of mechanical stimulus Source: GO_Central
  • detection of temperature stimulus involved in thermoception Source: FlyBase
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Brivido-1Imported
Submitted name:
MIP06652pImported
Gene namesi
Name:brv1Imported
Synonyms:CG9472-RAImported
ORF Names:CG9472Imported, Dmel_CG9472Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0036874. brv1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 27HelicalSequence analysisAdd BLAST22
Transmembranei39 – 58HelicalSequence analysisAdd BLAST20
Transmembranei125 – 143HelicalSequence analysisAdd BLAST19
Transmembranei372 – 393HelicalSequence analysisAdd BLAST22
Transmembranei405 – 426HelicalSequence analysisAdd BLAST22
Transmembranei455 – 475HelicalSequence analysisAdd BLAST21
Transmembranei495 – 518HelicalSequence analysisAdd BLAST24
Transmembranei559 – 581HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiFBgn0036874.

Interactioni

Protein-protein interaction databases

MINTiMINT-1608866.
STRINGi7227.FBpp0074750.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini166 – 591PKD_channelInterPro annotationAdd BLAST426

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3599. Eukaryota.
ENOG410XTGE. LUCA.
GeneTreeiENSGT00700000104221.
OMAiHRNERVN.
OrthoDBiEOG091G03U5.

Family and domain databases

InterProiIPR013122. PKD1_2_channel.
IPR003915. PKD_2.
[Graphical view]
PfamiPF08016. PKD_channel. 1 hit.
[Graphical view]
PRINTSiPR01433. POLYCYSTIN2.

Sequencei

Sequence statusi: Complete.

Q9VVZ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKKFSNIIF YLTLIIIAIC VACIWMFSGF RHEYGKFNMI LVAFLAVTLL
60 70 80 90 100
QILIFTPIKF TIMSLDAAFW PAHQAPETPD ENANVDTFMD NLRLRLRTLR
110 120 130 140 150
SELMITERHR NERVNLKYRL ITEELWLTGK LFLVYFFMAL AFFDELLYFN
160 170 180 190 200
TEATELLFQC NHGDAFGLLS VGDVPDIYFF VVSSLVLAFT DGKNTSGGAP
210 220 230 240 250
WIHAEGTRLL GVVRLRQLRT ESNRLGLSLP VFTERDFSES WTLPYERVPY
260 270 280 290 300
TDKYWPIYTP WLPSVSVARD NLLMGINHVG HMFNYPESKG YKVLLSDTRH
310 320 330 340 350
KSLKIIDYLM KKNWLDANTT ALFMDFSLYN ADANTFTVCT LWVEKFPYQY
360 370 380 390 400
PDGHTRIESH TFVEQLREFT KFGMLMVFVF VVTWLQFTKA FFLKVWYDPR
410 420 430 440 450
QLKTLWVQVD AMIVALSLVV GMIMSVRDNL VQKMIKSVEI AVVVDFLDFR
460 470 480 490 500
EPAQLAYLED VVTGLAVALV TMRLWKVLQF SATFQLFTKT IAMAWDALLC
510 520 530 540 550
TFVITVIFII AIGIATVTIN GNYTSNFRDF PKGIVTVTCF AFGYTNLVYP
560 570 580 590 600
PDIFYGGEWL GILLYTIMGF VVKYMLINLI VSMMRDQMAS VKADRDKKVR
610 620 630 640 650
QRITFWQFLR VEYAHFINYI VKVFHCQKGY QRKNRTVAQN IQRKLNSNEL
660 670 680 690 700
KRRKTKISSI YSETIYVMPI DKDLEQMKYR ERIERTFTLA AILHTQMELM
710 720
ERLMFGDEEG NLPSLDQEDE QVPETEED
Length:728
Mass (Da):84,869
Last modified:May 1, 2000 - v1
Checksum:i42DDCFB4D26723D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA. Translation: AAF49157.1.
BT088910 mRNA. Translation: ACT09407.1.
RefSeqiNP_649116.1. NM_140859.2.
UniGeneiDm.33995.

Genome annotation databases

EnsemblMetazoaiFBtr0074982; FBpp0074750; FBgn0036874.
GeneIDi40116.
KEGGidme:Dmel_CG9472.
UCSCiCG9472-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA. Translation: AAF49157.1.
BT088910 mRNA. Translation: ACT09407.1.
RefSeqiNP_649116.1. NM_140859.2.
UniGeneiDm.33995.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1608866.
STRINGi7227.FBpp0074750.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0074982; FBpp0074750; FBgn0036874.
GeneIDi40116.
KEGGidme:Dmel_CG9472.
UCSCiCG9472-RA. d. melanogaster.

Organism-specific databases

CTDi40116.
FlyBaseiFBgn0036874. brv1.

Phylogenomic databases

eggNOGiKOG3599. Eukaryota.
ENOG410XTGE. LUCA.
GeneTreeiENSGT00700000104221.
OMAiHRNERVN.
OrthoDBiEOG091G03U5.

Miscellaneous databases

GenomeRNAii40116.

Gene expression databases

BgeeiFBgn0036874.

Family and domain databases

InterProiIPR013122. PKD1_2_channel.
IPR003915. PKD_2.
[Graphical view]
PfamiPF08016. PKD_channel. 1 hit.
[Graphical view]
PRINTSiPR01433. POLYCYSTIN2.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9VVZ8_DROME
AccessioniPrimary (citable) accession number: Q9VVZ8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 128 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.