Q9VVX0 (Q9VVX0_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
CG10419 EMBL AAF49187.1

Gene names

Name:	Gem2 FlyBase FBgn0036850
ORF Names:	CG10419 EMBL AAF49187.1 FlyBase FBgn0036850, Dmel_CG10419 EMBL AAF49187.1

Organism

Drosophila melanogaster (Fruit fly) [Reference proteome] EMBL AAF49187.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Sophophora › melanogaster group › melanogaster subgroup

Protein attributes

Sequence length	245 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 1VU2 PDB 1VU3 PDB 4F77 Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	spliceosomal complex assembly Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasmic U snRNP body Inferred from direct assay PubMed 20452345. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VVX0 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 1E9A700ADD97EDFF	FASTA	245	28,751
	10 20 30 40 50 60 MQHEPEDQTF QLQALEICEP DSSFDPQKPP ESGEEYLMHM FYERKRCPAV VTKRSSKIRN 70 80 90 100 110 120 NTGNTTLEML DNPELPPFKC LLPTPEWRDE QVKSFQAARS QVLVLRKELA NNNYDQSGEP 130 140 150 160 170 180 PLTSDQEKWK EFCRNQQPLL STLLHLTQND LELLLEMLSK WLQDPNTTVD LLHDVWLARW 190 200 210 220 230 240 LYATLVCLHL PLEPHVFSTL RYIARTCIHL RNQLKEDEVQ RAAPYNLLLT LTVQVFAQND FKDYI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083-RESEARCH0083(2002) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: Berkeley.
[3]	"Structural basis of assembly chaperone- mediated snRNP formation." Grimm C., Chari A., Pelz J.P., Kuper J., Kisker C., Diederichs K., Stark H., Schindelin H., Fischer U. Mol. Cell 49:692-703(2013) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.10 ANGSTROMS).
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE014296 Genomic DNA. Translation: AAF49187.1.

RefSeq

NP_001262034.1. NM_001275105.1.
NP_649092.1. NM_140835.4.

UniGene

Dm.1995.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1VU2	X-ray	3.10	2/F/N/V/d/l/t	1-245	[»]
1VU3	X-ray	3.10	F/N/V/d/l/t	1-245	[»]
4F77	X-ray	3.10	2/F/N/V/d/l/t	1-245	[»]

ProteinModelPortal

Q9VVX0.

SMR

Q9VVX0. Positions 29-241.

ModBase

Search...

Protein-protein interaction databases

IntAct

Q9VVX0. 2 interactions.

MINT

MINT-1625145.

Proteomic databases

PRIDE

Q9VVX0.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblMetazoa

FBtr0075032; FBpp0074799; FBgn0036850.
FBtr0330093; FBpp0303126; FBgn0036850.

GeneID

40087.

KEGG

dme:Dmel_CG10419.

UCSC

CG10419-RA. d. melanogaster.

Organism-specific databases

CTD

40087.

FlyBase

FBgn0036850. Gem2.

Phylogenomic databases

GeneTree

ENSGT00390000013814.

InParanoid

Q9VVX0.

KO

K13130.

OMA

YSPTLKW.

PhylomeDB

Q9VVX0.

Gene expression databases

ArrayExpress

Q9VVX0.

Bgee

Q9VVX0.

Family and domain databases

InterPro

IPR007022. SIP1.
IPR017364. Survival_motor_neuron_Gemin2.
[Graphical view]

PANTHER

PTHR12794. PTHR12794. 1 hit.

PIRSF

PIRSF038038. SMN_Gemin2. 1 hit.

ProtoNet

Search...

Other

GenomeRNAi

40087.

NextBio

816928.

Entry information

Entry name

Q9VVX0_DROME

Accession

Primary (citable) accession number: Q9VVX0

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	May 29, 2013
This is version 81 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)