Unreviewed, UniProtKB/TrEMBL Q9VV74 (Q9VV74_DROME)

Names and origin

Protein names

Submitted name:
    Survival motor neuron EMBL AAF49446.1
Submitted name:
    LD23602p EMBL AAL13758.1
    Survival motor neuron protein SMN EMBL AAG17893.1

Gene names

Name:	Smn EMBL AAF49446.1 FlyBase FBgn0036641
ORF Names:	CG16725 FlyBase FBgn0036641, Dmel_CG16725 EMBL AAF49446.1

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	226 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	spliceosome assembly Inferred from electronic annotation. Source: InterPro
Cellular component	Cajal body Inferred from direct assay. Source: FlyBase cytoplasm Inferred from direct assay. Source: FlyBase
Molecular function	RNA binding Inferred from electronic annotation. Source: InterPro identical protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VV74-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 9F00D85A3E9614C7	FASTA	226	24,622
	10 20 30 40 50 60 MSDETNAAVW DDSLLVKTYD ESVGLAREAL ARRLADSTNK REEENAAAAE EEAGEISATG 70 80 90 100 110 120 GATSPEPVSF KVGDYARATY VDGVDYEGAV VSINEEKGTC VLRYLGYENE QEVLLVDLLP 130 140 150 160 170 180 SWGKRVRREQ FLIAKKDEDE QLSRPKASAG SHSKTPKSSR RSRISGGLVM PPMPPVPPMI 190 200 210 220 VGQGDGAEQD FVAMLTAWYM SGYYTGLYQG KKEASTTSGK KKTPKK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	"Phosphoproteome analysis of Drosophila melanogaster embryos." Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P. J. Proteome Res. 7:1675-1682(2008) [PubMed: 18327897] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.
[4]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Li P., Liao G., Miranda A., Mungall C.J., Nunoo J. , Pacleb J., Paragas V., Park S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAL13758.1.
[5]	"Disruption of SMN function by ectopic expression of the human SMN gene in Drosophila." Miguel-Aliaga I., Chan Y.B., Davies K.E., van den Heuvel M. FEBS Lett. 486:99-102(2000) [PubMed: 11113446] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014296 Genomic DNA. Translation: AAF49446.1. AF296281 mRNA. Translation: AAG17893.1. AY058529 mRNA. Translation: AAL13758.1.
RefSeq	NP_524112.1.
UniGene	Dm.2679
3D structure databases
HSSP	HSSP built from PDB template 1MHN based on UniProtKB Q16637.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9VV74. 13 interactions.
STRING	Q9VV74.
Proteomic databases
PRIDE	Q9VV74.
Genome annotation databases
Ensembl	FBtr0075395; FBpp0075153; FBgn0036641; Drosophila melanogaster. [Genome view]
GeneID	39844.
KEGG	dme:Dmel_CG16725.
NMPDR	fig|7227.3.peg.10169.
UCSC	CG16725-RA. d. melanogaster.
Organism-specific databases
CTD	39844.
FlyBase	FBgn0036641. Smn.
Phylogenomic databases
HOGENOM	Q9VV74.
OMA	GYENEQE
OrthoDB	EOG9X3H6M
PhylomeDB	Q9VV74.
Gene expression databases
ArrayExpress	Q9VV74.
Family and domain databases
InterPro	IPR010304. Survival_motor_neuron. IPR002999. Tudor. [Graphical view]
Pfam	PF06003. SMN. 1 hit. [Graphical view]
SMART	SM00333. TUDOR. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	815685.

Entry information

Entry name

Q9VV74_DROME

Accession

Primary (citable) accession number: Q9VV74

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	November 24, 2009
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)