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Protein
Submitted name:

LD22449p

Gene

Tsf2

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • iron ion binding Source: FlyBase

GO - Biological processi

  • septate junction assembly Source: FlyBase
Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-DME-114608. Platelet degranulation.
R-DME-1222556. ROS, RNS production in response to bacteria.
R-DME-6798695. Neutrophil degranulation.
R-DME-6799990. Metal sequestration by antimicrobial proteins.
R-DME-917937. Iron uptake and transport.

Protein family/group databases

MEROPSiS60.976.

Names & Taxonomyi

Protein namesi
Submitted name:
LD22449pImported
Submitted name:
Transferrin 2Imported
Gene namesi
Name:Tsf2Imported
ORF Names:CG10620Imported, Dmel_CG10620Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0036299. Tsf2.

Subcellular locationi

GO - Cellular componenti

  • anchored component of plasma membrane Source: FlyBase
  • cytosol Source: FlyBase
  • early endosome Source: FlyBase
  • extracellular region Source: InterPro
  • plasma membrane Source: FlyBase
  • recycling endosome Source: FlyBase
  • septate junction Source: FlyBase
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500878612822 – 819Sequence analysisAdd BLAST798

Expressioni

Gene expression databases

BgeeiFBgn0036299.

Interactioni

Protein-protein interaction databases

MINTiMINT-1565184.
STRINGi7227.FBpp0075698.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 373Transferrin-likeInterPro annotationAdd BLAST341
Domaini450 – 796Transferrin-likeInterPro annotationAdd BLAST347

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IEAI. Eukaryota.
ENOG410XQ36. LUCA.
GeneTreeiENSGT00390000001619.
OMAiFDNTNGH.
OrthoDBiEOG091G0242.

Family and domain databases

InterProiIPR001156. Transferrin-like_dom.
IPR018195. Transferrin_Fe_BS.
[Graphical view]
PfamiPF00405. Transferrin. 2 hits.
[Graphical view]
PRINTSiPR00422. TRANSFERRIN.
SMARTiSM00094. TR_FER. 2 hits.
[Graphical view]
PROSITEiPS00205. TRANSFERRIN_LIKE_1. 1 hit.
PS00206. TRANSFERRIN_LIKE_2. 1 hit.
PS51408. TRANSFERRIN_LIKE_4. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9VTZ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSLVFVAL VGALCFTLAN AQHHYDEHKT TRMVWCTKSQ AEQYKCQNLT
60 70 80 90 100
VAIERDRALF DEVFLNLTCF MAYSADECIH HIDREKAHIT TLDAGDVFTA
110 120 130 140 150
GRYNSLIPIM QEKLEGGFAD YQSVAVIKKG SLPDLNNLRD MRNKRVCFPW
160 170 180 190 200
VGSLAGWIVP IHTLQREGGM EVVDCNNQVK TAASYFNNSC AVYSLSDKHN
210 220 230 240 250
PIGDNSDKLC TLCTGKIPGG RCSSADPYFG YEGAFKCLLE KGDVAFLRHS
260 270 280 290 300
TVNEMLQTTE FKNIAPDTFE LLCRDGRRAS INDYRQCNWG QVPADAIVTS
310 320 330 340 350
SARSFSDRKQ YQQFLKRIAE LYSDGTRDDQ SRQGGQSFNS RNNINDQNAY
360 370 380 390 400
GQFDNNDPYR TQNQYDQYRS ERLDSSFAEE RNQQDGTNTS ILYEKFRIFE
410 420 430 440 450
SKRYGKPNLL FQDSSRALTV IPEDDQSFTK YLGPAINFIY GIRECPVPAM
460 470 480 490 500
TLCVTSENEL DKCIKMRTAL KAHLLKPELI CKKMHSHINC MQFIEAGKAD
510 520 530 540 550
ISVFDAGDVY TGGLNYDLVP FMSEVYNLGE PEYYVVAVAK EDDPDTELTY
560 570 580 590 600
LKGKNTCHTG INTAAGWTYP MALFISNGWI RPYGCDSVRA AAEYFTKSCV
610 620 630 640 650
PGAISNEYNT GVPYDSMCDL CHGTSYRYCR RDASEEYYGH TGAFRCLVEG
660 670 680 690 700
GGHVAFMKHT TVMESTGGKR KEWWARNALN DDFELLCTDG TRAEIQDYKR
710 720 730 740 750
CNLGKVKANA VVTRGGVNYN ETQMNAYINL LTYAQQLYGR KEVDAFSFSM
760 770 780 790 800
FSSPIGHYDL IFQDATRQLQ VIPPNKRRYD AYLGSDFMRA RRITDCYAGA
810
SQLALSVGLL LVGSLVAML
Length:819
Mass (Da):92,325
Last modified:May 1, 2000 - v1
Checksum:iBD2053EAD4A7BF9E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA. Translation: AAF49900.1.
BT004490 mRNA. Translation: AAO42654.1.
RefSeqiNP_524044.1. NM_079320.3.
UniGeneiDm.944.

Genome annotation databases

EnsemblMetazoaiFBtr0075966; FBpp0075698; FBgn0036299.
GeneIDi39435.
KEGGidme:Dmel_CG10620.
UCSCiCG10620-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA. Translation: AAF49900.1.
BT004490 mRNA. Translation: AAO42654.1.
RefSeqiNP_524044.1. NM_079320.3.
UniGeneiDm.944.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1565184.
STRINGi7227.FBpp0075698.

Protein family/group databases

MEROPSiS60.976.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0075966; FBpp0075698; FBgn0036299.
GeneIDi39435.
KEGGidme:Dmel_CG10620.
UCSCiCG10620-RA. d. melanogaster.

Organism-specific databases

CTDi39435.
FlyBaseiFBgn0036299. Tsf2.

Phylogenomic databases

eggNOGiENOG410IEAI. Eukaryota.
ENOG410XQ36. LUCA.
GeneTreeiENSGT00390000001619.
OMAiFDNTNGH.
OrthoDBiEOG091G0242.

Enzyme and pathway databases

ReactomeiR-DME-114608. Platelet degranulation.
R-DME-1222556. ROS, RNS production in response to bacteria.
R-DME-6798695. Neutrophil degranulation.
R-DME-6799990. Metal sequestration by antimicrobial proteins.
R-DME-917937. Iron uptake and transport.

Miscellaneous databases

GenomeRNAii39435.

Gene expression databases

BgeeiFBgn0036299.

Family and domain databases

InterProiIPR001156. Transferrin-like_dom.
IPR018195. Transferrin_Fe_BS.
[Graphical view]
PfamiPF00405. Transferrin. 2 hits.
[Graphical view]
PRINTSiPR00422. TRANSFERRIN.
SMARTiSM00094. TR_FER. 2 hits.
[Graphical view]
PROSITEiPS00205. TRANSFERRIN_LIKE_1. 1 hit.
PS00206. TRANSFERRIN_LIKE_2. 1 hit.
PS51408. TRANSFERRIN_LIKE_4. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9VTZ5_DROME
AccessioniPrimary (citable) accession number: Q9VTZ5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 126 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.