Unreviewed, UniProtKB/TrEMBL Q9VTX7 (Q9VTX7_DROME)

Names and origin

Protein names

Submitted name:
    Eyegone, isoform A EMBL AAF49918.2
Submitted name:
    Eyegone, isoform B EMBL AAX52747.1

Gene names

Name:	eyg EMBL AAF49918.2 FlyBase FBgn0000625
ORF Names:	Dmel_CG10488 EMBL AAF49918.2

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	670 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location	Nucleus By similarity Spearmint SPM001523 RuleBase RU000491V1.
Sequence similarities	Contains 1 paired domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation Spearmint SPM001523 RuleBase RU000491V1
Cellular component	Nucleus Spearmint SPM001523 RuleBase RU000491V1
Domain	Homeobox RuleBase RU000682V4 Paired box Spearmint SPM001523 RuleBase RU000491V1
Ligand	DNA-binding Spearmint SPM001523 RuleBase RU000491V1
Molecular function	Developmental protein Spearmint SPM001523 RuleBase RU000491V1
Gene Ontology (GO)
Biological process	compound eye morphogenesis Inferred from mutant phenotype. Source: FlyBase regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro salivary gland morphogenesis Traceable author statement. Source: FlyBase transcription Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	protein binding Inferred from physical interaction. Source: IntAct sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro transcription factor activity Non-traceable author statement. Source: FlyBase transcription repressor activity Inferred from mutant phenotype. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VTX7-1 [UniParc]. Last modified October 1, 2002. Version 2. Checksum: 3A036269ADDD1B8A	FASTA	670	70,111
	10 20 30 40 50 60 MLIEPTLNRD LGSLTVANSG LSAAHWKMEP HPQRITSLAP HASSVAAASV AAAAAAAAAA 70 80 90 100 110 120 AAAAAGAGSG AVAGGGGATS TSPTSVQIPP GFGGGGSTGG IPHGAGGPTG STLNTLMSQH 130 140 150 160 170 180 RLLEFSRFGG LRGYDIAQHM LTQQGAVSKL LGSLRPPGLI GGSKPKVATP TVVSKIEQYK 190 200 210 220 230 240 RENPTIFAWE IRERLISEGV CTNATAPSVS SINRILRNRA AERVATEFAR TAAYGLYPPP 250 260 270 280 290 300 PHPYGSFTWH PAGNVPGGQG VPPPPPPSAL WSVAAPTLAN LPPSAASAVP VSTCGSLSSA 310 320 330 340 350 360 HLMAGGAGGT PTNRAISPGS GSHDTLESAD ENRHIDSDYL DDDDEPKFRR NRTTFSPEQL 370 380 390 400 410 420 EELEKEFDKS HYPCVSTRER LSSRTSLSEA RVQVWFSNRR AKWRRHQRMN LLKRQRSSPA 430 440 450 460 470 480 NPLHSQQSND APASSPTPSN HSSASTSAPV APVPPPQQPL PLCGDHSPQG PPPSVLLHPL 490 500 510 520 530 540 HGPPGGHHHH HPLHLPTHPA ALQLLSHYHQ QQQQQQQQQH QQQQQQHHQQ QQQLSPSGCN 550 560 570 580 590 600 PAANHLSMGG ERSAFRSLVS SPSAAAFLGL ARQYAVAASL TVAEEQRSRL HYSAGGLGSG 610 620 630 640 650 660 GEGTGPNTNT TQSGGSTMTV DNSSSDSDEE INVHDDSDGE IESSAATAAK VARLSSSDAP 670 ATLQFLKHDR

References

[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014296 Genomic DNA. Translation: AAF49918.2. AE014296 Genomic DNA. Translation: AAX52747.1.
RefSeq	NP_001014582.1. NP_524042.2.
UniGene	Dm.2059
3D structure databases
HSSP	HSSP built from PDB template 1K78 based on UniProtKB Q02548.
SMR	Q9VTX7. Positions 118-216, 161-217, 171-402, 349-404.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9VTX7. 25 interactions.
STRING	Q9VTX7.
Genome annotation databases
Ensembl	FBtr0075979; FBpp0075711; FBgn0000625; Drosophila melanogaster. [Genome view] FBtr0100170; FBpp0099525; FBgn0000625; Drosophila melanogaster. [Genome view]
GeneID	39419.
KEGG	dme:Dmel_CG10488.
NMPDR	fig|7227.3.peg.9541.
UCSC	CG10488-RA. d. melanogaster.
Organism-specific databases
CTD	39419.
FlyBase	FBgn0000625. eyg.
Phylogenomic databases
InParanoid	Q9VTX7.
OMA	ATEFART.
PhylomeDB	Q9VTX7.
Gene expression databases
ArrayExpress	Q9VTX7.
Family and domain databases
InterPro	IPR001356. Homeobox. IPR017970. Homeobox_CS. IPR009057. Homeodomain-like. IPR012287. Homeodomain-rel. IPR001523. Paired_box_N. IPR011991. WHTH_trsnscrt_rep_DNA-bd. [Graphical view]
Gene3D	G3DSA:1.10.10.60. Homeodomain-rel. 1 hit. G3DSA:1.10.10.10. Wing_hlx_DNA_bd. 1 hit.
Pfam	PF00046. Homeobox. 1 hit. PF00292. PAX. 1 hit. [Graphical view]
SMART	SM00389. HOX. 1 hit. SM00351. PAX. 1 hit. [Graphical view]
PROSITE	PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. PS51057. PAIRED_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	813541.

Entry information

Entry name

Q9VTX7_DROME

Accession

Primary (citable) accession number: Q9VTX7

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	October 1, 2002
Last modified:	February 9, 2010
This is version 75 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)