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Protein

60S ribosomal protein L10a-2

Gene

RpL10Ab

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • RNA binding Source: GO_Central
  • structural constituent of ribosome Source: FlyBase

GO - Biological processi

  • centrosome duplication Source: FlyBase
  • cytoplasmic translation Source: FlyBase
  • maturation of LSU-rRNA Source: GO_Central
  • translation Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-DME-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DME-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DME-72689. Formation of a pool of free 40S subunits.
R-DME-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DME-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DME-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L10a-2
Gene namesi
Name:RpL10Ab
ORF Names:CG7283
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0036213. RpL10Ab.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001258291 – 21760S ribosomal protein L10a-2Add BLAST217

Proteomic databases

PaxDbiQ9VTP4.
PRIDEiQ9VTP4.

Expressioni

Gene expression databases

BgeeiFBgn0036213.
GenevisibleiQ9VTP4. DM.

Interactioni

Protein-protein interaction databases

BioGridi64699. 9 interactors.
IntActiQ9VTP4. 3 interactors.
MINTiMINT-1551463.
STRINGi7227.FBpp0075764.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4V6Welectron microscopy6.00Cz1-217[»]
ProteinModelPortaliQ9VTP4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L1P family.Curated

Phylogenomic databases

eggNOGiKOG1570. Eukaryota.
COG0081. LUCA.
GeneTreeiENSGT00390000008767.
InParanoidiQ9VTP4.
KOiK02865.
OMAiDFFIAQA.
OrthoDBiEOG091G0KUI.
PhylomeDBiQ9VTP4.

Family and domain databases

CDDicd00403. Ribosomal_L1. 1 hit.
Gene3Di3.30.190.20. 2 hits.
3.40.50.790. 1 hit.
InterProiIPR002143. Ribosomal_L1.
IPR023674. Ribosomal_L1-like.
IPR028364. Ribosomal_L1/biogenesis.
IPR016094. Ribosomal_L1_2-a/b-sand.
IPR016095. Ribosomal_L1_3-a/b-sand.
[Graphical view]
PfamiPF00687. Ribosomal_L1. 1 hit.
[Graphical view]
PIRSFiPIRSF002155. Ribosomal_L1. 1 hit.
SUPFAMiSSF56808. SSF56808. 1 hit.
PROSITEiPS01199. RIBOSOMAL_L1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9VTP4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASKVSRDTL YEGVNGLLEA SAKKKRGFLE TVELQIGLKN YDPQKDKRFS
60 70 80 90 100
GTVKLKHIPR PKMKVCILGD QQHCDEAKAN NVDFMDAEAL KKLNKNKKLV
110 120 130 140 150
KKLAKSYDAF LASESLIKQI PRLLGPGLNK AGKFPALLSH QESMIGKIEE
160 170 180 190 200
VKSTIKFQMK KVLCLSVAVG HVGMKSDELA QNVNLSINFL VSLLKKNWQN
210
VRSLHVKSSM GPPQRLY
Length:217
Mass (Da):24,274
Last modified:October 1, 2002 - v2
Checksum:i92AD096A38A0E3C2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA. Translation: AAF50002.2.
BT014654 mRNA. Translation: AAT27278.1.
RefSeqiNP_648514.1. NM_140257.2.
UniGeneiDm.23143.

Genome annotation databases

EnsemblMetazoaiFBtr0076032; FBpp0075764; FBgn0036213.
GeneIDi39338.
KEGGidme:Dmel_CG7283.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA. Translation: AAF50002.2.
BT014654 mRNA. Translation: AAT27278.1.
RefSeqiNP_648514.1. NM_140257.2.
UniGeneiDm.23143.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4V6Welectron microscopy6.00Cz1-217[»]
ProteinModelPortaliQ9VTP4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi64699. 9 interactors.
IntActiQ9VTP4. 3 interactors.
MINTiMINT-1551463.
STRINGi7227.FBpp0075764.

Proteomic databases

PaxDbiQ9VTP4.
PRIDEiQ9VTP4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0076032; FBpp0075764; FBgn0036213.
GeneIDi39338.
KEGGidme:Dmel_CG7283.

Organism-specific databases

CTDi39338.
FlyBaseiFBgn0036213. RpL10Ab.

Phylogenomic databases

eggNOGiKOG1570. Eukaryota.
COG0081. LUCA.
GeneTreeiENSGT00390000008767.
InParanoidiQ9VTP4.
KOiK02865.
OMAiDFFIAQA.
OrthoDBiEOG091G0KUI.
PhylomeDBiQ9VTP4.

Enzyme and pathway databases

ReactomeiR-DME-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DME-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DME-72689. Formation of a pool of free 40S subunits.
R-DME-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DME-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DME-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

ChiTaRSiRpL10Ab. fly.
GenomeRNAii39338.
PROiQ9VTP4.

Gene expression databases

BgeeiFBgn0036213.
GenevisibleiQ9VTP4. DM.

Family and domain databases

CDDicd00403. Ribosomal_L1. 1 hit.
Gene3Di3.30.190.20. 2 hits.
3.40.50.790. 1 hit.
InterProiIPR002143. Ribosomal_L1.
IPR023674. Ribosomal_L1-like.
IPR028364. Ribosomal_L1/biogenesis.
IPR016094. Ribosomal_L1_2-a/b-sand.
IPR016095. Ribosomal_L1_3-a/b-sand.
[Graphical view]
PfamiPF00687. Ribosomal_L1. 1 hit.
[Graphical view]
PIRSFiPIRSF002155. Ribosomal_L1. 1 hit.
SUPFAMiSSF56808. SSF56808. 1 hit.
PROSITEiPS01199. RIBOSOMAL_L1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiR10AB_DROME
AccessioniPrimary (citable) accession number: Q9VTP4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: October 1, 2002
Last modified: November 30, 2016
This is version 119 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.