Unreviewed, UniProtKB/TrEMBL Q9VSW5 (Q9VSW5_DROME)

Names and origin

Protein names

Submitted name:
    Kinesin-like protein at 67A EMBL AAF50296.1
Submitted name:
    RE52076p EMBL AAL49055.1

Gene names

Name:	Klp67A EMBL AAF50296.1 FlyBase FBgn0004379
ORF Names:	CG10923 FlyBase FBgn0004379, Dmel_CG10923 EMBL AAF50296.1

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	814 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the kinesin-like protein family. RuleBase RU000394V1 Contains 1 kinesin-motor domain. RuleBase RU000394V1 Spearmint SPM001752

Ontologies

Keywords
Cellular component	Microtubule RuleBase RU000394V1
Ligand	ATP-binding RuleBase RU000394V1 Spearmint SPM001752 Nucleotide-binding
Molecular function	Motor protein RuleBase RU000394V1 Spearmint SPM001752
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	centrosome separation Inferred from mutant phenotype. Source: FlyBase cytokinesis Inferred from mutant phenotype. Source: FlyBase male meiotic chromosome movement towards spindle pole Inferred from mutant phenotype. Source: FlyBase microtubule polymerization Inferred from mutant phenotype. Source: FlyBase microtubule-based movement Inferred from electronic annotation. Source: InterPro mitotic spindle organization Inferred from mutant phenotype. Source: FlyBase sister chromatid biorientation Inferred from mutant phenotype. Source: FlyBase spindle assembly Inferred from mutant phenotype. Source: FlyBase
Cellular component	cytoplasm Inferred from direct assay. Source: FlyBase kinesin complex Traceable author statement. Source: FlyBase nucleus Inferred from direct assay. Source: FlyBase
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro microtubule motor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VSW5-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 6AD4CF16279C19A5	FASTA	814	92,350
	10 20 30 40 50 60 MPSEQHTNIK VAVRVRPYNV RELEQKQRSI IKVMDRSALL FDPDEEDDEF FFQGAKQPYR 70 80 90 100 110 120 DITKRMNKKL TMEFDRVFDI DNSNQDLFEE CTAPLVDAVL NGYNCSVFVY GATGAGKTFT 130 140 150 160 170 180 MLGSEAHPGL TYLTMQDLFD KIQAQSDVRK FDVGVSYLEV YNEHVMNLLT KSGPLKLRED 190 200 210 220 230 240 NNGVVVSGLC LTPIYSAEEL LRMLMLGNSH RTQHPTDANA ESSRSHAIFQ VHIRITERKT 250 260 270 280 290 300 DTKRTVKLSM IDLAGSERAA STKGIGVRFK EGASINKSLL ALGNCINKLA DGLKHIPYRD 310 320 330 340 350 360 SNLTRILKDS LGGNCRTLMV ANVSMSSLTY EDTYNTLKYA SRAKKIRTTL KQNVLKSKMP 370 380 390 400 410 420 TEFYVKKIDE VVAENERLKE RNKALEAKAT QLERAGNSGF DPLELKTWYS KIDAVYAAAR 430 440 450 460 470 480 QLQEHVLGMR SKIKNINYRQ TLKKELEEFR KLMCVDQRVC QEDFRRFANY MSTLTSQMEK 490 500 510 520 530 540 YKEELPSWLS KMEIAYQDLE SLKREVNKSK AYQILIVYVK YKDLELQLTK QNIFNNHVNA 550 560 570 580 590 600 INQELVENLD LMRKSFRTAC EVLNQTYDRL EDGQKLTPEI EAVFERLLRK MRFADSEANT 610 620 630 640 650 660 KMAEMNPLAV PVALRSSAQE EEEPTCSLTA SAKKRQRQAA QSDDDLHLSM EDFDSQDTES 670 680 690 700 710 720 DSEELHRTFK RPRNLNETQV LGPCSSSSSS STSSSSSARK ALTATVTKPR TVQQRLVSDL 730 740 750 760 770 780 ISDQNVRGGN EKIKKALLKS NHFTAQGLQR TLAAASLAKE NVKYNANYVR KSPRALMAKA 790 800 810 LAGTSTLARK PLGSASKEPP LVKFNRAASF RLKK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAL49055.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014296 Genomic DNA. Translation: AAF50296.1. AY071433 mRNA. Translation: AAL49055.1.
RefSeq	NP_523992.2.
UniGene	Dm.2789
3D structure databases
HSSP	HSSP built from PDB template 1I5S based on UniProtKB P33173.
ModBase	Search...
Proteomic databases
PRIDE	Q9VSW5.
Genome annotation databases
Ensembl	FBgn0004379. Drosophila melanogaster. [Contig view]
GeneID	39068.
KEGG	dme:Dmel_CG10923.
NMPDR	fig|7227.3.peg.9029.
Organism-specific databases
FlyBase	FBgn0004379. Klp67A.
Phylogenomic databases
OMA	Q9VSW5. QVHIRIT.
Gene expression databases
ArrayExpress	Q9VSW5.
Family and domain databases
InterPro	IPR001752. Kinesin_motor. [Graphical view]
Gene3D	G3DSA:3.40.850.10. kinesin_motor. 1 hit.
Pfam	PF00225. Kinesin. 1 hit. [Graphical view]
PRINTS	PR00380. KINESINHEAVY.
SMART	SM00129. KISc. 1 hit. [Graphical view]
PROSITE	PS50067. KINESIN_MOTOR_DOMAIN2. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	811761.

Entry information

Entry name

Q9VSW5_DROME

Accession

Primary (citable) accession number: Q9VSW5

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	June 16, 2009
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)