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Protein
Submitted name:

Pixie, isoform A

Gene

pix

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • ATPase activity Source: UniProtKB-EC
  • ATP binding Source: FlyBase
  • iron ion binding Source: GO_Central
  • ribosomal small subunit binding Source: FlyBase
  • translation initiation factor binding Source: UniProtKB

GO - Biological processi

  • cell growth Source: FlyBase
  • growth Source: FlyBase
  • negative regulation of neuron apoptotic process Source: FlyBase
  • nuclear-transcribed mRNA catabolic process, non-stop decay Source: FlyBase
  • ribosomal subunit export from nucleus Source: GO_Central
  • translation Source: FlyBase
  • translational initiation Source: FlyBase
  • translational termination Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseImported

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DME-382556. ABC-family proteins mediated transport.

Names & Taxonomyi

Protein namesi
Submitted name:
Pixie, isoform AImported (EC:3.6.1.3Imported)
Submitted name:
Pixie, isoform BImported
Submitted name:
RE71924pImported
Gene namesi
Name:pixImported
ORF Names:CG5651Imported, Dmel_CG5651Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0086706. pix.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: FlyBase
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiFBgn0086706.

Interactioni

GO - Molecular functioni

  • translation initiation factor binding Source: UniProtKB

Protein-protein interaction databases

MINTiMINT-930375.
STRINGi7227.FBpp0076284.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini15 – 45314Fe-4S ferredoxin-typeInterPro annotationAdd
BLAST
Domaini54 – 83304Fe-4S ferredoxin-typeInterPro annotationAdd
BLAST
Domaini78 – 323246ABC transporterInterPro annotationAdd
BLAST
Domaini350 – 570221ABC transporterInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 2 ABC transporter domains.UniRule annotation

Phylogenomic databases

eggNOGiKOG0063. Eukaryota.
COG1245. LUCA.
GeneTreeiENSGT00390000015089.
KOiK06174.
OMAiAYKPQYI.
OrthoDBiEOG091G038V.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR013283. ABCE.
IPR027417. P-loop_NTPase.
IPR007209. RNaseL-inhib_metal-bd_dom.
[Graphical view]
PANTHERiPTHR19248. PTHR19248. 1 hit.
PfamiPF00005. ABC_tran. 2 hits.
PF00037. Fer4. 1 hit.
PF04068. RLI. 1 hit.
[Graphical view]
PRINTSiPR01868. ABCEFAMILY.
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 2 hits.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9VSS1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRRKENEEV DKQTRIAIVS DDKCKPKRCR QECKKTCPVV RMGKLCIEVT
60 70 80 90 100
PTSKIASLSE ELCIGCGICV KKCPFEAITI INLPSNLEKH TTHRYSKNSF
110 120 130 140 150
KLHRLPIPRP GEVLGLVGQN GIGKSTALKI LAGKQKPNLG KYANPPDWTE
160 170 180 190 200
ILSYFRGSEL QNYFTKILED NLKALVKPQY VDQIPKAVRG AVGDLLDKKD
210 220 230 240 250
ERELQTKICE MLDLSHIRDR EIAQLSGGEL QRFAIAMVCI QNADIFMFDE
260 270 280 290 300
PSSYLDVKQR LNAALTIRSL LHPTKFIIVV EHDLSVLDYL SDFICCLYGV
310 320 330 340 350
PGCYGVVTMP FSVREGINIF LDGFVPTENM RFRTESLTFK VSESATEEEI
360 370 380 390 400
KRMNHYVYPA MVKTLGKFEL TVEKGHFSDS EILVLLGENG TGKTTFIRML
410 420 430 440 450
AGNLQPDGEV ELPMLNISYK PQKISPKFQN HVRHLLHDKI RDAYVHPQFI
460 470 480 490 500
ADVMKPMKIE EIMDQEVQNL SGGELQRVAL VLCLGKPADV YLIDEPSAYL
510 520 530 540 550
DSEQRLVAAK VIKRYILHAK KTGFVVEHDF IMATYLADRV IVIEGQPSVK
560 570 580 590 600
TTAFSPQSLL NGMNRFLELL GITFRRDPNN FRPRINKNNS VKDTEQKRSG
610
QFFFLEDEAC N
Length:611
Mass (Da):69,298
Last modified:May 1, 2000 - v1
Checksum:iF4747F4D69F9E1C2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA. Translation: AAF50342.1.
AY089644 mRNA. Translation: AAL90382.1.
AE014296 Genomic DNA. Translation: AAN11979.1.
RefSeqiNP_648272.1. NM_140015.3.
NP_729435.1. NM_168306.2.
UniGeneiDm.7778.

Genome annotation databases

EnsemblMetazoaiFBtr0076557; FBpp0076284; FBgn0086706.
FBtr0076558; FBpp0076285; FBgn0086706.
GeneIDi39027.
KEGGidme:Dmel_CG5651.
UCSCiCG5651-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA. Translation: AAF50342.1.
AY089644 mRNA. Translation: AAL90382.1.
AE014296 Genomic DNA. Translation: AAN11979.1.
RefSeqiNP_648272.1. NM_140015.3.
NP_729435.1. NM_168306.2.
UniGeneiDm.7778.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-930375.
STRINGi7227.FBpp0076284.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0076557; FBpp0076284; FBgn0086706.
FBtr0076558; FBpp0076285; FBgn0086706.
GeneIDi39027.
KEGGidme:Dmel_CG5651.
UCSCiCG5651-RA. d. melanogaster.

Organism-specific databases

CTDi39027.
FlyBaseiFBgn0086706. pix.

Phylogenomic databases

eggNOGiKOG0063. Eukaryota.
COG1245. LUCA.
GeneTreeiENSGT00390000015089.
KOiK06174.
OMAiAYKPQYI.
OrthoDBiEOG091G038V.

Enzyme and pathway databases

ReactomeiR-DME-382556. ABC-family proteins mediated transport.

Miscellaneous databases

ChiTaRSipix. fly.
GenomeRNAii39027.

Gene expression databases

BgeeiFBgn0086706.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR013283. ABCE.
IPR027417. P-loop_NTPase.
IPR007209. RNaseL-inhib_metal-bd_dom.
[Graphical view]
PANTHERiPTHR19248. PTHR19248. 1 hit.
PfamiPF00005. ABC_tran. 2 hits.
PF00037. Fer4. 1 hit.
PF04068. RLI. 1 hit.
[Graphical view]
PRINTSiPR01868. ABCEFAMILY.
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 2 hits.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9VSS1_DROME
AccessioniPrimary (citable) accession number: Q9VSS1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: September 7, 2016
This is version 150 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.