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Protein
Submitted name:

Glutathione S transferase O1

Gene

GstO1

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • glutathione dehydrogenase (ascorbate) activity Source: FlyBase
  • glutathione transferase activity Source: FlyBase
  • transferase activity, transferring sulfur-containing groups Source: FlyBase

GO - Biological processi

  • glutathione metabolic process Source: FlyBase
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported, TransferaseImported

Enzyme and pathway databases

ReactomeiR-DME-156581. Methylation.
R-DME-156590. Glutathione conjugation.
R-DME-196836. Vitamin C (ascorbate) metabolism.

Names & Taxonomyi

Protein namesi
Submitted name:
Glutathione S transferase O1Imported (EC:1.5.4.1Imported, EC:1.8.5.1Imported, EC:2.5.1.18Imported, EC:2.8.-.-Imported)
Submitted name:
Glutathione S-transferase omega classImported
Submitted name:
RE55814pImported
Gene namesi
Name:GstO1Imported
ORF Names:CG6662Imported, Dmel_CG6662Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0035907. GstO1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiFBgn0035907.

Interactioni

Protein-protein interaction databases

MINTiMINT-1732147.
STRINGi7227.FBpp0076376.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 102GST N-terminalInterPro annotationAdd BLAST83
Domaini107 – 243GST C-terminalInterPro annotationAdd BLAST137

Phylogenomic databases

eggNOGiKOG0406. Eukaryota.
ENOG410XSIX. LUCA.
GeneTreeiENSGT00390000005479.
KOiK00799.
OMAiFGQFINA.
OrthoDBiEOG091G0IEA.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR005442. GST_omega.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF13417. GST_N_3. 1 hit.
[Graphical view]
PRINTSiPR01625. GSTRNSFRASEO.
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9VSL6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNTQHLTIG SPKPVFPDDG ILKLYSMRFC PYAHRVHLVL DAKKIPYHAI
60 70 80 90 100
YINLRDKPEW FSLVSSSTKV PALELVKEQG NPVLIESLII CDYLDEKYPE
110 120 130 140 150
VPLYPKDLLK KAQEKILIER FGQFINAFYY LLLHDNPEQL VDTDHYAGLV
160 170 180 190 200
VYEEELKRRC TKFFGGDSPG MLDYMMWPWC ERFDSLKYTF EQKFELSPER
210 220 230 240 250
FPTLIKWRDL MIQDRAVKCF YLDGQTHAKY MNSRRSGQAD YNMLYNEAKR

VKLG
Length:254
Mass (Da):29,974
Last modified:May 1, 2000 - v1
Checksum:iAD35DC0F5F79E4AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA. Translation: AAF50402.1.
AY071499 mRNA. Translation: AAL49121.1.
GQ351317 Genomic DNA. Translation: ACZ02428.1.
RefSeqiNP_648237.1. NM_139980.3.
UniGeneiDm.5896.

Genome annotation databases

EnsemblMetazoaiFBtr0076652; FBpp0076376; FBgn0035907.
GeneIDi38975.
KEGGidme:Dmel_CG6662.
UCSCiCG6662-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA. Translation: AAF50402.1.
AY071499 mRNA. Translation: AAL49121.1.
GQ351317 Genomic DNA. Translation: ACZ02428.1.
RefSeqiNP_648237.1. NM_139980.3.
UniGeneiDm.5896.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1732147.
STRINGi7227.FBpp0076376.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0076652; FBpp0076376; FBgn0035907.
GeneIDi38975.
KEGGidme:Dmel_CG6662.
UCSCiCG6662-RA. d. melanogaster.

Organism-specific databases

CTDi9446.
FlyBaseiFBgn0035907. GstO1.

Phylogenomic databases

eggNOGiKOG0406. Eukaryota.
ENOG410XSIX. LUCA.
GeneTreeiENSGT00390000005479.
KOiK00799.
OMAiFGQFINA.
OrthoDBiEOG091G0IEA.

Enzyme and pathway databases

ReactomeiR-DME-156581. Methylation.
R-DME-156590. Glutathione conjugation.
R-DME-196836. Vitamin C (ascorbate) metabolism.

Miscellaneous databases

GenomeRNAii38975.

Gene expression databases

BgeeiFBgn0035907.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR005442. GST_omega.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF13417. GST_N_3. 1 hit.
[Graphical view]
PRINTSiPR01625. GSTRNSFRASEO.
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9VSL6_DROME
AccessioniPrimary (citable) accession number: Q9VSL6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: September 7, 2016
This is version 155 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.