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Protein
Submitted name:

Glutathione S transferase O2, isoform A

Gene

GstO2

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • glutathione binding Source: FlyBase
  • glutathione dehydrogenase (ascorbate) activity Source: FlyBase
  • glutathione transferase activity Source: FlyBase
  • protein homodimerization activity Source: FlyBase
  • transferase activity, transferring sulfur-containing groups Source: FlyBase

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseImported, TransferaseImported

Enzyme and pathway databases

ReactomeiR-DME-156581 Methylation
R-DME-156590 Glutathione conjugation
R-DME-196836 Vitamin C (ascorbate) metabolism

Names & Taxonomyi

Protein namesi
Submitted name:
Glutathione S transferase O2, isoform AImported (EC:1.5.4.1Imported, EC:1.8.5.1Imported, EC:2.5.1.18Imported, EC:2.8.-.-Imported)
Submitted name:
Glutathione S-transferase omega classImported
Gene namesi
Name:GstO2Imported
Synonyms:anon-EST:Posey29Imported, CG6673-AImported, CG6673-BImported, CG6673AImported, CG6673BImported, Dmel\CG6673Imported, DmGSTO1Imported, DmGSTO2aImported, DmGSTO2bImported, GSTO2Imported, gsto2Imported, GSTO2aImported, GSTO2bImported
ORF Names:CG6673Imported, CG6673-RAImported, Dmel_CG6673Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0035906 GstO2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiQ9VSL5

Expressioni

Gene expression databases

BgeeiFBgn0035906
ExpressionAtlasiQ9VSL5 baseline and differential

Interactioni

GO - Molecular functioni

  • protein homodimerization activity Source: FlyBase

Protein-protein interaction databases

STRINGi7227.FBpp0076378

Structurei

3D structure databases

SMRiQ9VSL5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 103GST N-terminalInterPro annotationAdd BLAST83
Domaini108 – 251GST C-terminalInterPro annotationAdd BLAST144

Phylogenomic databases

eggNOGiKOG0406 Eukaryota
ENOG410XSIX LUCA
GeneTreeiENSGT00390000005479
OrthoDBiEOG091G0IEA

Family and domain databases

InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR005442 GST_omega
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF13417 GST_N_3, 1 hit
PRINTSiPR01625 GSTRNSFRASEO
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Q9VSL5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALPQKHFKR GSTKPELPED GVPRFFSMAF CPFSHRVRLM LAAKHIEHHK
60 70 80 90 100
IYVDLIEKPE WYKDFSPLGK VPALQLTGVK DQPTLVESLI IAEYLDQQYP
110 120 130 140 150
QTRLFPTDPL QKALDKILIE RFAPVVSAIY PVLTCNPNAP KDAIPNFENA
160 170 180 190 200
LDVFEVELGK RGTPYFAGQH IGIVDYMIWP WFERFPSMKI NTEQKYELDT
210 220 230 240 250
KRFEKLLKWR DLMTQDEVVQ KTALDVQLHA EFQKSKTLGN PQYDIAFKGT

P
Length:251
Mass (Da):29,077
Last modified:March 1, 2001 - v2
Checksum:i6E9D9F456E9D1190
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF50404.2
GQ351317 Genomic DNA Translation: ACZ02426.1
RefSeqiNP_729388.1, NM_168277.2
UniGeneiDm.3631

Genome annotation databases

EnsemblMetazoaiFBtr0076654; FBpp0076378; FBgn0035906
GeneIDi38974
UCSCiCG6673-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ9VSL5_DROME
AccessioniPrimary (citable) accession number: Q9VSL5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: March 1, 2001
Last modified: May 23, 2018
This is version 155 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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