Unreviewed, UniProtKB/TrEMBL Q9VSE9 (Q9VSE9_DROME)

Names and origin

Protein names

Submitted name:
    Estrogen-related receptor, isoform A EMBL AAF50473.1
Submitted name:
    Estrogen-related receptor EMBL AAL37553.1
    GH28308p EMBL AAK93056.1

Gene names

Name:	ERR EMBL AAF50473.1 FlyBase FBgn0035849
ORF Names:	CG7404 FlyBase FBgn0035849, Dmel_CG7404 EMBL AAF50473.1

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	484 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the nuclear hormone receptor family. RuleBase RU000377V1 Contains 1 nuclear receptor DNA-binding domain. Spearmint SPM001723

Ontologies

Keywords
Biological process	Transcription Transcription regulation RuleBase RU004334V0 Spearmint SPM001723
Cellular component	Nucleus RuleBase RU004334V0 Spearmint SPM001723
Domain	Zinc-finger RuleBase RU004334V0
Ligand	DNA-binding RuleBase RU004334V0 Spearmint SPM001723 Metal-binding Zinc
Molecular function	Receptor RuleBase RU004334V0
Gene Ontology (GO)
Biological process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro
Cellular component	nucleus Inferred from electronic annotation. Source: InterPro
Molecular function	protein binding Inferred from physical interaction. Source: IntAct sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro steroid hormone receptor activity Inferred from electronic annotation. Source: InterPro transcription factor activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VSE9-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 252E3AD07C84A311	FASTA	484	53,245
	10 20 30 40 50 60 MSDGVSILHI KQEVDTPSAS CFSPSSKSTA TQSGTNGLKS SPSVSPERQL CSSTTSLSCD 70 80 90 100 110 120 LHNVSLSNDG DSLKGSGTSG GNGGGGGGGT SGGNATNASA GAGSGSVRDE LRRLCLVCGD 130 140 150 160 170 180 VASGFHYGVA SCEACKAFFK RTIQGNIEYT CPANNECEIN KRRRKACQAC RFQKCLLMGM 190 200 210 220 230 240 LKEGVRLDRV RGGRQKYRRN PVSNSYQTMQ LLYQSNTTSL CDVKILEVLN SYEPDALSVQ 250 260 270 280 290 300 TPPPQVHTTS ITNDEASSSS GSIKLESSVV TPNGTCIFQN NNNNDPNEIL SVLSDIYDKE 310 320 330 340 350 360 LVSVIGWAKQ IPGFIDLPLN DQMKLLQVSW AEILTLQLTF RSLPFNGKLC FATDVWMDEH 370 380 390 400 410 420 LAKECGYTEF YYHCVQIAQR MERISPRREE YYLLKALLLA NCDILLDDQS SLRAFRDTIL 430 440 450 460 470 480 NSLNDVVYLL RHSSAVSHQQ QLLLLLPSLR QADDILRRFW RGIARDEVIT MKKLFLEMLE PLAR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	Stapleton M., Carlson J., Chavez C., Frise E., George R., Pacleb J., Park S., Wan K., Yu C., Celniker S. Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAK93056.1.
[4]	"Identification and characterization of the Drosophila ortholog of vertebrate estrogen-related receptor gene and its product." Lehman J., Wherry S., Talmadge C., Davis J.R., Kiss I., Eudy J.D., Chase B.A., Sumegi J. Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014296 Genomic DNA. Translation: AAF50473.1. AY051632 mRNA. Translation: AAK93056.1. AF359420 mRNA. Translation: AAL37553.1.
RefSeq	NP_729340.1.
UniGene	Dm.882
3D structure databases
HSSP	HSSP built from PDB template 1LO1 based on UniProtKB O95718.
SMR	Q9VSE9. Positions 112-198.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9VSE9. 15 interactions.
Proteomic databases
PRIDE	Q9VSE9.
Genome annotation databases
Ensembl	FBgn0035849. Drosophila melanogaster. [Contig view]
GeneID	38912.
Organism-specific databases
FlyBase	FBgn0035849. ERR.
Gene expression databases
ArrayExpress	Q9VSE9.
Family and domain databases
InterPro	IPR008946. Nucl_hormone_rcpt_ligand-bd. IPR000536. Nucl_hrmn_rcpt_lig-bd_core. IPR001723. Str_hrmn_rcpt. IPR000324. VitD_rcpt. IPR001628. Znf_hrmn_rcpt. IPR013088. Znf_NHR/GATA. [Graphical view]
Gene3D	G3DSA:1.10.565.10. Nucl_hrmn_rcpt_lig_bd. 1 hit. G3DSA:3.30.50.10. Znf_NHR/GATA. 1 hit.
Pfam	PF00104. Hormone_recep. 1 hit. PF00105. zf-C4. 1 hit. [Graphical view]
PRINTS	PR00398. STRDHORMONER. PR00047. STROIDFINGER. PR00350. VITAMINDR.
ProDom	PD000035. Znf_C4steroid. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00430. HOLI. 1 hit. SM00399. ZnF_C4. 1 hit. [Graphical view]
PROSITE	PS00031. NUCLEAR_REC_DBD_1. 1 hit. PS51030. NUCLEAR_REC_DBD_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	810976.

Entry information

Entry name

Q9VSE9_DROME

Accession

Primary (citable) accession number: Q9VSE9

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	June 16, 2009
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)