Unreviewed, UniProtKB/TrEMBL Q9VSD9 (Q9VSD9_DROME)

Names and origin

Protein names

Submitted name:
    Smt3 activating enzyme 2 EMBL AAF31704.1

Gene names

Name:	Uba2 FlyBase FBgn0029113
Synonyms:	SAE2 EMBL AAF31704.1
ORF Names:	CG7528 FlyBase FBgn0029113

Organism

Drosophila melanogaster (Fruit fly) EMBL AAF31704.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	700 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

Ontologies

Gene Ontology (GO)
Biological process	positive regulation of NF-kappaB transcription factor activity Ref.1 Inferred from direct assay. Source: FlyBase protein modification process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from direct assay. Source: FlyBase nucleus Inferred from direct assay. Source: FlyBase
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction. Source: IntAct small protein activating enzyme activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
	Q9VSI1	1	EBI-108249,EBI-116855

Sequences

	Sequence		Length	Mass (Da)
	Q9VSD9-1 [UniParc]. Last modified July 5, 2004. Version 3. Checksum: D16F5E3E6151D22B	FASTA	700	77,681
	10 20 30 40 50 60 MAAAINGVFP PTLHELVKKS KVLVVGAGGI GCEVLKNLVL SGFTDIEIID LDTIDLSNLN 70 80 90 100 110 120 RQFLFHREHV GKSKARVARE SALSFNPDAK ITAYHDSVTS TDYGVNFFKK FDLVLNALDN 130 140 150 160 170 180 RADRNHVNRM CLNADVPLIE SGTAGYNGQV ELIKRGLTQC YECTPKDKQR SFPGCTIRNT 190 200 210 220 230 240 PSEPIHCIVW AKHLFNQLFG ESLEDEDISP DAADPDAKEK DGGDGNGEPK GDGKEKGEES 250 260 270 280 290 300 KEEKEAKEDT ANGNIMRINT RQWAKDCNYD AGKLFNKFFN EDITYLLRMS NLWKTRKAPV 310 320 330 340 350 360 PVQWDTLLPE GSSGDQKDVA KQHHKVWSIE ECAQVFANSL KELSANFLKL EGDDTLAWDK 370 380 390 400 410 420 DDQPAMDFVA ACANVRSHIF YIEPKSRFEN KSMAGNIIPA IATTNAITAG ISVMRAFKVL 430 440 450 460 470 480 EAKWEQCQAV YARLRPNARN HFLVPDASLP GPNPNCHVCA SDPAITLKID TKRMRIKELR 490 500 510 520 530 540 DEVLVKTLNM LNPDVTVQSN GSILISSEEG ETECNDGKLL SELNIVDGVI LKCDDFFQNY 550 560 570 580 590 600 ELSIIISHFD AERDENLFEV VADASQLKPK DEDQKEAVKD KEDEPKSAKK RSTNGEGDSK 610 620 630 640 650 660 DDGPSTSKRS RPNEVVEEDD DDCLVIEEDE DQADVVVVAT DKLSVQSPPK SGSKRKPCEV 670 680 690 700 IEDEDITEIL ESSDDEPAGP TKCKRSRLDD SNPVAVISID

References

[1]	"A functional interaction between dorsal and components of the Smt3 conjugation machinery." Bhaskar V., Valentine S.A., Courey A.J. J. Biol. Chem. 275:4033-4040(2000) [PubMed: 10660560] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF218864 mRNA. Translation: AAF31704.1.
3D structure databases
HSSP	HSSP built from PDB template 1JWA based on UniProtKB P12282.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9VSD9. 5 interactions.
Genome annotation databases
Ensembl	FBgn0029113. Drosophila melanogaster. [Contig view]
Organism-specific databases
FlyBase	FBgn0029113. Uba2.
Gene expression databases
ArrayExpress	Q9VSD9.
Family and domain databases
InterPro	IPR000594. ThiF_NAD_FAD_bd. IPR000127. UBact_repeat. IPR019572. Ubiquitin-activating_enzyme. IPR018074. UBQ-activ_enz_E1_AS. [Graphical view]
Pfam	PF00899. ThiF. 1 hit. PF10585. UBA_e1_thiolCys. 1 hit. PF02134. UBACT. 1 hit. [Graphical view]
PROSITE	PS00865. UBIQUITIN_ACTIVAT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9VSD9_DROME

Accession

Primary (citable) accession number: Q9VSD9
Secondary accession number(s): Q9U4A1

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	July 5, 2004
Last modified:	June 16, 2009
This is version 45 of the entry and version 3 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)