Q9VSC2 (Q9VSC2_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Extra-extra EMBL AAF50503.1

Submitted name:
RE39081p EMBL AAL89903.1

Gene names

Name:	exex FlyBase FBgn0041156 EMBL AAF50503.1
ORF Names:	CG8254 FlyBase FBgn0041156 EMBL AAL89903.1, Dmel_CG8254 EMBL AAF50503.1

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	525 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location

Nucleus By similarity RuleBase RU000682.

Ontologies

Keywords
Cellular component	Nucleus RuleBase RU000682
Domain	Homeobox RuleBase RU000682
Ligand	DNA-binding RuleBase RU000682
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	axon target recognition Inferred from mutant phenotype. Source: FlyBase central nervous system development Inferred from mutant phenotype. Source: FlyBase
Cellular component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VSC2 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 2F361B164D982EFE	FASTA	525	56,770
	10 20 30 40 50 60 MSSAQVSQQP PPPPLTASSS TSMPSQLLLS HIQHHSSSLH HQRSHQRSSP PAQDYDQGSN 70 80 90 100 110 120 QSTLSPRSQI TPSPPAASPT HSAATTGSPV STYTPALSPG GAQDSSQTES GQSSQMPLLV 130 140 150 160 170 180 APMPVGTGPP HSHPPPPHPR LYVEGFPPPH HVPHPHPALG TYPLPRLPLM LPANPPGVPS 190 200 210 220 230 240 GAAAPPPVSP QPAANHLSHS GATMATTTLL PPAQSQPKKS FCIDALLAKS QHQSGEPQPI 250 260 270 280 290 300 IVDDRLAALH YARDQAELNH AFVTASNAAA AAQAAASAAG GISEQEALQR IRDSREYDSP 310 320 330 340 350 360 SPDGMSRSES PTSSHRSSPP ISPGCEDQQQ PHGALHPQHL SMRMSDFHDE FKKPIPPHSP 370 380 390 400 410 420 IRPQDFPLYA GGHPYQLLAQ GGSAFHRPLD PSGKPIPIPM GHNFMPSQLQ FEFLARAGML 430 440 450 460 470 480 HHRIPELAAY PHHAILGKTR RPRTAFTSQQ LLELEKQFKQ NKYLSRPKRF EVASGLMLSE 490 500 510 520 TQVKIWFQNR RMKWKRSKKA QQEAKERAKA NQQQQQQQQT PSAAS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[3]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAL89903.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014296 Genomic DNA. Translation: AAF50503.1. AY084165 mRNA. Translation: AAL89903.1.
RefSeq	NP_648164.1. NM_139907.2.
UniGene	Dm.5205.
3D structure databases
HSSP	HSSP built from PDB template 1B72 based on UniProtKB P14653.
ProteinModelPortal	Q9VSC2.
SMR	Q9VSC2. Positions 443-499.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9VSC2.
Proteomic databases
PRIDE	Q9VSC2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0076751; FBpp0076468; FBgn0041156.
GeneID	38884.
KEGG	dme:Dmel_CG8254.
NMPDR	fig|7227.3.peg.8763.
UCSC	CG8254-RA. d. melanogaster.
Organism-specific databases
CTD	38884.
FlyBase	FBgn0041156. exex.
Phylogenomic databases
eggNOG	inNOG11499.
GeneTree	EMGT00070000025675.
InParanoid	Q9VSC2.
OMA	HHRIPEL.
OrthoDB	EOG431ZFJ.
PhylomeDB	Q9VSC2.
Gene expression databases
ArrayExpress	Q9VSC2.
Bgee	Q9VSC2.
Family and domain databases
InterPro	IPR001356. Homeobox. IPR017970. Homeobox_CS. IPR020479. Homeobox_eu. IPR009057. Homeodomain-like. IPR012287. Homeodomain-rel. [Graphical view]
Gene3D	G3DSA:1.10.10.60. Homeodomain-rel. 1 hit.
Pfam	PF00046. Homeobox. 1 hit. [Graphical view]
PRINTS	PR00024. HOMEOBOX.
SMART	SM00389. HOX. 1 hit. [Graphical view]
SUPFAM	SSF46689. Homeodomain_like. 1 hit.
PROSITE	PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	810844.

Entry information

Entry name

Q9VSC2_DROME

Accession

Primary (citable) accession number: Q9VSC2

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	January 25, 2012
This is version 96 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)