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Q9VRL2

- GOSR2_DROME

UniProt

Q9VRL2 - GOSR2_DROME

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Protein

Probable Golgi SNAP receptor complex member 2

Gene
membrin, CG4780
Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network By similarity.

GO - Molecular functioni

  1. SNAP receptor activity Source: FlyBase

GO - Biological processi

  1. phagocytosis Source: FlyBase
  2. protein transport Source: UniProtKB-KW
  3. terminal branching, open tracheal system Source: FlyBase
  4. trachea morphogenesis Source: FlyBase
  5. vesicle-mediated transport Source: FlyBase
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

ReactomeiREACT_180717. XBP1(S) activates chaperone genes.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable Golgi SNAP receptor complex member 2
Gene namesi
Name:membrin
ORF Names:CG4780
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000000803: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0260856. membrin.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 194194Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei195 – 21521Helical; Anchor for type IV membrane protein; Reviewed predictionAdd
BLAST
Topological domaini216 – 2161Vesicular Reviewed prediction

GO - Cellular componenti

  1. Golgi membrane Source: UniProtKB-SubCell
  2. Golgi stack Source: InterPro
  3. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 216216Probable Golgi SNAP receptor complex member 2PRO_0000212553Add
BLAST

Proteomic databases

PaxDbiQ9VRL2.
PRIDEiQ9VRL2.

Expressioni

Gene expression databases

BgeeiQ9VRL2.

Interactioni

Protein-protein interaction databases

BioGridi64080. 26 interactions.
DIPiDIP-21257N.
IntActiQ9VRL2. 1 interaction.
MINTiMINT-820161.

Structurei

3D structure databases

ProteinModelPortaliQ9VRL2.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili62 – 10342 Reviewed predictionAdd
BLAST

Sequence similaritiesi

Belongs to the GOSR2 family.

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG148687.
GeneTreeiENSGT00490000043403.
InParanoidiQ9VRL2.
KOiK08496.
OMAiQNAHRGM.
OrthoDBiEOG73RBCP.
PhylomeDBiQ9VRL2.

Family and domain databases

InterProiIPR027027. GOSR2/Membrin/Bos1.
[Graphical view]
PIRSFiPIRSF028865. Membrin-2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9VRL2-1 [UniParc]FASTAAdd to Basket

« Hide

MESLYHQTNN VVKDIERDFQ RLSQLSAQES LDVENGIQLK ITQANANCDR    50
LDVLLYKVPP SQRQSSKLRV DQLKYDLRHL QTSLQTARER RQRRMQEISE 100
REQLLNHRFT ANSAQPEETR LQLDYELQHH TQLGNAHRGV DDMIASGSGI 150
LESLISQRMT LGGAHKRIQA IGSTLGLSNH TMKLIERRLV EDRRIFIGGV 200
VVTLLIIALI IYFLVL 216
Length:216
Mass (Da):24,833
Last modified:May 1, 2000 - v1
Checksum:i3CD23EA81BA9851F
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti125 – 1251Y → H in AAM51119. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014296 Genomic DNA. Translation: AAF50783.1.
AY119259 mRNA. Translation: AAM51119.1.
BT044445 mRNA. Translation: ACH92510.1.
RefSeqiNP_647960.1. NM_139703.4.
UniGeneiDm.18872.

Genome annotation databases

EnsemblMetazoaiFBtr0077145; FBpp0076849; FBgn0260856.
GeneIDi38614.
KEGGidme:Dmel_CG4780.
UCSCiCG4780-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014296 Genomic DNA. Translation: AAF50783.1 .
AY119259 mRNA. Translation: AAM51119.1 .
BT044445 mRNA. Translation: ACH92510.1 .
RefSeqi NP_647960.1. NM_139703.4.
UniGenei Dm.18872.

3D structure databases

ProteinModelPortali Q9VRL2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 64080. 26 interactions.
DIPi DIP-21257N.
IntActi Q9VRL2. 1 interaction.
MINTi MINT-820161.

Proteomic databases

PaxDbi Q9VRL2.
PRIDEi Q9VRL2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0077145 ; FBpp0076849 ; FBgn0260856 .
GeneIDi 38614.
KEGGi dme:Dmel_CG4780.
UCSCi CG4780-RA. d. melanogaster.

Organism-specific databases

CTDi 38614.
FlyBasei FBgn0260856. membrin.

Phylogenomic databases

eggNOGi NOG148687.
GeneTreei ENSGT00490000043403.
InParanoidi Q9VRL2.
KOi K08496.
OMAi QNAHRGM.
OrthoDBi EOG73RBCP.
PhylomeDBi Q9VRL2.

Enzyme and pathway databases

Reactomei REACT_180717. XBP1(S) activates chaperone genes.

Miscellaneous databases

GenomeRNAii 38614.
NextBioi 809534.
PROi Q9VRL2.

Gene expression databases

Bgeei Q9VRL2.

Family and domain databases

InterProi IPR027027. GOSR2/Membrin/Bos1.
[Graphical view ]
PIRSFi PIRSF028865. Membrin-2. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Drosophila melanogaster."
    Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
    , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
    Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  2. Cited for: GENOME REANNOTATION.
    Strain: Berkeley.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Berkeley.
    Tissue: Embryo.
  4. Carlson J.W., Booth B., Frise E., Park S., Wan K.H., Yu C., Celniker S.E.
    Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Berkeley.
  5. "A genomic analysis of membrane trafficking and neurotransmitter release in Drosophila."
    Littleton J.T.
    J. Cell Biol. 150:F77-F82(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiGOSR2_DROME
AccessioniPrimary (citable) accession number: Q9VRL2
Secondary accession number(s): B5RJH1, Q8MRU9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: September 3, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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