Q9VQL6 (Q9VQL6_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
GH22259p EMBL ACZ67868.1

Submitted name:
V(2)k05816 EMBL AAF51149.1
EC=1.-.-.- EMBL AAF51149.1
EC=2.3.1.38 EMBL AAF51149.1
EC=2.3.1.39 EMBL AAF51149.1
EC=2.3.1.41 EMBL AAF51149.1
EC=3.1.-.- EMBL AAF51149.1

Gene names

Name:	v(2)k05816 FlyBase FBgn0042627
Synonyms:	v(2)k05816-RA EMBL ACZ67868.1
ORF Names:	Dmel_CG3524 EMBL AAF51149.1

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	2409 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Acyltransferase EMBL AAF51149.1 Hydrolase EMBL AAF51149.1 Oxidoreductase EMBL AAF51149.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	lipid particle Inferred from direct assay. Source: FlyBase
Molecular function	3-oxoacyl-[acyl-carrier-protein] synthase activity Inferred from electronic annotation. Source: EC [acyl-carrier-protein] S-acetyltransferase activity Inferred from electronic annotation. Source: EC [acyl-carrier-protein] S-malonyltransferase activity Inferred from electronic annotation. Source: EC acyl carrier activity Inferred from electronic annotation. Source: InterPro cofactor binding Inferred from electronic annotation. Source: InterPro hydrolase activity, acting on ester bonds Inferred from electronic annotation. Source: InterPro nucleotide binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VQL6 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 2EF5E700057AC734	FASTA	2,409	265,872
	10 20 30 40 50 60 MPSRKKAQGE SAAGEDADIV ISGLSGKLPE SSNIEEFKYN LLNGIDMVTD EPRRWEAGIY 70 80 90 100 110 120 GLPERMAKMK DSDLEKFDDK FFSVHQKQAE LMDPCMRMLL ELTHEAIIDA GINPVQLRGS 130 140 150 160 170 180 RTGVYIGLSF VETEHEIPNM EPSSINGYCL TGCARAMFAN RISYTFDFKG PSFIVDTACS 190 200 210 220 230 240 SSLVALNHAF ADMRAGRCDY ALVAGVNLIL KPIFALQFLR LGIVSHDGSC KTFDAAANGY 250 260 270 280 290 300 ARADTCAVVL LQRRKEAKRV YASILNVRTN TDGFKEQGVT FPDGRMQQAL LEETYSEIGL 310 320 330 340 350 360 NPDEVVYVEA HGSGTPVGDD QEANMLSNFF CRPSRSTPLL IGSVKSNMGH AEPASGVSAL 370 380 390 400 410 420 AKMIIAMEEG IIPKNLHYRT PNPSVPALVE GKLKVVDRNL PWQGGIVGLN SFGFGGANAH 430 440 450 460 470 480 VVLKSHTKAK EPKACPKAGE AEQSLSLVTC SGRTEDAVNQ LLKVATEQRH DQELLTLIND 490 500 510 520 530 540 IHSHPIPLHP FRGYAVLGTS GCVKEEVLPY EEEERPIWFV YAGMGSQWAR MAKDLMQLEV 550 560 570 580 590 600 FRNSIQHCAE VLAQVDFDLI DVLTRSTERT FDNMLYSFVS VSAVQVALTD LLRVLDIRPD 610 620 630 640 650 660 GIIGHSAGEL GAAYMDGCLT AEQTVLAAYW RGRSVLDTPD LPRGKMAAVG LSWEQIGSQI 670 680 690 700 710 720 PKDCYPVCHN SDDNCTVSGP PSSMDAMIED LTAKGIFVRE VGSGGYAFHS PYIEGAAPML 730 740 750 760 770 780 RRSLERLITE PKKKSIRWLS TSVKEAEWDS EKNHLASAGY FINNLISPVL FHQAVKRIPQ 790 800 810 820 830 840 NALIVEIAPH GLFRAILRSL SPQISYVSLM QRGHANNFEF LLSQLGRLYA AGGQPQILKI 850 860 870 880 890 900 SPSIPYPVSR GTPMLGSLVG WDHTQKWNYP KFKGGRQAGQ LSVELDLGKE ENVYLAGHTI 910 920 930 940 950 960 DGRVLFPATG YMTLAWMSLA QQQGLDYLRT PVLFEDVVFH RATILSVGTV VKLTLNFFPG 970 980 990 1000 1010 1020 SSSFEICEGT SLVTSGKIRL VSNVQQEQLQ LSSLPGIAGS NKLSTKDIYK ELRLRGYDYT 1030 1040 1050 1060 1070 1080 GVFQGILESD ISAVTGQLQW ADNWISFMDT MLQFRILSND IRELYVPTGI ERALIDPLKH 1090 1100 1110 1120 1130 1140 LELAKKHQQK LTVNWHRNIS VVKCGGVEIH KMKTAQTQRR SGGQSPPSLE RYRFWPHSQH 1150 1160 1170 1180 1190 1200 LGQREEQEKS RSTALAVAIQ LIIENSGGAV KLKGVELAGS RSTLDALSAV QLLELIEREP 1210 1220 1230 1240 1250 1260 ILVGDMAVVT SSSNESELGE QLKEHGIRVI VKDIKAGAVE QQCHFVYSVN MLAQNSVKDL 1270 1280 1290 1300 1310 1320 QHCLDSLKSD SGFLLLEEAA SRYNIIGKEK LNKLKLVSVL EQFFGTDRVL VLVRKLSKVQ 1330 1340 1350 1360 1370 1380 SSQALTLHLT NKQFKWVNEL KNSIAKAQAE EKNLYLVAQG EPNSGALGLM NCLKREAGGH 1390 1400 1410 1420 1430 1440 FLRLYLILDE GVPQFSLDDP FYAAQLAKDL VVNVYRNGSW GSYRHLKMES RPPMLPVEQA 1450 1460 1470 1480 1490 1500 YVNTLVKGDL SSLRWIESPR SSPIQSQLEP CTVYYAPLNF RDVMLASGKL GVDALPGDLA 1510 1520 1530 1540 1550 1560 YQDCVLGLEF AGRDSCGRRV MAMVTAKSLA TNCLANRNLL WEVPSKWTME QASTVPCVYA 1570 1580 1590 1600 1610 1620 TVYYALVVRG QMKEGERILI HAGSGGVGQA AISVALAHGL TVFTTVGSKE KREFLLKRFP 1630 1640 1650 1660 1670 1680 KLKAKNIGNS RDTSFEQLIM SETHGNGVEL VLNSLSEEKL QASIRCLALN GRFLEIGKFD 1690 1700 1710 1720 1730 1740 LSNNTPLGMS VFLKNTSFHG ILLDSVMEGE EEMQLMVAKL VAEGIKSGAV QPLPTTVFAE 1750 1760 1770 1780 1790 1800 QEIEKAFRFM ASGKHIGKVV IKVRLEEEQQ AALPRLRQIQ AIPRSYMHPE KSYILVGGLG 1810 1820 1830 1840 1850 1860 GFGLELANWL VSRGARFLVL SSRSGVKSGY QALMIRRWHD RGVQVQIDTN DVTTAVGCQR 1870 1880 1890 1900 1910 1920 LLEVSNKLAL VGGIFNLAAV LRDGLIEDQS PKNFEKVSAP KLLATIHLDK ISREICPALE 1930 1940 1950 1960 1970 1980 YFVCFSSLSC GRGNMGQTNY GLANSTMERI CEQRQEYGYP GTAIQWGAIG DTGLIIEHMG 1990 2000 2010 2020 2030 2040 NNETVVGGTL PQRMISCLET LDLFLQQPHP VMASMVVAEK RKTEQANRLS LIATIANIMG 2050 2060 2070 2080 2090 2100 LRDVKSVSDK TTLFDLGMDS LMSTEIKQTL ERHFDLVLSA QEIRQLTFSA LRQIDAQEPP 2110 2120 2130 2140 2150 2160 SASVSSPSAS STLSRIKEEA CVEVQPQSDE TRKVFAKEVL PQEVMVRLRS KAPVASEDPA 2170 2180 2190 2200 2210 2220 VFFLAPIEGF TIAVEALAAS LTCPAYGLQC TEQVPLDSIE ACAAYYLRQI QKLQPLGPYH 2230 2240 2250 2260 2270 2280 IVGYSYGCLL AHAIAVALEQ RRFGVKVIML DGAPTMASGY VQEAKKQTDD LNRQQSMTLA 2290 2300 2310 2320 2330 2340 YFGALLADVD YNQLLQLLDG VQTWPSKLDK LADTLAGYTQ QTREVIKKAA CMFKQKLLLS 2350 2360 2370 2380 2390 2400 ESYKGAKQLH SDVVLIKSAE HNAIMAQDYG LKEICSAQID MHVVEGTHRT FLKEPHTLQI IERVLRKRP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[3]	Carlson J., Booth B., Frise E., Park S., Wan K., Yu C., Celniker S. Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL ACZ67868.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014134 Genomic DNA. Translation: AAF51149.1. BT120005 mRNA. Translation: ACZ67868.1.
RefSeq	NP_647613.1. NM_139356.1.
UniGene	Dm.11974.
3D structure databases
HSSP	HSSP built from PDB template 1PQW based on UniProtKB P96202.
ProteinModelPortal	Q9VQL6.
SMR	Q9VQL6. Positions 15-869, 1447-1764, 1781-2013, 2024-2107, 2143-2405.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9VQL6.
Proteomic databases
PRIDE	Q9VQL6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0077657; FBpp0077342; FBgn0042627.
GeneID	117361.
KEGG	dme:Dmel_CG3524.
NMPDR	fig|7227.3.peg.533.
UCSC	CG3524-RA. d. melanogaster.
Organism-specific databases
CTD	117361.
FlyBase	FBgn0042627. v(2)k05816.
Phylogenomic databases
GeneTree	EMGT00050000005678.
InParanoid	Q9VQL6.
OMA	QWADNWI.
PhylomeDB	Q9VQL6.
Gene expression databases
ArrayExpress	Q9VQL6.
Bgee	Q9VQL6.
Family and domain databases
InterPro	IPR001227. Ac_transferase_dom. IPR009081. Acyl_carrier_prot-like. IPR014043. Acyl_transferase. IPR016035. Acyl_Trfase/lysoPLipase. IPR013149. ADH_C. IPR000794. Beta-ketoacyl_synthase. IPR002198. DH_sc/Rdtase_SDR. IPR011032. GroES-like. IPR018201. Ketoacyl_synth_AS. IPR014031. Ketoacyl_synth_C. IPR014030. Ketoacyl_synth_N. IPR016036. Malonyl_transacylase_ACP-bd. IPR016040. NAD(P)-bd_dom. IPR006163. Phsphopanteth-bd. IPR020842. PKS/FAS_KR. IPR020843. PKS_ER. IPR001031. Thioesterase. IPR016039. Thiolase-like. IPR016038. Thiolase-like_subgr. [Graphical view]
Gene3D	G3DSA:3.40.366.10. Ac_transferase_reg. 2 hits. G3DSA:1.10.1200.10. ACP_like. 1 hit. G3DSA:3.40.50.720. NAD(P)-bd. 2 hits. G3DSA:3.40.47.10. Thiolase-like_subgr. 2 hits.
KO	K00665.
PANTHER	PTHR11712. Ketoacyl_synth. 1 hit.
Pfam	PF00698. Acyl_transf_1. 1 hit. PF00106. adh_short. 1 hit. PF00107. ADH_zinc_N. 1 hit. PF00109. ketoacyl-synt. 1 hit. PF02801. Ketoacyl-synt_C. 1 hit. PF00550. PP-binding. 1 hit. PF00975. Thioesterase. 1 hit. [Graphical view]
SMART	SM00829. PKS_ER. 1 hit. SM00822. PKS_KR. 1 hit. [Graphical view]
SUPFAM	SSF47336. ACP_like. 1 hit. SSF52151. Acyl_Trfase/lysoPlipase. 1 hit. SSF50129. GroES_like. 1 hit. SSF55048. Malonyl_transacylase_ACP-bd. 1 hit. SSF53901. Thiolase-like. 1 hit.
PROSITE	PS50075. ACP_DOMAIN. 1 hit. PS00606. B_KETOACYL_SYNTHASE. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	841926.

Entry information

Entry name

Q9VQL6_DROME

Accession

Primary (citable) accession number: Q9VQL6

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	January 25, 2012
This is version 91 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)