Q9VQI9 (AFF4_DROME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
AF4/FMR2 family member 4

Alternative name(s):
Protein lilliputian
Suppressor of Raf at 2A
Suppressor of sina 2-1

Gene names

Name:	lilli
Synonyms:	l(2)00632, SS2-1, Su(Raf)2A
ORF Names:	CG8817

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1673 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Has a role in transcriptional regulation. Acts in parallel with the Ras/MAPK and the PI3K/PKB pathways in the control of cell identity and cellular growth. Essential for regulation of the cytoskeleton and cell growth but not for cell proliferation or growth rate. Required specifically for the microtubule-based basal transport of lipid droplets. Plays a partially redundant function downstream of Raf in cell fate specification in the developing eye. Pair-rule protein that regulates embryonic cellularization, gastrulation and segmentation. Ref.1 Ref.2 Ref.7 Ref.8 Ref.9
Subcellular location	Nucleus Ref.1.
Developmental stage	Expressed both maternally and zygotically. Ref.1 Ref.2
Disruption phenotype	Embryos lacking maternal lilli show specific defects in the establishment of a functional cytoskeleton during cellularization, and exhibit a pair-rule segmentation phenotype. Adults lacking lilli exhibit reduction in cell and organ size and partial suppression of the increased growth associated with loss of PTEN function. Ref.1 Ref.2
Sequence similarities	Belongs to the AF4 family. Contains 1 A.T hook DNA-binding domain.
Sequence caution	The sequence AAL28786.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. The sequence ACX54921.1 differs from that shown. Reason: Frameshift at position 1210.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Coding sequence diversity	Alternative splicing
Ligand	DNA-binding
Molecular function	Developmental protein Pair-rule protein
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	compound eye photoreceptor development Inferred from genetic interaction Ref.1. Source: FlyBase cytokinesis, actomyosin contractile ring assembly Non-traceable author statement. Source: FlyBase learning or memory Inferred from mutant phenotype. Source: FlyBase olfactory behavior Inferred from mutant phenotype. Source: FlyBase periodic partitioning by pair rule gene Inferred from mutant phenotype Ref.2. Source: UniProtKB regulation of cell size Inferred from mutant phenotype Ref.1. Source: FlyBase regulation of cytoskeleton organization Inferred from mutant phenotype Ref.2. Source: UniProtKB regulation of lipid transport Inferred from mutant phenotype Ref.2. Source: UniProtKB segment specification Inferred from mutant phenotype. Source: FlyBase transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW wing disc dorsal/ventral pattern formation Inferred from genetic interaction. Source: FlyBase
Cellular component	nucleus Inferred from direct assay Ref.1. Source: FlyBase
Molecular function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW sequence-specific DNA binding transcription factor activity Inferred from mutant phenotype Ref.2. Source: UniProtKB
Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform A Ref.3 (identifier: Q9VQI9-1)

Also known as: B; C; G;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform D Ref.3 (identifier: Q9VQI9-2)

Also known as: E; F;

The sequence of this isoform differs from the canonical sequence as follows:
     1-59: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1673	1673	AF4/FMR2 family member 4		PRO_0000394675
Regions
	DNA binding	851 – 863	13	A.T hook
	Compositional bias	3 – 48	46	Gln-rich
	Compositional bias	463 – 484	22	Ser-rich
	Compositional bias	489 – 525	37	Gln-rich
	Compositional bias	720 – 743	24	Ser-rich
	Compositional bias	941 – 1060	120	Ser-rich
Amino acid modifications
	Modified residue	420	1	Phosphothreonine Ref.10
	Modified residue	450	1	Phosphoserine Ref.10
	Modified residue	452	1	Phosphoserine Ref.10
	Modified residue	821	1	Phosphoserine Ref.10
	Modified residue	822	1	Phosphoserine Ref.10
	Modified residue	871	1	Phosphoserine Ref.10
	Modified residue	873	1	Phosphoserine Ref.10
	Modified residue	1362	1	Phosphoserine Ref.10
	Modified residue	1364	1	Phosphothreonine Ref.10
Natural variations
	Alternative sequence	1 – 59	59	Missing in isoform D. Ref.3		VSP_039294
Experimental info
	Sequence conflict	235	1	V → A in ACX54921. Ref.5
	Sequence conflict	254	1	L → M in ACX54921. Ref.5
	Sequence conflict	614	1	A → T in ACX54921. Ref.5
	Sequence conflict	1201	1	D → I in ACX54921. Ref.5

Sequences

	Sequence		Length	Mass (Da)
	Isoform A (B) (C) (G) [UniParc]. Last modified October 1, 2002. Version 2. Checksum: 7D32A4E81C55B752	FASTA	1,673	180,089
	10 20 30 40 50 60 MAQQQQQQMQ QQQQHHTSSI NNNNSSSIVL LQQQQPQQQQ QQLDQLQQYN NNLYSQNYNM 70 80 90 100 110 120 EEYERRKRRE REKIERQQGI QIDDRETSLF GEPRRLTEGD AEITAALGEF FEAREYINNQ 130 140 150 160 170 180 TVGISRSAPG AGNPRLQPNL APQAKSLGHS PSSASSAAGP TAASATTSLP GQQQHYQQQQ 190 200 210 220 230 240 RPPTYVKQAD NKPPYNGRGG YPGQPMKNDI PSSSGMAPPR GPPRTSSSNS NSSSVTNNAS 250 260 270 280 290 300 SGGVPASTPL GPPLSTQMPN GREKSFLGPP APALHNGTGG RFVPPAASKR PGVGQQPPPP 310 320 330 340 350 360 EKDVNKIISD IANIFTVQPL TLIAATPHAP TRENYNLLAP NRQKYAMDIP SSPPSAEPSS 370 380 390 400 410 420 LMTPLFAPIT SPIAPLVTTP PQASQMPLGG ATSGTILAGE ALAPLHQLPP TMPKAASGVT 430 440 450 460 470 480 SPGPVKPLKT EKNHSLEKQD SCLENDLELS ESEDEQRKKE GRSGGNSSNS SESDSSESGS 490 500 510 520 530 540 ESSSKNDLQH HPNHQQHHHQ LQQQQQQQQA TMQQQQVLQQ QHRSQPLTSN GAQNKKFRHE 550 560 570 580 590 600 IIARGSNTIT GLLSSSGFGS GGNVGPAGVN SNAVVGTGSG SGGTLSSGGS SSNKTPSPTE 610 620 630 640 650 660 SNKWNLSRFF HKPANQTNSE SVSPGNVSMK VPGILPGGAQ IIPESIDVTT AIVKNEKNDM 670 680 690 700 710 720 AMEEGEEEDD DEEQQLRYGG GLSVTPVAVK KEAIDAVSEM ALGAIPKTQI KRESAETLLS 730 740 750 760 770 780 ARLSDSGTSA SGSSSSSSSS SDSAMGGEVV PMPGPGETLQ LPGVPAAITT VMRVQPTQSQ 790 800 810 820 830 840 KAPPSNSVTL TPILPLPTSP KQRQKKPRKK KAITSAPILD SSDDDEPPPK HPGLDHTAVS 850 860 870 880 890 900 VQTQPATDTV KKGRGRPRKQ QQSGGSGNLS SASAGSSSQT KGPTLTAAKK PLAKTPLAMS 910 920 930 940 950 960 RARKREHSSQ SSSNGNTPTK KVATPQLVAA PLKPTSNTAG SSSSDEDSSS SAESSSKSSS 970 980 990 1000 1010 1020 SSSSSDDTET QNTNCRIVKL NKTGAVQKKA LLGSGSSSPS SSGSEAEDQT TRSQVGSGQA 1030 1040 1050 1060 1070 1080 LAQQLPPYKQ LPISQHSQHL SSSDCSSSSG GCTAVCSSSS GEEDEGRREK ERERKPKSDK 1090 1100 1110 1120 1130 1140 NKINTLTRIF NPKEGGAKKQ GQVVIVDLQE EQQQGKLDAA AQPSAPQAPP AAPAAIMAKP 1150 1160 1170 1180 1190 1200 RMTPTQQQQL GAGLASPART TTPHLTSLIC KIDLSKLSRE RIMRLKKLTP AQQNGHLTPK 1210 1220 1230 1240 1250 1260 DQATNAVHVP NGYAGDTNPA AKVKHEHPVK PEPELDAGYE AKFKPGNVKQ EFQLKQERDR 1270 1280 1290 1300 1310 1320 DRERERERER ERERDREREQ PPGRRRKRSS SSSSSPYKEK KRKKEKADQL QMGKELLPVP 1330 1340 1350 1360 1370 1380 VLLPSNNHER MPNHDRLSYD KLQLLHEDAA AVIGDVSAPN GSPTKKLLAM SPLPPPPTVT 1390 1400 1410 1420 1430 1440 VAPATCNEAV QTTPPSATAT SAIAPPVPAT RLIYRSYFDR DVEHPSDDPR KNNQFLQEAI 1450 1460 1470 1480 1490 1500 NRKHAADLER DSFNQVTLYL EAVVYFLLTA DAMERCSSEQ ATNTMYKDTL SLIKFISTKF 1510 1520 1530 1540 1550 1560 RPYQQQSTTN IQHETHNKVA ILSLRCQSLI SLKLYKLRRK DCRAIINSLT DFFRVGRGDI 1570 1580 1590 1600 1610 1620 ANGNTPSSIS PSNSVGSQGS GSNTPPGRIV PPDIHNMLCK QNEFLSYLNS AHELWDQADR 1630 1640 1650 1660 1670 LVRTGNHIDF IRELDHENGP LTLHSTMHEV FRYVQAGLKT LRDAVSHPTH QSQ
	Isoform D (E) (F) [UniParc]. Checksum: C8B04AF6642F9B4F	FASTA	1,614	173,034
	10 20 30 40 50 60 MEEYERRKRR EREKIERQQG IQIDDRETSL FGEPRRLTEG DAEITAALGE FFEAREYINN 70 80 90 100 110 120 QTVGISRSAP GAGNPRLQPN LAPQAKSLGH SPSSASSAAG PTAASATTSL PGQQQHYQQQ 130 140 150 160 170 180 QRPPTYVKQA DNKPPYNGRG GYPGQPMKND IPSSSGMAPP RGPPRTSSSN SNSSSVTNNA 190 200 210 220 230 240 SSGGVPASTP LGPPLSTQMP NGREKSFLGP PAPALHNGTG GRFVPPAASK RPGVGQQPPP 250 260 270 280 290 300 PEKDVNKIIS DIANIFTVQP LTLIAATPHA PTRENYNLLA PNRQKYAMDI PSSPPSAEPS 310 320 330 340 350 360 SLMTPLFAPI TSPIAPLVTT PPQASQMPLG GATSGTILAG EALAPLHQLP PTMPKAASGV 370 380 390 400 410 420 TSPGPVKPLK TEKNHSLEKQ DSCLENDLEL SESEDEQRKK EGRSGGNSSN SSESDSSESG 430 440 450 460 470 480 SESSSKNDLQ HHPNHQQHHH QLQQQQQQQQ ATMQQQQVLQ QQHRSQPLTS NGAQNKKFRH 490 500 510 520 530 540 EIIARGSNTI TGLLSSSGFG SGGNVGPAGV NSNAVVGTGS GSGGTLSSGG SSSNKTPSPT 550 560 570 580 590 600 ESNKWNLSRF FHKPANQTNS ESVSPGNVSM KVPGILPGGA QIIPESIDVT TAIVKNEKND 610 620 630 640 650 660 MAMEEGEEED DDEEQQLRYG GGLSVTPVAV KKEAIDAVSE MALGAIPKTQ IKRESAETLL 670 680 690 700 710 720 SARLSDSGTS ASGSSSSSSS SSDSAMGGEV VPMPGPGETL QLPGVPAAIT TVMRVQPTQS 730 740 750 760 770 780 QKAPPSNSVT LTPILPLPTS PKQRQKKPRK KKAITSAPIL DSSDDDEPPP KHPGLDHTAV 790 800 810 820 830 840 SVQTQPATDT VKKGRGRPRK QQQSGGSGNL SSASAGSSSQ TKGPTLTAAK KPLAKTPLAM 850 860 870 880 890 900 SRARKREHSS QSSSNGNTPT KKVATPQLVA APLKPTSNTA GSSSSDEDSS SSAESSSKSS 910 920 930 940 950 960 SSSSSSDDTE TQNTNCRIVK LNKTGAVQKK ALLGSGSSSP SSSGSEAEDQ TTRSQVGSGQ 970 980 990 1000 1010 1020 ALAQQLPPYK QLPISQHSQH LSSSDCSSSS GGCTAVCSSS SGEEDEGRRE KERERKPKSD 1030 1040 1050 1060 1070 1080 KNKINTLTRI FNPKEGGAKK QGQVVIVDLQ EEQQQGKLDA AAQPSAPQAP PAAPAAIMAK 1090 1100 1110 1120 1130 1140 PRMTPTQQQQ LGAGLASPAR TTTPHLTSLI CKIDLSKLSR ERIMRLKKLT PAQQNGHLTP 1150 1160 1170 1180 1190 1200 KDQATNAVHV PNGYAGDTNP AAKVKHEHPV KPEPELDAGY EAKFKPGNVK QEFQLKQERD 1210 1220 1230 1240 1250 1260 RDRERERERE RERERDRERE QPPGRRRKRS SSSSSSPYKE KKRKKEKADQ LQMGKELLPV 1270 1280 1290 1300 1310 1320 PVLLPSNNHE RMPNHDRLSY DKLQLLHEDA AAVIGDVSAP NGSPTKKLLA MSPLPPPPTV 1330 1340 1350 1360 1370 1380 TVAPATCNEA VQTTPPSATA TSAIAPPVPA TRLIYRSYFD RDVEHPSDDP RKNNQFLQEA 1390 1400 1410 1420 1430 1440 INRKHAADLE RDSFNQVTLY LEAVVYFLLT ADAMERCSSE QATNTMYKDT LSLIKFISTK 1450 1460 1470 1480 1490 1500 FRPYQQQSTT NIQHETHNKV AILSLRCQSL ISLKLYKLRR KDCRAIINSL TDFFRVGRGD 1510 1520 1530 1540 1550 1560 IANGNTPSSI SPSNSVGSQG SGSNTPPGRI VPPDIHNMLC KQNEFLSYLN SAHELWDQAD 1570 1580 1590 1600 1610 RLVRTGNHID FIRELDHENG PLTLHSTMHE VFRYVQAGLK TLRDAVSHPT HQSQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lilliputian: an AF4/FMR2-related protein that controls cell identity and cell growth." Wittwer F., van der Straten A., Keleman K., Dickson B.J., Hafen E. Development 128:791-800(2001) [PubMed: 11171403] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A), FUNCTION, SUBCELLULAR LOCATION, DEVELOPMENTAL STAGE, DISRUPTION PHENOTYPE.
[2]	"Transcriptional regulation of cytoskeletal functions and segmentation by a novel maternal pair-rule gene, lilliputian." Tang A.H., Neufeld T.P., Rubin G.M., Muller H.A. Development 128:801-813(2001) [PubMed: 11171404] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A), FUNCTION, DEVELOPMENTAL STAGE, DISRUPTION PHENOTYPE.
[3]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[4]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: GENOME REANNOTATION, ALTERNATIVE SPLICING. Strain: Berkeley.
[5]	Carlson J.W., Booth B., Frise E., Park S., Wan K.H., Yu C., Celniker S.E. Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM D). Strain: Berkeley. Tissue: Testis.
[6]	"A Drosophila full-length cDNA resource." Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A., Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M., Celniker S.E. Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002) [PubMed: 12537569] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1374-1673 (ISOFORMS A/D). Strain: Berkeley. Tissue: Embryo.
[7]	"Mutations Modulating Raf signaling in Drosophila eye development." Dickson B.J., van der Straten A., Dominguez M., Hafen E. Genetics 142:163-171(1996) [PubMed: 8770593] [Abstract] Cited for: FUNCTION.
[8]	"Zygotic lethal mutations with maternal effect phenotypes in Drosophila melanogaster. II. Loci on the second and third chromosomes identified by P-element-induced mutations." Perrimon N., Lanjuin A., Arnold C., Noll E. Genetics 144:1681-1692(1996) [PubMed: 8978055] [Abstract] Cited for: FUNCTION.
[9]	"A genetic screen to identify components of the sina signaling pathway in Drosophila eye development." Neufeld T.P., Tang A.H., Rubin G.M. Genetics 148:277-286(1998) [PubMed: 9475739] [Abstract] Cited for: FUNCTION.
[10]	"Phosphoproteome analysis of Drosophila melanogaster embryos." Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P. J. Proteome Res. 7:1675-1682(2008) [PubMed: 18327897] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-420; SER-450; SER-452; SER-821; SER-822; SER-871; SER-873; SER-1362 AND THR-1364, MASS SPECTROMETRY. Tissue: Embryo.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF293971 mRNA. Translation: AAG53639.1. AF289034 mRNA. Translation: AAK18163.1. AE014134 Genomic DNA. Translation: AAF51180.2. AE014134 Genomic DNA. Translation: AAN10399.1. AE014134 Genomic DNA. Translation: AAN10400.1. AE014134 Genomic DNA. Translation: ACL82979.1. AE014134 Genomic DNA. Translation: ACL82980.1. AE014134 Genomic DNA. Translation: ACL82981.1. AE014134 Genomic DNA. Translation: ACL82982.1. BT100013 mRNA. Translation: ACX54921.1. Frameshift. AY061238 mRNA. Translation: AAL28786.1. Different initiation.
RefSeq	NP_001137772.1. NM_001144300.1. NP_001137773.1. NM_001144301.1. NP_001137774.1. NM_001144302.1. NP_001137775.1. NM_001144303.1. NP_523464.1. NM_078740.2. NP_722863.1. NM_164516.1. NP_722864.1. NM_164517.1.
UniGene	Dm.2778.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9VQI9. 1 interaction.
MINT	MINT-1011233.
STRING	Q9VQI9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0077632; FBpp0077317; FBgn0041111. FBtr0077633; FBpp0077318; FBgn0041111. FBtr0077634; FBpp0077319; FBgn0041111. FBtr0290041; FBpp0288480; FBgn0041111.
GeneID	33496.
KEGG	dme:Dmel_CG8817.
UCSC	CG8817-RA. d. melanogaster.
Organism-specific databases
CTD	33496.
FlyBase	FBgn0041111. lilli.
Phylogenomic databases
GeneTree	EMGT00050000000303.
InParanoid	Q9VQI9.
OMA	CLENDLE.
OrthoDB	EOG4XGXDZ.
PhylomeDB	Q9VQI9.
Gene expression databases
ArrayExpress	Q9VQI9.
Bgee	Q9VQI9.
Family and domain databases
InterPro	IPR017956. AT_hook_DNA-bd_motif. IPR007797. TF_AF4/FMR2. [Graphical view]
KO	K15194.
PANTHER	PTHR10528. AF-4. 1 hit.
Pfam	PF05110. AF-4. 1 hit. [Graphical view]
SMART	SM00384. AT_hook. 1 hit. [Graphical view]
PROSITE	PS00354. HMGI_Y. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	783881.

Entry information

Entry name

AFF4_DROME

Accession

Primary (citable) accession number: Q9VQI9
Secondary accession number(s): B7YZZ6 , C9QPD1, Q95RP2, Q9BH66

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 15, 2010
Last sequence update:	October 1, 2002
Last modified:	January 25, 2012
This is version 82 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Drosophila annotation project