Unreviewed, UniProtKB/TrEMBL Q9VQF4 (Q9VQF4_DROME)

Names and origin

Protein names

Recommended name:
    Phosphoglycerate kinase RuleBase RU000532V2
    EC=2.7.2.3

Gene names

ORF Names:

CG9961 FlyBase FBgn0031451, Dmel_CG9961 EMBL AAF51220.2

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	448 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. RuleBase RU000532V2
Subunit structure	Monomer By similarity. RuleBase RU000696V2
Sequence similarities	Belongs to the phosphoglycerate kinase family. RuleBase RU000532V2

Ontologies

Keywords
Molecular function	Kinase RuleBase RU000532V2 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: InterPro
Molecular function	phosphoglycerate kinase activity Inferred from electronic annotation. Source: EC protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
ade2	P35421	1	EBI-122086,EBI-89279
rtet	Q9V395	1	EBI-122086,EBI-184706

Sequences

	Sequence		Length	Mass (Da)
	Q9VQF4-1 [UniParc]. Last modified October 1, 2002. Version 2. Checksum: D13FC6CE846BA3D1	FASTA	448	48,561
	10 20 30 40 50 60 MLPIRQSLYQ RAQTRFTKLR FPRFFSKDDC NGKQVKKLSL KNVDVAGKRV FMRVDFNVPM 70 80 90 100 110 120 KDGKITNNQR IVSALPSIKY ALDKKCKSLV LASHLGRPDG KKNKKFSLEP VAKELESVLG 130 140 150 160 170 180 QPVQFLDDCV GDSTLRALKD PSDGTVFLLE NLRFYAEETG SSKDDNKKKV KADPAKVKEF 190 200 210 220 230 240 RAKLAQLGEI YVNDAFGTAH RPHSSMMGDG YKVRAAGFLL DKELEYFAKV LHDPAKPFLA 250 260 270 280 290 300 ILGGAKIADK IPLITNLLNN VTAMIISGGM AFTFLKVLNG MEIGKSLFDE KGSELVNDIV 310 320 330 340 350 360 CKAKEKDVNI LFPIDFVIAN KIDKEPDKVE HVDATQGIPE DMMGLDHGQA SSQMFAGAIC 370 380 390 400 410 420 ASKTIVWNGP PGLFENELFS KGTESMLEAV IGATNRGATT IVGGGDTATA CLKFGGADKV 430 440 SHVSTGGGAS LELLEGKVLP GVAALSDA

References

[1]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014134 Genomic DNA. Translation: AAF51220.2.
RefSeq	NP_608704.2.
UniGene	Dm.5077
3D structure databases
HSSP	HSSP built from PDB template 1QPG based on UniProtKB P00560.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9VQF4. 2 interactions.
STRING	Q9VQF4.
Genome annotation databases
Ensembl	FBtr0077740; FBpp0077420; FBgn0031451; Drosophila melanogaster. [Genome view]
GeneID	33459.
KEGG	dme:Dmel_CG9961.
NMPDR	fig|7227.3.peg.438.
UCSC	CG9961-RA. d. melanogaster.
Organism-specific databases
FlyBase	FBgn0031451. CG9961.
Phylogenomic databases
OMA	GAICASK
OrthoDB	EOG9VDQ6F
PhylomeDB	Q9VQF4.
Gene expression databases
ArrayExpress	Q9VQF4.
Family and domain databases
HAMAP	MF_00145. [Tree]
InterPro	IPR001576. Phosphoglycerate_kinase. IPR015901. Phosphoglycerate_kinase_C. IPR015911. Phosphoglycerate_kinase_CS. IPR015824. Phosphoglycerate_kinase_N. [Graphical view]
Gene3D	G3DSA:3.40.50.1270. Phosphoglycerate_kinase_C. 1 hit. G3DSA:3.40.50.1260. Phosphoglycerate_kinase_N. 1 hit.
PANTHER	PTHR11406. PGK. 1 hit.
Pfam	PF00162. PGK. 1 hit. [Graphical view]
PRINTS	PR00477. PHGLYCKINASE.
PROSITE	PS00111. PGLYCERATE_KINASE. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	783678.

Entry information

Entry name

Q9VQF4_DROME

Accession

Primary (citable) accession number: Q9VQF4

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	October 1, 2002
Last modified:	November 24, 2009
This is version 61 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)