Unreviewed, UniProtKB/TrEMBL Q9VQE0 (Q9VQE0_DROME)

Names and origin

Protein names

Submitted name:
    Dynamin related protein 1 EMBL AAF51235.1

Gene names

Name:	Drp1 EMBL AAF51235.1
ORF Names:	Dmel_CG3210 EMBL AAF51235.1

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	735 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the dynamin family. RuleBase RU003932V0 Contains 1 GED domain. Spearmint SPM019762

Ontologies

Keywords
Ligand	GTP-binding RuleBase RU003932V0 Spearmint SPM000375 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cytokinesis Inferred from mutant phenotype. Source: FlyBase sperm mitochondrion organization Inferred from mutant phenotype. Source: FlyBase synaptic vesicle budding from presynaptic membrane Non-traceable author statement. Source: FlyBase
Molecular function	GTP binding Inferred from electronic annotation. Source: InterPro GTPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VQE0-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 7D4961D0352D8642	FASTA	735	82,566
	10 20 30 40 50 60 MEALIPVINK LQDVFNTVGS DSIQLPQIVV LGSQSSGKSS VIESVVGRSF LPRGTGIVTR 70 80 90 100 110 120 RPLVLQLIYS PLDDRENRSA ENGTSNAEEW GRFLHTKKCF TDFDEIRKEI ENETERAAGS 130 140 150 160 170 180 NKGICPEPIN LKIFSTHVVN LTLVDLPGIT KVPVGDQPED IEAQIKELVL KYIENPNSII 190 200 210 220 230 240 LAVTAANTDM ATSEALKLAK DVDPDGRRTL AVVTKLDLMD AGTDAIDILC GRVIPVKLGI 250 260 270 280 290 300 IGVMNRSQKD IMDQKHIDDQ MKDEAAFLQR KYPTLATRNG TPYLAKTLNR LLMHHIRDCL 310 320 330 340 350 360 PDLKTRVNIM ATQFQSLLNS YGEDVSDKSQ TLLQIITKFS SAYCCTIEGT ARNIETTELC 370 380 390 400 410 420 GGARMGYIFH ETFGRTLDSI HPLAGLSKMD ILTAIRNATG PRPALFVPEV SFELLVKRQI 430 440 450 460 470 480 RRLEEPSLRC VELIHEEMQR IVQHCGNEVQ QEMLRFPKLH EKIVDVVTQL LRRRLPHTNV 490 500 510 520 530 540 MVENIVAIEL AYINTKHPDF HKDAALVPSL LKTDSDPYSQ INLGQRRANT PRNHMSPQIS 550 560 570 580 590 600 SHSAGSQQPQ QQQPPQPNSS QQQYSQVHEQ NHVAENSTPS MASTWLSNIL PPAPTRPDSI 610 620 630 640 650 660 ENSTNNTPVH NNIVSPVKPV NLLPDVPANH NPRRLTDKEQ KDCDVIEHLI KSYFYIVRKS 670 680 690 700 710 720 IQDSVPKAIM HFLVNYVKDN LQSELVTHLY KSDKAETLLN ESDHIAVRRK EAADMLKALT 730 RANHIISEIR ETHMW

References

[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014134 Genomic DNA. Translation: AAF51235.1.
RefSeq	NP_608694.2.
UniGene	Dm.272
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9VQE0. 10 interactions.
Proteomic databases
PRIDE	Q9VQE0.
Genome annotation databases
Ensembl	FBgn0026479. Drosophila melanogaster. [Contig view]
GeneID	33445.
KEGG	dme:Dmel_CG3210.
NMPDR	fig|7227.3.peg.417.
Organism-specific databases
FlyBase	FBgn0026479. Drp1.
Phylogenomic databases
OMA	Q9VQE0. NDPATWK.
Gene expression databases
ArrayExpress	Q9VQE0.
Family and domain databases
InterPro	IPR000375. Dynamin_central. IPR001401. Dynamin_GTPase. IPR019762. Dynamin_GTPase_CS. IPR003130. GED. [Graphical view]
Pfam	PF01031. Dynamin_M. 1 hit. PF00350. Dynamin_N. 1 hit. PF02212. GED. 1 hit. [Graphical view]
PRINTS	PR00195. DYNAMIN.
SMART	SM00053. DYNc. 1 hit. SM00302. GED. 1 hit. [Graphical view]
PROSITE	PS00410. DYNAMIN. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	783610.

Entry information

Entry name

Q9VQE0_DROME

Accession

Primary (citable) accession number: Q9VQE0

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	June 16, 2009
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)