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Q9VQ08

- Q9VQ08_DROME

UniProt

Q9VQ08 - Q9VQ08_DROME

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Protein
Submitted name: FI23903p1
Gene
lea, lea-RA, CG5481, Dmel_CG5481
Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. protein homodimerization activity Source: FlyBase
  2. receptor activity Source: FlyBase
Complete GO annotation...

GO - Biological processi

  1. axon guidance Source: FlyBase
  2. cardioblast cell fate specification Source: FlyBase
  3. central complex development Source: FlyBase
  4. embryonic heart tube development Source: FlyBase
  5. gonad development Source: FlyBase
  6. mushroom body development Source: FlyBase
  7. neuron migration Source: FlyBase
  8. outflow tract morphogenesis Source: FlyBase
  9. positive regulation of cell-cell adhesion Source: FlyBase
  10. regulation of epithelial cell migration, open tracheal system Source: FlyBase
  11. salivary gland boundary specification Source: FlyBase
  12. synaptic target recognition Source: FlyBase
  13. tracheal outgrowth, open tracheal system Source: FlyBase
  14. ventral cord development Source: FlyBase
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
FI23903p1Imported
Submitted name:
Leak, isoform AImported
Gene namesi
Name:leaImported
Synonyms:lea-RAImported
ORF Names:CG5481Imported, Dmel_CG5481Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000000803: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0002543. lea.

Subcellular locationi

GO - Cellular componenti

  1. axon Source: FlyBase
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ9VQ08.

Interactioni

Protein-protein interaction databases

MINTiMINT-788772.

Family & Domainsi

Keywords - Domaini

RepeatSAAS annotations

Phylogenomic databases

GeneTreeiENSGT00720000108572.
InParanoidiQ9VQ08.

Family and domain databases

Gene3Di2.60.40.10. 9 hits.
InterProiIPR003961. Fibronectin_type3.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
[Graphical view]
PfamiPF00041. fn3. 2 hits.
PF07679. I-set. 4 hits.
[Graphical view]
SMARTiSM00060. FN3. 3 hits.
SM00409. IG. 1 hit.
SM00408. IGc2. 4 hits.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 3 hits.
PROSITEiPS50853. FN3. 3 hits.
PS50835. IG_LIKE. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9VQ08-1 [UniParc]FASTAAdd to Basket

« Hide

MHLCEMRGMP LRLQPQCLTN ESEIQIKIKS KIKNKTASEI KRRHRNNRDF     50
HGERLKIMPV DRSRRAVFPL LLLLAGLNGL TQVGALKGEN PRIIEHPMDT 100
TVPKNDPFTF NCQAEGNPTP TIQWFKDGRE LKTDTGSHRI MLPAGGLFFL 150
KVIHSRRESD AGTYWCEAKN EFGVARSRNA TLQVAFLRDE FRLEPANTRV 200
AQGEVALMEC GAPRGSPEPQ ISWRKNGQTL NLVGNKRIRI VDGGNLAIQE 250
ARQSDDGRYQ CVVKNVVGTR ESATAFLKVH VRPFLIRGPQ NQTAVVGSSV 300
VFQCRIGGDP LPDVLWRRTA SGGNMPLRRV HVLEDRSLKL DDVTLEDMGE 350
YTCEADNAVG GITATGILTV HAPPKFVIRP KNQLVEIGDE VLFECQANGH 400
PRPTLYWSVE GNSSLLLPGY RDGRMEVTLT PEGRSVLSIA RFAREDSGKV 450
VTCNALNAVG SVSSRTVVSV DTQFELPPPI IEQGPVNQTL PVKSIVVLPC 500
RTLGTPVPQV SWYLDGIPID VQEHERRNLS DAGALTISDL QRHEDEGLYT 550
CVASNRNGKS SWSGYLRLDT PTNPNIKFFR APELSTYPGP PGKPQMVEKG 600
ENSVTLSWTR SNKVGGSSLV GYVIEMFGKN ETDGWVAVGT RVQNTTFTQT 650
GLLPGVNYFF LIRAENSHGL SLPSPMSEPI TVGTRYFNSG LDLSEARASL 700
LSGDVVELSN ASVVDSTSMK LTWQIINGKY VEGFYVYARQ LPNPIVNNPA 750
PVTSNTNPLL GSTSTSASAS ASASALISTK PNIAAAGKRD GETNQSGGGA 800
PTPLNTKYRM LTILNGGGAS SCTITGLVQY TLYEFFIVPF YKSVEGKPSN 850
SRIARTLEDV PSEAPYGMEA LLLNSSAVFL KWKAPELKDR HGVLLNYHVI 900
VRGIDTAHNF SRILTNVTID AASPTLVLAN LTEGVMYTVG VAAGNNAGVG 950
PYCVPATLRL DPITKRLDPF INQRYPINQD HVNDVLTQPW FIILLGAILA 1000
VLMLSFGAMV FVKRKHMMMK QSALNTMRGN HTSDVLKMPS LSARNGNGYW 1050
LDSSTGGMVW RPSPGGDSLE MQKDHIADYA PVCGAPGSPA GGGTSSGGSG 1100
GAGSGASGGD DIHGGHGSER NQQRYVGEYS NIPTDYAEVS SFGKAPSEYG 1150
RHGNASPAPY ATSSILSPHQ QQQQQQPRYQ QRPVPGYGLQ RPMHPHYQQQ 1200
QHQQQQAQQT HQQHQALQQH QQLPPSNIYQ QMSTTSEIYP TNTGPSRSVY 1250
SEQYYYPKDK QRHIHITENK LSNCHTYEAA PGAKQSSPIS SQFASVRRQQ 1300
LPPNCSIGRE SARFKVLNTD QGKNQQNLLD LDGSSMCYNG LADSGCGGSP 1350
SPMAMLMSHE DEHALYHTAD GDLDDMERLY VKVDEQQPPQ QQQQLIPLVP 1400
QHPAEGHLQS WRNQSTRSSR KNGQECIKEP SELIYAPGSV ASERSLLSNS 1450
GSGTSSQPAG HNV 1463
Length:1,463
Mass (Da):159,977
Last modified:October 1, 2002 - v2
Checksum:i177A21647E6BD5A9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014134 Genomic DNA. Translation: AAF51375.2.
BT150394 mRNA. Translation: AHA59284.1.
RefSeqiNP_536792.2. NM_080531.3.
UniGeneiDm.1441.

Genome annotation databases

EnsemblMetazoaiFBtr0077941; FBpp0077606; FBgn0002543.
GeneIDi44522.
KEGGidme:Dmel_CG5481.
UCSCiCG5481-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014134 Genomic DNA. Translation: AAF51375.2 .
BT150394 mRNA. Translation: AHA59284.1 .
RefSeqi NP_536792.2. NM_080531.3.
UniGenei Dm.1441.

3D structure databases

ModBasei Search...

Protein-protein interaction databases

MINTi MINT-788772.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0077941 ; FBpp0077606 ; FBgn0002543 .
GeneIDi 44522.
KEGGi dme:Dmel_CG5481.
UCSCi CG5481-RA. d. melanogaster.

Organism-specific databases

CTDi 44522.
FlyBasei FBgn0002543. lea.

Phylogenomic databases

GeneTreei ENSGT00720000108572.
InParanoidi Q9VQ08.

Miscellaneous databases

GenomeRNAii 44522.
NextBioi 837362.

Gene expression databases

Bgeei Q9VQ08.

Family and domain databases

Gene3Di 2.60.40.10. 9 hits.
InterProi IPR003961. Fibronectin_type3.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
[Graphical view ]
Pfami PF00041. fn3. 2 hits.
PF07679. I-set. 4 hits.
[Graphical view ]
SMARTi SM00060. FN3. 3 hits.
SM00409. IG. 1 hit.
SM00408. IGc2. 4 hits.
[Graphical view ]
SUPFAMi SSF49265. SSF49265. 3 hits.
PROSITEi PS50853. FN3. 3 hits.
PS50835. IG_LIKE. 5 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Drosophila melanogaster."
    Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
    , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
    Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  3. Cited for: GENOME REANNOTATION.
    Strain: Berkeley.
  4. "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective."
    Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M., Celniker S.E.
    Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  5. "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly."
    Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., Karpen G.H.
    Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  6. "Combined evidence annotation of transposable elements in genome sequences."
    Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., Ashburner M., Anxolabehere D.
    PLoS Comput. Biol. 1:166-175(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  7. Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S., Svirskas R., Rubin G.
    Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  8. "Drosophila melanogaster release 4 sequence."
    Berkeley Drosophila Genome Project
    Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., Yu C., Rubin G.
    Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  9. "The Release 5.1 annotation of Drosophila melanogaster heterochromatin."
    Smith C.D., Shu S., Mungall C.J., Karpen G.H.
    Science 316:1586-1591(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  10. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  11. Carlson J., Booth B., Frise E., Park S., Wan K., Yu C., Celniker S.
    Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  12. FlyBase
    Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9VQ08_DROME
AccessioniPrimary (citable) accession number: Q9VQ08
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: October 1, 2002
Last modified: June 11, 2014
This is version 117 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi