Unreviewed, UniProtKB/TrEMBL Q9VPR4 (Q9VPR4_DROME)

Names and origin

Protein names

Submitted name:
    Notchless EMBL AAF51479.2
Submitted name:
    AT08344p EMBL AAL90024.1

Gene names

Name:	Nle EMBL AAF51479.2
ORF Names:	CG2863 FlyBase FBgn0021874, Dmel_CG2863 EMBL AAF51479.2

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	488 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Cellular component	Nucleus Spearmint SPM012972
Domain	Repeat Spearmint SPM001632 RuleBase RU003532V3 WD repeat Spearmint SPM001632 RuleBase RU000362V4
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	Notch signaling pathway Traceable author statement. Source: FlyBase
Molecular function	Notch binding Traceable author statement. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VPR4-1 [UniParc]. Last modified July 5, 2004. Version 2. Checksum: D4883202954A7785	FASTA	488	53,810
	10 20 30 40 50 60 MLAKKQKMQE TDTEQEATPH TIQARLVSDT GEEAGPPIDL PAGITTQQLG LICNALLKNE 70 80 90 100 110 120 EATPYLFFVG EDEIKKSLED TLDLASVDTE NVIDIVYQPQ AVFKVRPVTR CTSSMPGHAE 130 140 150 160 170 180 AVVSLNFSPD GAHLASGSGD TTVRLWDLNT ETPHFTCTGH KQWVLCVSWA PDGKRLASGC 190 200 210 220 230 240 KAGSIIIWDP ETGQQKGRPL SGHKKHINCL AWEPYHRDPE CRKLASASGD GDCRIWDVKL 250 260 270 280 290 300 GQCLMNIAGH TNAVTAVRWG GAGLIYTSSK DRTVKMWRAA DGILCRTFSG HAHWVNNIAL 310 320 330 340 350 360 STDYVLRTGP FHPVKDRSKS HLSLSTEELQ ESALKRYQAV CPDEVESLVS CSDDNTLYLW 370 380 390 400 410 420 RNNQNKCVER MTGHQNVVND VKYSPDVKLI ASASFDKSVR LWRASDGQYM ATFRGHVQAV 430 440 450 460 470 480 YTVAWSADSR LIVSGSKDST LKVWSVQTKK LAQELPGHAD EVFGVDWAPD GSRVASGGKD KVIKLWAY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014134 Genomic DNA. Translation: AAF51479.2. AY089286 mRNA. Translation: AAL90024.1.
RefSeq	NP_477294.2.
UniGene	Dm.13475
3D structure databases
HSSP	HSSP built from PDB template 1ERJ based on UniProtKB P16649.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9VPR4. 1 interaction.
Genome annotation databases
Ensembl	FBgn0021874. Drosophila melanogaster. [Contig view]
GeneID	33234.
KEGG	dme:Dmel_CG2863.
NMPDR	fig|7227.3.peg.120.
Organism-specific databases
FlyBase	FBgn0021874. Nle.
Phylogenomic databases
HOGENOM	Q9VPR4.
OMA	Q9VPR4. KGHRHWV.
Gene expression databases
ArrayExpress	Q9VPR4.
Family and domain databases
InterPro	IPR001632. Gprotein_B. IPR012972. NLE. IPR015943. WD40/YVTN_repeat-like. IPR001680. WD40_repeat. IPR019782. WD40_repeat_2. IPR019775. WD40_repeat_CS. IPR017986. WD40_repeat_region. IPR019781. WD40_repeat_sg. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 2 hits.
Pfam	PF08154. NLE. 1 hit. PF00400. WD40. 8 hits. [Graphical view]
PRINTS	PR00319. GPROTEINB.
ProDom	PD000018. WD40. 7 hits. [Graphical view] [Entries sharing at least one domain]
SMART	SM00320. WD40. 8 hits. [Graphical view]
PROSITE	PS00678. WD_REPEATS_1. 2 hits. PS50082. WD_REPEATS_2. 7 hits. PS50294. WD_REPEATS_REGION. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	782583.

Entry information

Entry name

Q9VPR4_DROME

Accession

Primary (citable) accession number: Q9VPR4
Secondary accession number(s): Q8T4A2

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	July 5, 2004
Last modified:	July 7, 2009
This is version 69 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)