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Protein

60S ribosomal protein L13a

Gene

RpL13A

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • mRNA binding Source: GO_Central
  • structural constituent of ribosome Source: FlyBase

GO - Biological processi

  • chaeta morphogenesis Source: FlyBase
  • cytoplasmic translation Source: FlyBase
  • Notch signaling pathway Source: FlyBase

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-DME-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DME-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DME-72689. Formation of a pool of free 40S subunits.
R-DME-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DME-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DME-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L13a
Gene namesi
Name:RpL13A
ORF Names:CG1475
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0037351. RpL13A.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001337761 – 20560S ribosomal protein L13aAdd BLAST205

Proteomic databases

PaxDbiQ9VNE9.
PRIDEiQ9VNE9.

Expressioni

Gene expression databases

BgeeiFBgn0037351.
ExpressionAtlasiQ9VNE9. differential.
GenevisibleiQ9VNE9. DM.

Interactioni

Protein-protein interaction databases

BioGridi65893. 27 interactors.
DIPiDIP-19002N.
IntActiQ9VNE9. 19 interactors.
MINTiMINT-790225.
STRINGi7227.FBpp0078354.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4V6Welectron microscopy6.00CO1-205[»]
ProteinModelPortaliQ9VNE9.
SMRiQ9VNE9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3204. Eukaryota.
COG0102. LUCA.
GeneTreeiENSGT00390000010799.
InParanoidiQ9VNE9.
KOiK02872.
OMAiKHNREMK.
OrthoDBiEOG091G0PUZ.
PhylomeDBiQ9VNE9.

Family and domain databases

CDDicd00392. Ribosomal_L13. 1 hit.
Gene3Di3.90.1180.10. 1 hit.
HAMAPiMF_01366. Ribosomal_L13. 1 hit.
InterProiView protein in InterPro
IPR005822. Ribosomal_L13.
IPR023563. Ribosomal_L13_CS.
IPR005755. Ribosomal_L13_euk/arc.
PANTHERiPTHR11545. PTHR11545. 1 hit.
PTHR11545:SF8. PTHR11545:SF8. 1 hit.
PfamiView protein in Pfam
PF00572. Ribosomal_L13. 1 hit.
PIRSFiPIRSF002181. Ribosomal_L13. 1 hit.
SUPFAMiSSF52161. SSF52161. 1 hit.
TIGRFAMsiTIGR01077. L13_A_E. 1 hit.
PROSITEiView protein in PROSITE
PS00783. RIBOSOMAL_L13. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9VNE9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGLTNRTVV IDGRGHLLGR LASVVAKYLL QGGKVAVVRC EELNLSGHFY
60 70 80 90 100
RNKIKFLAYL RKRCNVNPAR GPFHFRAPSR IFYKAVRGMI PHKTKRGQAA
110 120 130 140 150
LARLRVFDGI PSPYDKRRRV VVPIAMRVLT LRSDRKYCQV GRLSHEVGWH
160 170 180 190 200
YQDVIKSLER KRKAKLRVTL KHNRELKKLT VKARENIAKA AEPFNKIIKS

YGYEV
Length:205
Mass (Da):23,647
Last modified:May 1, 2000 - v1
Checksum:iCB4D1C6B97E079EE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAF51987.1.
AY051640 mRNA. Translation: AAK93064.1.
RefSeqiNP_649560.1. NM_141303.3.
UniGeneiDm.4531.

Genome annotation databases

EnsemblMetazoaiFBtr0078705; FBpp0078354; FBgn0037351.
GeneIDi40687.
KEGGidme:Dmel_CG1475.

Similar proteinsi

Entry informationi

Entry nameiRL13A_DROME
AccessioniPrimary (citable) accession number: Q9VNE9
Secondary accession number(s): Q9VNF0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2003
Last sequence update: May 1, 2000
Last modified: September 27, 2017
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families