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Protein

ATP-dependent RNA helicase SUV3 homolog, mitochondrial

Gene

CG9791

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

ATPase and DNA/RNA helicase able to unwind DNA/DNA, DNA/RNA and RNA/RNA duplexes in the 5'-3' direction.By similarity

Catalytic activityi

ATP + H2O = ADP + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi194 – 201ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

  • DNA duplex unwinding Source: UniProtKB
  • mitochondrial mRNA polyadenylation Source: FlyBase
  • mitochondrial RNA processing Source: FlyBase
  • mitochondrial tRNA processing Source: FlyBase
  • oxidative phosphorylation Source: FlyBase
  • positive regulation of mitochondrial translation Source: FlyBase
  • regulation of mitochondrial mRNA stability Source: FlyBase
  • respiratory electron transport chain Source: FlyBase
  • RNA catabolic process Source: GO_Central

Keywordsi

Molecular functionHelicase, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ATP-dependent RNA helicase SUV3 homolog, mitochondrial (EC:3.6.4.13)
Gene namesi
ORF Names:CG9791
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0037232. CG9791.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial degradosome Source: GO_Central
  • mitochondrial matrix Source: UniProtKB
  • mitochondrion Source: FlyBase
  • nucleus Source: UniProtKB-SubCell

Keywords - Cellular componenti

Mitochondrion, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 43MitochondrionSequence analysisAdd BLAST43
ChainiPRO_000031055244 – 763ATP-dependent RNA helicase SUV3 homolog, mitochondrialAdd BLAST720

Proteomic databases

PaxDbiQ9VN03.
PRIDEiQ9VN03.

Expressioni

Gene expression databases

BgeeiFBgn0037232.
ExpressionAtlasiQ9VN03. differential.
GenevisibleiQ9VN03. DM.

Interactioni

Protein-protein interaction databases

BioGridi65764. 1 interactor.
IntActiQ9VN03. 2 interactors.
MINTiMINT-1742266.
STRINGi7227.FBpp0271517.

Structurei

3D structure databases

ProteinModelPortaliQ9VN03.
SMRiQ9VN03.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini181 – 321Helicase ATP-bindingPROSITE-ProRule annotationAdd BLAST141
Domaini330 – 508Helicase C-terminalPROSITE-ProRule annotationAdd BLAST179

Sequence similaritiesi

Belongs to the helicase family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG0953. Eukaryota.
ENOG410XSEY. LUCA.
GeneTreeiENSGT00390000003100.
InParanoidiQ9VN03.
KOiK17675.
OMAiADMIQHI.
OrthoDBiEOG091G02NO.
PhylomeDBiQ9VN03.

Family and domain databases

InterProiView protein in InterPro
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR022192. SUV3_C.
PfamiView protein in Pfam
PF00271. Helicase_C. 1 hit.
PF12513. SUV3_C. 1 hit.
SMARTiView protein in SMART
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiView protein in PROSITE
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9VN03-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQNCRRCISL TGLLRMTLYL RPSFSIDLSL RRLHRAAFLF SRKKPETNLS
60 70 80 90 100
TLFKPVQVHA YVDSEDVGSE LSGKLEKAEL LKILNKFTQR REIKSLCNEN
110 120 130 140 150
GLDDYLQQQA FGSFRRFCIE AENLPVDLHI TFSDITQGAG HIDDIFPYFL
160 170 180 190 200
RHAKTVFPHL DCMDDLKKIS DLRQPANWYS NARAITRKIV FHAGPTNSGK
210 220 230 240 250
TYHAMERYLS AKTGVYCGPL KLLATEVYNK ANERGTPCDL VTGEERKFGI
260 270 280 290 300
SESLPANHVA CTVEMTSVNT PYEVAVIDEI QQIRDPQRGW AWTRAFLGLI
310 320 330 340 350
ADEVHVCGEP GALDLLQKIC ETTGETVEVR LYDRLTELTV ENTALGSLDN
360 370 380 390 400
IVPGDCIVCF SKHDIYTVSR EIEARGKEVA VIYGGLPPGT KLAQAAKFND
410 420 430 440 450
PANSCKVMVA TDAIGMGLNL SIRRIIFYSL IKPSMNERGE REIDTISVSS
460 470 480 490 500
ALQIAGRAGR FRTQWEHGYV TAFKSEDLQT LQRILARTPE PIKQAGLHPT
510 520 530 540 550
ADQIELYAYH LPSSSLSNLM DIFVNLCTVD DSLYFMCNIE DFKFLAEMIQ
560 570 580 590 600
HVALPLRARY VFCCAPINRK MPFVCSMFLK VARQYSRNEP ITFDFIKKNC
610 620 630 640 650
GWPFKLPKTI LDLVHLEAVF DVMDLYLWLS YRFMDLFPEA AYVRDAQKEL
660 670 680 690 700
DEIIQQGVFQ ITRLLKNTEA SQDGETSNYA IRRITHVKEP RLPSLSRGRL
710 720 730 740 750
TERLLAQGLL TPGMLSELRK EWDAQQLGKS NSQSNENSEP VVNSDDEDNY
760
SGIGRKTRKK RRK
Length:763
Mass (Da):86,625
Last modified:July 7, 2009 - v3
Checksum:iDA7236B10764ADCC
GO

Sequence cautioni

The sequence AAL13756 differs from that shown. Reason: Frameshift at position 241.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAF52149.3.
AY058527 mRNA. Translation: AAL13756.1. Frameshift.
RefSeqiNP_001303458.1. NM_001316529.1.
NP_649452.3. NM_141195.4.
UniGeneiDm.4174.

Genome annotation databases

EnsemblMetazoaiFBtr0273009; FBpp0271517; FBgn0037232.
GeneIDi40543.
KEGGidme:Dmel_CG9791.
UCSCiCG9791-RC. d. melanogaster.

Similar proteinsi

Entry informationi

Entry nameiSUV3_DROME
AccessioniPrimary (citable) accession number: Q9VN03
Secondary accession number(s): Q95TU1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: July 7, 2009
Last modified: August 30, 2017
This is version 124 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families