Reviewed, UniProtKB/Swiss-Prot Q9VMX1 (KBP_DROME)

Names and origin

Protein names

Recommended name:
    Protein KBP homolog

Gene names

ORF Names:

CG14043

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	600 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	May regulate mitochondrial transport By similarity.
Subcellular location	Mitochondrion By similarity.
Sequence similarities	Belongs to the KIF1-binding protein family.
Sequence caution	The sequence AAR30198.1 differs from that shown. Reason: Frameshift at position 163.

Ontologies

Keywords
Cellular component	Mitochondrion
Domain	Coiled coil
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mitochondrial transport Inferred from sequence or structural similarity. Source: UniProtKB
Cellular component	mitochondrion Inferred from sequence or structural similarity. Source: UniProtKB
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
ncd	P20480	1	EBI-155043,EBI-84482

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 600	600	Protein KBP homolog		PRO_0000334520
Regions
	Coiled coil	384 – 434	51	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9VMX1-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: B9644F90BF6CC2BC	FASTA	600	69,685
	10 20 30 40 50 60 MVIPKEILSD FKELYEKANR LVEEESRNDP PTDPFRSHYK ARDVLIVLKK QLDDQLVSVQ 70 80 90 100 110 120 ASEEDGGQDD RCYHSLLAFV CRDLGRIYIY TEEQAEGEKM LNRCLELVTP FKECPEGIIP 130 140 150 160 170 180 FIGAINELSI VLASKEEYNK GLEILLEAEK IYEDFKASGL KPLAIQDVFN PPEEGQQSHE 190 200 210 220 230 240 AGPKELESLY TLVSFYMAQM YGHLGEPEKS AKCCHRTLHR QLESKTYDPI DFALNTATLS 250 260 270 280 290 300 QFYIGEKRFE EARHHLAAAT LIMAEYEVHM LEPEMSEKQR QDVSETFKHR YADVARCWAK 310 320 330 340 350 360 YGLYLMNTSK LRLMRDEDDE DAKNLEIVLR NMRLVEAEQS RFPGLDLTAC ENRISCEYCL 370 380 390 400 410 420 TFDDAKLVFH FVNEWLDIAK DYYKAENEAT EYSKIMQDYA EAYEHIAFFE ENPENQAKMQ 430 440 450 460 470 480 KRRAKYLEDL LDLLDPIFYM KICRECWYGA GTAHAAVMDV RLDIIRATST PAPEDIKKVN 490 500 510 520 530 540 QSCMKAIKHF ESYVKSYLVK PPSEEWRPNM DVEEQRHMLY AHFHIGRIYY KLISGHPLQQ 550 560 570 580 590 600 LEHLTSCHTY YQRFDAGCQL HKEAAETLQG EIGVVREMLQ LLPLKINTIK ARLNKAGLTA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: GENOME REANNOTATION.
[3]	"A Drosophila full-length cDNA resource." Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A., Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M., Celniker S.E. Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002) [PubMed: 12537569] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: Berkeley. Tissue: Embryo.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014134 Genomic DNA. Translation: AAF52187.1. BT011038 mRNA. Translation: AAR30198.1. Frameshift.
RefSeq	NP_608886.1.
UniGene	Dm.6812
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9VMX1. 1 interaction.
Proteomic databases
PRIDE	Q9VMX1.
Genome annotation databases
Ensembl	FBgn0031659. Drosophila melanogaster. [Contig view]
GeneID	33714.
KEGG	dme:Dmel_CG14043.
NMPDR	fig|7227.3.peg.798.
Organism-specific databases
FlyBase	FBgn0031659. CG14043.
Phylogenomic databases
HOGENOM	Q9VMX1.
OMA	Q9VMX1. SMQDNIG.
Gene expression databases
ArrayExpress	Q9VMX1.
Family and domain databases
ProtoNet	Search...
Other Resources
NextBio	784920.

Entry information

Entry name

KBP_DROME

Accession

Primary (citable) accession number: Q9VMX1
Secondary accession number(s): Q6NP90

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	May 1, 2000
Last modified:	July 7, 2009
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Drosophila annotation project