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Q9VMR4 (Q9VMR4_DROME) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 129. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names

No mechanoreceptor potential C, isoform A EMBL AAF52248.3
Gene names
Name:nompC EMBL AAF52248.3 FlyBase FBgn0016920
ORF Names:CG11020 FlyBase FBgn0016920, Dmel_CG11020 EMBL AAF52248.3
OrganismDrosophila melanogaster (Fruit fly) [Reference proteome] EMBL AAF52248.3
Taxonomic identifier7227 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Protein attributes

Sequence length1619 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 29 ANK repeats. RuleBase RU003321

Ontologies

Keywords
   Biological processIon transport
Transport
   Cellular componentMembrane
   DomainANK repeat SAAS SAAS005821 RuleBase RU003321
Repeat RuleBase RU003536
Transmembrane RuleBase RU003378
   Molecular functionIon channel RuleBase RU003378
Receptor EMBL AAF52248.3
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcalcium ion transmembrane transport

Inferred from sequence or structural similarity PubMed 10798390. Source: GOC

calcium ion transport

Inferred from sequence or structural similarity PubMed 10798390. Source: FlyBase

detection of mechanical stimulus involved in sensory perception

Traceable author statement PubMed 14624845. Source: FlyBase

ion transmembrane transport

Inferred from sequence or structural similarity PubMed 10744543. Source: GOC

locomotion

Inferred from mutant phenotype PubMed 20696376. Source: FlyBase

mechanosensory behavior

Inferred from mutant phenotype PubMed 10744543. Source: FlyBase

response to auditory stimulus

Inferred from direct assay PubMed 23898199. Source: FlyBase

sensory perception of mechanical stimulus

Inferred from mutant phenotype PubMed 23590241. Source: FlyBase

sensory perception of sound

Inferred from mutant phenotype PubMed 10934246PubMed 12642657PubMed 16819519PubMed 19666538. Source: FlyBase

sensory perception of touch

Inferred from mutant phenotype PubMed 23103192. Source: FlyBase

startle response

Inferred from mutant phenotype PubMed 23898199. Source: FlyBase

   Cellular_componentcilium

Inferred from direct assay PubMed 20543979PubMed 20696376PubMed 21069788PubMed 23222543. Source: FlyBase

dendrite

Inferred from direct assay PubMed 23222543. Source: FlyBase

integral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

neuronal cell body

Inferred from direct assay PubMed 23222543. Source: FlyBase

   Molecular_functionankyrin binding

Non-traceable author statement PubMed 12647029. Source: FlyBase

calcium channel activity

Inferred from sequence or structural similarity PubMed 10798390. Source: FlyBase

cytoskeletal protein binding

Inferred from sequence or structural similarity PubMed 10908588. Source: FlyBase

ion channel activity

Inferred from sequence or structural similarity PubMed 10744543. Source: FlyBase

mechanically-gated ion channel activity

Non-traceable author statement PubMed 12765692. Source: FlyBase

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q9VMR4 [UniParc].

Last modified October 1, 2002. Version 3.
Checksum: B4FE239ABB1D1138

FASTA1,619176,844
        10         20         30         40         50         60 
MSQPRGGRGG GRGGGVGRKT PSSLTGPPDE SATPSERATP ASKADSDPKD DSSSNGDKKD 

        70         80         90        100        110        120 
MDLFPAPKPP SAGASIRDTA NKVLGLAMKS EWTPIEAELK KLEKYVANVG EDGNHIPLAG 

       130        140        150        160        170        180 
VHDMNTGMTP LMYATKDNKT AIMDRMIELG ADVGARNNDN YNVLHIAAMY SREDVVKLLL 

       190        200        210        220        230        240 
TKRGVDPFST GGSRSQTAVH LVSSRQTGTA TNILRALLAA AGKDIRLKAD GRGKIPLLLA 

       250        260        270        280        290        300 
VESGNQSMCR ELLAAQTAEQ LKATTANGDT ALHLAARRRD VDMVRILVDY GTNVDTQNGE 

       310        320        330        340        350        360 
GQTPLHIAAA EGDEALLKYF YGVRASASIA DNQDRTPMHL AAENGHAHVI EILADKFKAS 

       370        380        390        400        410        420 
IFERTKDGST LMHIASLNGH AECATMLFKK GVYLHMPNKD GARSIHTAAA YGHTGIINTL 

       430        440        450        460        470        480 
LQKGEKVDVT TNDNYTALHI AVESAKPAVV ETLLGFGADV HVRGGKLRET PLHIAARVKD 

       490        500        510        520        530        540 
GDRCALMLLK SGASPNLTTD DCLTPVHVAA RHGNLATLMQ LLEDEGDPLY KSNTGETPLH 

       550        560        570        580        590        600 
MACRACHPDI VRHLIETVKE KHGPDKATTY INSVNEDGAT ALHYTCQITK EEVKIPESDK 

       610        620        630        640        650        660 
QIVRMLLENG ADVTLQTKTA LETAFHYCAV AGNNDVLMEM ISHMNPTDIQ KAMNRQSSVG 

       670        680        690        700        710        720 
WTPLLIACHR GHMELVNNLL ANHARVDVFD TEGRSALHLA AERGYLHVCD ALLTNKAFIN 

       730        740        750        760        770        780 
SKSRVGRTAL HLAAMNGFTH LVKFLIKDHN AVIDILTLRK QTPLHLAAAS GQMEVCQLLL 

       790        800        810        820        830        840 
ELGANIDATD DLGQKPIHVA AQNNYSEVAK LFLQQHPSLV NATSKDGNTC AHIAAMQGSV 

       850        860        870        880        890        900 
KVIEELMKFD RSGVISARNK LTDATPLQLA AEGGHADVVK ALVRAGASCT EENKAGFTAV 

       910        920        930        940        950        960 
HLAAQNGHGQ VLDVLKSTNS LRINSKKLGL TPLHVAAYYG QADTVRELLT SVPATVKSET 

       970        980        990       1000       1010       1020 
PTGQSLFGDL GTESGMTPLH LAAFSGNENV VRLLLNSAGV QVDAATIENG YNPLHLACFG 

      1030       1040       1050       1060       1070       1080 
GHMSVVGLLL SRSAELLQSQ DRNGRTGLHI AAMHGHIQMV EILLGQGAEI NATDRNGWTP 

      1090       1100       1110       1120       1130       1140 
LHCAAKAGHL EVVKLLCEAG ASPKSETNYG CAAIWFAASE GHNEVLRYLM NKEHDTYGLM 

      1150       1160       1170       1180       1190       1200 
EDKRFVYNLM VVSKNHNNKP IQEFVLVSPA PVDTAAKLSN IYIVLSTKEK ERAKDLVAAG 

      1210       1220       1230       1240       1250       1260 
KQCEAMATEL LALAAGSDSA GKILQATDKR NVEFLDVLIE NEQKEVIAHT VVQRYLQELW 

      1270       1280       1290       1300       1310       1320 
HGSLTWASWK ILLLLVAFIV CPPVWIGFTF PMGHKFNKVP IIKFMSYLTS HIYLMIHLSI 

      1330       1340       1350       1360       1370       1380 
VGITPIYPVL RLSLVPYWYE VGLLIWLSGL LLFELTNPSD KSGLGSIKVL VLLLGMAGVG 

      1390       1400       1410       1420       1430       1440 
VHVSAFLFVS KEYWPTLVYC RNQCFALAFL LACVQILDFL SFHHLFGPWA IIIGDLLKDL 

      1450       1460       1470       1480       1490       1500 
ARFLAVLAIF VFGFSMHIVA LNQSFANFSP EDLRSFEKKN RNRGYFSDVR MHPINSFELL 

      1510       1520       1530       1540       1550       1560 
FFAVFGQTTT EQTQVDKIKN VATPTQPYWV EYLFKIVFGI YMLVSVVVLI NLLIAMMSDT 

      1570       1580       1590       1600       1610 
YQRIQVVLLN ALLSNSTLFI NSYFNHKYIN FILHCVLIIL YFSIRSKFTY EDDLYFLDI 

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[2]"A Drosophila mechanosensory transduction channel."
Walker R.G., Willingham A.T., Zuker C.S.
Science 0:0-0(2000)
Cited for: NUCLEOTIDE SEQUENCE.
[3]"Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence."
Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., Pacleb J.M., Park S. expand/collapse author list , Pfeiffer B.D., Richards S., Sodergren E.J., Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.
Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[4]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: Berkeley.
[5]"The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective."
Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M., Celniker S.E.
Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[6]"Heterochromatic sequences in a Drosophila whole-genome shotgun assembly."
Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., Karpen G.H.
Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[7]"Combined evidence annotation of transposable elements in genome sequences."
Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., Ashburner M., Anxolabehere D.
PLoS Comput. Biol. 1:166-175(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[8]Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S., Svirskas R., Rubin G.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[9]"Drosophila melanogaster release 4 sequence."
Berkeley Drosophila Genome Project
Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., Yu C., Rubin G.
Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[10]"The Release 5.1 annotation of Drosophila melanogaster heterochromatin."
Smith C.D., Shu S., Mungall C.J., Karpen G.H.
Science 316:1586-1591(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[11]"Sequence finishing and mapping of Drosophila melanogaster heterochromatin."
Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., Dimitri P., Karpen G.H., Celniker S.E.
Science 316:1625-1628(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[12]FlyBase
Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014134 Genomic DNA. Translation: AAF52248.3.
AF242296 mRNA. Translation: AAF59842.1.
RefSeqNP_523483.1. NM_078759.3.
UniGeneDm.3306.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein family/group databases

TCDB1.A.4.7.2. the transient receptor potential ca(2+) channel (trp-cc) family.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0079074; FBpp0078709; FBgn0016920.
GeneID33768.
KEGGdme:Dmel_CG11020.
UCSCCG11020-RA. d. melanogaster.

Organism-specific databases

CTD33768.
FlyBaseFBgn0016920. nompC.

Phylogenomic databases

GeneTreeENSGT00740000115059.
InParanoidQ9VMR4.

Family and domain databases

Gene3D1.25.40.20. 5 hits.
InterProIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR005821. Ion_trans_dom.
[Graphical view]
PfamPF00023. Ank. 2 hits.
PF12796. Ank_2. 8 hits.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSPR01415. ANKYRIN.
SMARTSM00248. ANK. 29 hits.
[Graphical view]
SUPFAMSSF48403. SSF48403. 4 hits.
PROSITEPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 20 hits.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi33768.
NextBio785156.

Entry information

Entry nameQ9VMR4_DROME
AccessionPrimary (citable) accession number: Q9VMR4
Secondary accession number(s): Q9NGR8
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: October 1, 2002
Last modified: June 11, 2014
This is version 129 of the entry and version 3 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)