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Q9VMR4

- Q9VMR4_DROME

UniProt

Q9VMR4 - Q9VMR4_DROME

Protein
Submitted name:

Mechanosensory transduction channel NOMPC

Gene

nompC

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 130 (01 Oct 2014)
      Sequence version 3 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ankyrin binding Source: FlyBase
    2. calcium channel activity Source: FlyBase
    3. cytoskeletal protein binding Source: FlyBase
    4. ion channel activity Source: FlyBase
    5. mechanically-gated ion channel activity Source: FlyBase

    GO - Biological processi

    1. calcium ion transmembrane transport Source: GOC
    2. calcium ion transport Source: FlyBase
    3. detection of mechanical stimulus involved in sensory perception Source: FlyBase
    4. ion transmembrane transport Source: GOC
    5. locomotion Source: FlyBase
    6. mechanosensory behavior Source: FlyBase
    7. response to auditory stimulus Source: FlyBase
    8. sensory perception of mechanical stimulus Source: FlyBase
    9. sensory perception of sound Source: FlyBase
    10. sensory perception of touch Source: FlyBase
    11. startle response Source: FlyBase

    Keywords - Molecular functioni

    Ion channelUniRule annotation, ReceptorImported

    Keywords - Biological processi

    Ion transport, Transport

    Protein family/group databases

    TCDBi1.A.4.7.2. the transient receptor potential ca(2+) channel (trp-cc) family.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Mechanosensory transduction channel NOMPCImported
    Submitted name:
    No mechanoreceptor potential C, isoform AImported
    Gene namesi
    Name:nompCImported
    ORF Names:CG11020Imported, Dmel_CG11020Imported
    OrganismiDrosophila melanogaster (Fruit fly)Imported
    Taxonomic identifieri7227 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000000803: Chromosome 2L

    Organism-specific databases

    FlyBaseiFBgn0016920. nompC.

    Subcellular locationi

    GO - Cellular componenti

    1. cilium Source: FlyBase
    2. dendrite Source: FlyBase
    3. integral component of membrane Source: UniProtKB-KW
    4. neuronal cell body Source: FlyBase

    Keywords - Cellular componenti

    Membrane

    Family & Domainsi

    Sequence similaritiesi

    Contains 29 ANK repeats.UniRule annotation

    Keywords - Domaini

    ANK repeatUniRule annotationSAAS annotation, RepeatUniRule annotation, TransmembraneUniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00740000115059.
    InParanoidiQ9VMR4.

    Family and domain databases

    Gene3Di1.25.40.20. 5 hits.
    InterProiIPR002110. Ankyrin_rpt.
    IPR020683. Ankyrin_rpt-contain_dom.
    IPR005821. Ion_trans_dom.
    [Graphical view]
    PfamiPF00023. Ank. 2 hits.
    PF12796. Ank_2. 8 hits.
    PF00520. Ion_trans. 1 hit.
    [Graphical view]
    PRINTSiPR01415. ANKYRIN.
    SMARTiSM00248. ANK. 29 hits.
    [Graphical view]
    SUPFAMiSSF48403. SSF48403. 4 hits.
    PROSITEiPS50297. ANK_REP_REGION. 1 hit.
    PS50088. ANK_REPEAT. 20 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9VMR4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSQPRGGRGG GRGGGVGRKT PSSLTGPPDE SATPSERATP ASKADSDPKD     50
    DSSSNGDKKD MDLFPAPKPP SAGASIRDTA NKVLGLAMKS EWTPIEAELK 100
    KLEKYVANVG EDGNHIPLAG VHDMNTGMTP LMYATKDNKT AIMDRMIELG 150
    ADVGARNNDN YNVLHIAAMY SREDVVKLLL TKRGVDPFST GGSRSQTAVH 200
    LVSSRQTGTA TNILRALLAA AGKDIRLKAD GRGKIPLLLA VESGNQSMCR 250
    ELLAAQTAEQ LKATTANGDT ALHLAARRRD VDMVRILVDY GTNVDTQNGE 300
    GQTPLHIAAA EGDEALLKYF YGVRASASIA DNQDRTPMHL AAENGHAHVI 350
    EILADKFKAS IFERTKDGST LMHIASLNGH AECATMLFKK GVYLHMPNKD 400
    GARSIHTAAA YGHTGIINTL LQKGEKVDVT TNDNYTALHI AVESAKPAVV 450
    ETLLGFGADV HVRGGKLRET PLHIAARVKD GDRCALMLLK SGASPNLTTD 500
    DCLTPVHVAA RHGNLATLMQ LLEDEGDPLY KSNTGETPLH MACRACHPDI 550
    VRHLIETVKE KHGPDKATTY INSVNEDGAT ALHYTCQITK EEVKIPESDK 600
    QIVRMLLENG ADVTLQTKTA LETAFHYCAV AGNNDVLMEM ISHMNPTDIQ 650
    KAMNRQSSVG WTPLLIACHR GHMELVNNLL ANHARVDVFD TEGRSALHLA 700
    AERGYLHVCD ALLTNKAFIN SKSRVGRTAL HLAAMNGFTH LVKFLIKDHN 750
    AVIDILTLRK QTPLHLAAAS GQMEVCQLLL ELGANIDATD DLGQKPIHVA 800
    AQNNYSEVAK LFLQQHPSLV NATSKDGNTC AHIAAMQGSV KVIEELMKFD 850
    RSGVISARNK LTDATPLQLA AEGGHADVVK ALVRAGASCT EENKAGFTAV 900
    HLAAQNGHGQ VLDVLKSTNS LRINSKKLGL TPLHVAAYYG QADTVRELLT 950
    SVPATVKSET PTGQSLFGDL GTESGMTPLH LAAFSGNENV VRLLLNSAGV 1000
    QVDAATIENG YNPLHLACFG GHMSVVGLLL SRSAELLQSQ DRNGRTGLHI 1050
    AAMHGHIQMV EILLGQGAEI NATDRNGWTP LHCAAKAGHL EVVKLLCEAG 1100
    ASPKSETNYG CAAIWFAASE GHNEVLRYLM NKEHDTYGLM EDKRFVYNLM 1150
    VVSKNHNNKP IQEFVLVSPA PVDTAAKLSN IYIVLSTKEK ERAKDLVAAG 1200
    KQCEAMATEL LALAAGSDSA GKILQATDKR NVEFLDVLIE NEQKEVIAHT 1250
    VVQRYLQELW HGSLTWASWK ILLLLVAFIV CPPVWIGFTF PMGHKFNKVP 1300
    IIKFMSYLTS HIYLMIHLSI VGITPIYPVL RLSLVPYWYE VGLLIWLSGL 1350
    LLFELTNPSD KSGLGSIKVL VLLLGMAGVG VHVSAFLFVS KEYWPTLVYC 1400
    RNQCFALAFL LACVQILDFL SFHHLFGPWA IIIGDLLKDL ARFLAVLAIF 1450
    VFGFSMHIVA LNQSFANFSP EDLRSFEKKN RNRGYFSDVR MHPINSFELL 1500
    FFAVFGQTTT EQTQVDKIKN VATPTQPYWV EYLFKIVFGI YMLVSVVVLI 1550
    NLLIAMMSDT YQRIQVVLLN ALLSNSTLFI NSYFNHKYIN FILHCVLIIL 1600
    YFSIRSKFTY EDDLYFLDI 1619
    Length:1,619
    Mass (Da):176,844
    Last modified:October 1, 2002 - v3
    Checksum:iB4FE239ABB1D1138
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014134 Genomic DNA. Translation: AAF52248.3.
    AF242296 mRNA. Translation: AAF59842.1.
    RefSeqiNP_523483.1. NM_078759.3.
    UniGeneiDm.3306.

    Genome annotation databases

    EnsemblMetazoaiFBtr0079074; FBpp0078709; FBgn0016920.
    GeneIDi33768.
    KEGGidme:Dmel_CG11020.
    UCSCiCG11020-RA. d. melanogaster.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014134 Genomic DNA. Translation: AAF52248.3 .
    AF242296 mRNA. Translation: AAF59842.1 .
    RefSeqi NP_523483.1. NM_078759.3.
    UniGenei Dm.3306.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    TCDBi 1.A.4.7.2. the transient receptor potential ca(2+) channel (trp-cc) family.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0079074 ; FBpp0078709 ; FBgn0016920 .
    GeneIDi 33768.
    KEGGi dme:Dmel_CG11020.
    UCSCi CG11020-RA. d. melanogaster.

    Organism-specific databases

    CTDi 33768.
    FlyBasei FBgn0016920. nompC.

    Phylogenomic databases

    GeneTreei ENSGT00740000115059.
    InParanoidi Q9VMR4.

    Miscellaneous databases

    GenomeRNAii 33768.
    NextBioi 785156.

    Family and domain databases

    Gene3Di 1.25.40.20. 5 hits.
    InterProi IPR002110. Ankyrin_rpt.
    IPR020683. Ankyrin_rpt-contain_dom.
    IPR005821. Ion_trans_dom.
    [Graphical view ]
    Pfami PF00023. Ank. 2 hits.
    PF12796. Ank_2. 8 hits.
    PF00520. Ion_trans. 1 hit.
    [Graphical view ]
    PRINTSi PR01415. ANKYRIN.
    SMARTi SM00248. ANK. 29 hits.
    [Graphical view ]
    SUPFAMi SSF48403. SSF48403. 4 hits.
    PROSITEi PS50297. ANK_REP_REGION. 1 hit.
    PS50088. ANK_REPEAT. 20 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Drosophila melanogaster."
      Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
      , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
      Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BerkeleyImported.
    2. "A Drosophila mechanosensory transduction channel."
      Walker R.G., Willingham A.T., Zuker C.S.
      Science 0:0-0(2000)
      Cited for: NUCLEOTIDE SEQUENCE.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BerkeleyImported.
    4. Cited for: GENOME REANNOTATION.
      Strain: BerkeleyImported.
    5. "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective."
      Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M., Celniker S.E.
      Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BerkeleyImported.
    6. "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly."
      Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., Karpen G.H.
      Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BerkeleyImported.
    7. "Combined evidence annotation of transposable elements in genome sequences."
      Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., Ashburner M., Anxolabehere D.
      PLoS Comput. Biol. 1:166-175(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BerkeleyImported.
    8. Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S., Svirskas R., Rubin G.
      Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    9. "Drosophila melanogaster release 4 sequence."
      Berkeley Drosophila Genome Project
      Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., Yu C., Rubin G.
      Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    10. "The Release 5.1 annotation of Drosophila melanogaster heterochromatin."
      Smith C.D., Shu S., Mungall C.J., Karpen G.H.
      Science 316:1586-1591(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BerkeleyImported.
    11. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BerkeleyImported.
    12. FlyBase
      Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ9VMR4_DROME
    AccessioniPrimary (citable) accession number: Q9VMR4
    Secondary accession number(s): Q9NGR8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 2000
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 130 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3