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Protein
Submitted name:

No mechanoreceptor potential C, isoform H

Gene

nompC

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • ankyrin binding Source: FlyBase
  • calcium channel activity Source: FlyBase
  • cation channel activity Source: FlyBase
  • cytoskeletal protein binding Source: FlyBase
  • ion channel activity Source: FlyBase
  • mechanically-gated ion channel activity Source: FlyBase

GO - Biological processi

  • calcium ion transport Source: FlyBase
  • cation transport Source: FlyBase
  • cellular response to mechanical stimulus Source: FlyBase
  • detection of mechanical stimulus involved in sensory perception Source: FlyBase
  • detection of mechanical stimulus involved in sensory perception of touch Source: FlyBase
  • locomotion Source: FlyBase
  • mechanosensory behavior Source: FlyBase
  • response to auditory stimulus Source: FlyBase
  • sensory perception of mechanical stimulus Source: FlyBase
  • sensory perception of sound Source: FlyBase
  • sensory perception of touch Source: FlyBase
  • startle response Source: FlyBase
Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotationSAAS annotation, ReceptorImported

Keywords - Biological processi

Ion transport, Transport

Protein family/group databases

TCDBi1.A.4.7.2. the transient receptor potential ca(2+) channel (trp-cc) family.

Names & Taxonomyi

Protein namesi
Submitted name:
No mechanoreceptor potential C, isoform HImported
Gene namesi
Name:nompCImported
ORF Names:CG11020Imported, Dmel_CG11020Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0016920. nompC.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1271 – 129121HelicalSequence analysisAdd
BLAST
Transmembranei1312 – 133019HelicalSequence analysisAdd
BLAST
Transmembranei1336 – 135520HelicalSequence analysisAdd
BLAST
Transmembranei1367 – 138923HelicalSequence analysisAdd
BLAST
Transmembranei1409 – 143325HelicalSequence analysisAdd
BLAST
Transmembranei1440 – 146021HelicalSequence analysisAdd
BLAST
Transmembranei1561 – 158323HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • cation channel complex Source: FlyBase
  • cilium Source: FlyBase
  • dendrite Source: FlyBase
  • neuronal cell body Source: FlyBase
  • spanning component of plasma membrane Source: FlyBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

ExpressionAtlasiQ9VMR4. differential.

Interactioni

GO - Molecular functioni

  • ankyrin binding Source: FlyBase
  • cytoskeletal protein binding Source: FlyBase

Protein-protein interaction databases

IntActiQ9VMR4. 5 interactions.
STRINGi7227.FBpp0293383.

Family & Domainsi

Sequence similaritiesi

Belongs to the transient receptor (TC 1.A.4) family. [View classification]SAAS annotation
Contains 20 ANK repeats.UniRule annotation

Keywords - Domaini

ANK repeatUniRule annotationSAAS annotation, RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3609. Eukaryota.
KOG4177. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00840000129677.

Family and domain databases

Gene3Di1.25.40.20. 5 hits.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR005821. Ion_trans_dom.
IPR002153. TRPC_channel.
[Graphical view]
PfamiPF00023. Ank. 1 hit.
PF12796. Ank_2. 7 hits.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
PR01097. TRNSRECEPTRP.
SMARTiSM00248. ANK. 29 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 4 hits.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 20 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9VMR4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQPRGGRGG GRGGGVGRKT PSSLTGPPDE SATPSERATP ASKADSDPKD
60 70 80 90 100
DSSSNGDKKD MDLFPAPKPP SAGASIRDTA NKVLGLAMKS EWTPIEAELK
110 120 130 140 150
KLEKYVANVG EDGNHIPLAG VHDMNTGMTP LMYATKDNKT AIMDRMIELG
160 170 180 190 200
ADVGARNNDN YNVLHIAAMY SREDVVKLLL TKRGVDPFST GGSRSQTAVH
210 220 230 240 250
LVSSRQTGTA TNILRALLAA AGKDIRLKAD GRGKIPLLLA VESGNQSMCR
260 270 280 290 300
ELLAAQTAEQ LKATTANGDT ALHLAARRRD VDMVRILVDY GTNVDTQNGE
310 320 330 340 350
GQTPLHIAAA EGDEALLKYF YGVRASASIA DNQDRTPMHL AAENGHAHVI
360 370 380 390 400
EILADKFKAS IFERTKDGST LMHIASLNGH AECATMLFKK GVYLHMPNKD
410 420 430 440 450
GARSIHTAAA YGHTGIINTL LQKGEKVDVT TNDNYTALHI AVESAKPAVV
460 470 480 490 500
ETLLGFGADV HVRGGKLRET PLHIAARVKD GDRCALMLLK SGASPNLTTD
510 520 530 540 550
DCLTPVHVAA RHGNLATLMQ LLEDEGDPLY KSNTGETPLH MACRACHPDI
560 570 580 590 600
VRHLIETVKE KHGPDKATTY INSVNEDGAT ALHYTCQITK EEVKIPESDK
610 620 630 640 650
QIVRMLLENG ADVTLQTKTA LETAFHYCAV AGNNDVLMEM ISHMNPTDIQ
660 670 680 690 700
KAMNRQSSVG WTPLLIACHR GHMELVNNLL ANHARVDVFD TEGRSALHLA
710 720 730 740 750
AERGYLHVCD ALLTNKAFIN SKSRVGRTAL HLAAMNGFTH LVKFLIKDHN
760 770 780 790 800
AVIDILTLRK QTPLHLAAAS GQMEVCQLLL ELGANIDATD DLGQKPIHVA
810 820 830 840 850
AQNNYSEVAK LFLQQHPSLV NATSKDGNTC AHIAAMQGSV KVIEELMKFD
860 870 880 890 900
RSGVISARNK LTDATPLQLA AEGGHADVVK ALVRAGASCT EENKAGFTAV
910 920 930 940 950
HLAAQNGHGQ VLDVLKSTNS LRINSKKLGL TPLHVAAYYG QADTVRELLT
960 970 980 990 1000
SVPATVKSET PTGQSLFGDL GTESGMTPLH LAAFSGNENV VRLLLNSAGV
1010 1020 1030 1040 1050
QVDAATIENG YNPLHLACFG GHMSVVGLLL SRSAELLQSQ DRNGRTGLHI
1060 1070 1080 1090 1100
AAMHGHIQMV EILLGQGAEI NATDRNGWTP LHCAAKAGHL EVVKLLCEAG
1110 1120 1130 1140 1150
ASPKSETNYG CAAIWFAASE GHNEVLRYLM NKEHDTYGLM EDKRFVYNLM
1160 1170 1180 1190 1200
VVSKNHNNKP IQEFVLVSPA PVDTAAKLSN IYIVLSTKEK ERAKDLVAAG
1210 1220 1230 1240 1250
KQCEAMATEL LALAAGSDSA GKILQATDKR NVEFLDVLIE NEQKEVIAHT
1260 1270 1280 1290 1300
VVQRYLQELW HGSLTWASWK ILLLLVAFIV CPPVWIGFTF PMGHKFNKVP
1310 1320 1330 1340 1350
IIKFMSYLTS HIYLMIHLSI VGITPIYPVL RLSLVPYWYE VGLLIWLSGL
1360 1370 1380 1390 1400
LLFELTNPSD KSGLGSIKVL VLLLGMAGVG VHVSAFLFVS KEYWPTLVYC
1410 1420 1430 1440 1450
RNQCFALAFL LACVQILDFL SFHHLFGPWA IIIGDLLKDL ARFLAVLAIF
1460 1470 1480 1490 1500
VFGFSMHIVA LNQSFANFSP EDLRSFEKKN RNRGYFSDDD MPTPRPPPVE
1510 1520 1530 1540 1550
NYVDSRFSEF RRKHKDDLRM HPINSFELLF FAVFGQTTTE QTQVDKIKNV
1560 1570 1580 1590 1600
ATPTQPYWVE YLFKIVFGIY MLVSVVVLIN LLIAMMSDTY QRIQAQSDIE
1610 1620 1630 1640 1650
WKFGLSKLIR NMHRTTTAPS PLNLVTTWFM WIVEKVKARM KKKKRPSLVQ
1660 1670 1680 1690 1700
MMGIRQASPR TKAGAKWLSK IKKDSVALSQ VHLSPLGSQA SFSQANQNRI
1710 1720 1730 1740 1750
ENVADWEAIA KKYRALVGDE EGGSLKDSDA ESGSQEGSGG QQPPAQVGRR
1760
AIKATLADTT K
Length:1,761
Mass (Da):192,252
Last modified:February 17, 2016 - v4
Checksum:i0F84F210EB56C740
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA. Translation: AAF52248.4.
RefSeqiNP_523483.2. NM_078759.4.
UniGeneiDm.3306.

Genome annotation databases

EnsemblMetazoaiFBtr0079074; FBpp0078709; FBgn0016920.
GeneIDi33768.
UCSCiCG11020-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA. Translation: AAF52248.4.
RefSeqiNP_523483.2. NM_078759.4.
UniGeneiDm.3306.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9VMR4. 5 interactions.
STRINGi7227.FBpp0293383.

Protein family/group databases

TCDBi1.A.4.7.2. the transient receptor potential ca(2+) channel (trp-cc) family.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0079074; FBpp0078709; FBgn0016920.
GeneIDi33768.
UCSCiCG11020-RA. d. melanogaster.

Organism-specific databases

CTDi33768.
FlyBaseiFBgn0016920. nompC.

Phylogenomic databases

eggNOGiKOG3609. Eukaryota.
KOG4177. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00840000129677.

Miscellaneous databases

GenomeRNAii33768.

Gene expression databases

ExpressionAtlasiQ9VMR4. differential.

Family and domain databases

Gene3Di1.25.40.20. 5 hits.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR005821. Ion_trans_dom.
IPR002153. TRPC_channel.
[Graphical view]
PfamiPF00023. Ank. 1 hit.
PF12796. Ank_2. 7 hits.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
PR01097. TRNSRECEPTRP.
SMARTiSM00248. ANK. 29 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 4 hits.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 20 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Drosophila melanogaster."
    Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
    , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
    Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  3. Cited for: GENOME REANNOTATION.
    Strain: BerkeleyImported.
  4. "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective."
    Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M., Celniker S.E.
    Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  5. "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly."
    Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., Karpen G.H.
    Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  6. "Combined evidence annotation of transposable elements in genome sequences."
    Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., Ashburner M., Anxolabehere D.
    PLoS Comput. Biol. 1:166-175(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  7. "The Release 5.1 annotation of Drosophila melanogaster heterochromatin."
    Smith C.D., Shu S., Mungall C.J., Karpen G.H.
    Science 316:1586-1591(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  8. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.

Entry informationi

Entry nameiQ9VMR4_DROME
AccessioniPrimary (citable) accession number: Q9VMR4
Secondary accession number(s): Q9NGR8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: February 17, 2016
Last modified: July 6, 2016
This is version 149 of the entry and version 4 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.