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Q9VMR4

- Q9VMR4_DROME

UniProt

Q9VMR4 - Q9VMR4_DROME

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Protein
Submitted name:

Mechanosensory transduction channel NOMPC

Gene
nompC, CG11020, Dmel_CG11020
Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ankyrin binding Source: FlyBase
  2. calcium channel activity Source: FlyBase
  3. cytoskeletal protein binding Source: FlyBase
  4. ion channel activity Source: FlyBase
  5. mechanically-gated ion channel activity Source: FlyBase

GO - Biological processi

  1. calcium ion transmembrane transport Source: GOC
  2. calcium ion transport Source: FlyBase
  3. detection of mechanical stimulus involved in sensory perception Source: FlyBase
  4. ion transmembrane transport Source: GOC
  5. locomotion Source: FlyBase
  6. mechanosensory behavior Source: FlyBase
  7. response to auditory stimulus Source: FlyBase
  8. sensory perception of mechanical stimulus Source: FlyBase
  9. sensory perception of sound Source: FlyBase
  10. sensory perception of touch Source: FlyBase
  11. startle response Source: FlyBase
Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotation, ReceptorImported

Keywords - Biological processi

Ion transport, Transport

Protein family/group databases

TCDBi1.A.4.7.2. the transient receptor potential ca(2+) channel (trp-cc) family.

Names & Taxonomyi

Protein namesi
Submitted name:
Mechanosensory transduction channel NOMPCImported
Submitted name:
No mechanoreceptor potential C, isoform AImported
Gene namesi
Name:nompCImported
ORF Names:CG11020Imported, Dmel_CG11020Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000000803: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0016920. nompC.

Subcellular locationi

GO - Cellular componenti

  1. cilium Source: FlyBase
  2. dendrite Source: FlyBase
  3. integral component of membrane Source: UniProtKB-KW
  4. neuronal cell body Source: FlyBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Family & Domainsi

Sequence similaritiesi

Contains 29 ANK repeats.UniRule annotation

Keywords - Domaini

ANK repeatUniRule annotationSAAS annotations, RepeatUniRule annotation, TransmembraneUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00740000115059.
InParanoidiQ9VMR4.

Family and domain databases

Gene3Di1.25.40.20. 5 hits.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR005821. Ion_trans_dom.
[Graphical view]
PfamiPF00023. Ank. 2 hits.
PF12796. Ank_2. 8 hits.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 29 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 4 hits.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 20 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9VMR4-1 [UniParc]FASTAAdd to Basket

« Hide

MSQPRGGRGG GRGGGVGRKT PSSLTGPPDE SATPSERATP ASKADSDPKD     50
DSSSNGDKKD MDLFPAPKPP SAGASIRDTA NKVLGLAMKS EWTPIEAELK 100
KLEKYVANVG EDGNHIPLAG VHDMNTGMTP LMYATKDNKT AIMDRMIELG 150
ADVGARNNDN YNVLHIAAMY SREDVVKLLL TKRGVDPFST GGSRSQTAVH 200
LVSSRQTGTA TNILRALLAA AGKDIRLKAD GRGKIPLLLA VESGNQSMCR 250
ELLAAQTAEQ LKATTANGDT ALHLAARRRD VDMVRILVDY GTNVDTQNGE 300
GQTPLHIAAA EGDEALLKYF YGVRASASIA DNQDRTPMHL AAENGHAHVI 350
EILADKFKAS IFERTKDGST LMHIASLNGH AECATMLFKK GVYLHMPNKD 400
GARSIHTAAA YGHTGIINTL LQKGEKVDVT TNDNYTALHI AVESAKPAVV 450
ETLLGFGADV HVRGGKLRET PLHIAARVKD GDRCALMLLK SGASPNLTTD 500
DCLTPVHVAA RHGNLATLMQ LLEDEGDPLY KSNTGETPLH MACRACHPDI 550
VRHLIETVKE KHGPDKATTY INSVNEDGAT ALHYTCQITK EEVKIPESDK 600
QIVRMLLENG ADVTLQTKTA LETAFHYCAV AGNNDVLMEM ISHMNPTDIQ 650
KAMNRQSSVG WTPLLIACHR GHMELVNNLL ANHARVDVFD TEGRSALHLA 700
AERGYLHVCD ALLTNKAFIN SKSRVGRTAL HLAAMNGFTH LVKFLIKDHN 750
AVIDILTLRK QTPLHLAAAS GQMEVCQLLL ELGANIDATD DLGQKPIHVA 800
AQNNYSEVAK LFLQQHPSLV NATSKDGNTC AHIAAMQGSV KVIEELMKFD 850
RSGVISARNK LTDATPLQLA AEGGHADVVK ALVRAGASCT EENKAGFTAV 900
HLAAQNGHGQ VLDVLKSTNS LRINSKKLGL TPLHVAAYYG QADTVRELLT 950
SVPATVKSET PTGQSLFGDL GTESGMTPLH LAAFSGNENV VRLLLNSAGV 1000
QVDAATIENG YNPLHLACFG GHMSVVGLLL SRSAELLQSQ DRNGRTGLHI 1050
AAMHGHIQMV EILLGQGAEI NATDRNGWTP LHCAAKAGHL EVVKLLCEAG 1100
ASPKSETNYG CAAIWFAASE GHNEVLRYLM NKEHDTYGLM EDKRFVYNLM 1150
VVSKNHNNKP IQEFVLVSPA PVDTAAKLSN IYIVLSTKEK ERAKDLVAAG 1200
KQCEAMATEL LALAAGSDSA GKILQATDKR NVEFLDVLIE NEQKEVIAHT 1250
VVQRYLQELW HGSLTWASWK ILLLLVAFIV CPPVWIGFTF PMGHKFNKVP 1300
IIKFMSYLTS HIYLMIHLSI VGITPIYPVL RLSLVPYWYE VGLLIWLSGL 1350
LLFELTNPSD KSGLGSIKVL VLLLGMAGVG VHVSAFLFVS KEYWPTLVYC 1400
RNQCFALAFL LACVQILDFL SFHHLFGPWA IIIGDLLKDL ARFLAVLAIF 1450
VFGFSMHIVA LNQSFANFSP EDLRSFEKKN RNRGYFSDVR MHPINSFELL 1500
FFAVFGQTTT EQTQVDKIKN VATPTQPYWV EYLFKIVFGI YMLVSVVVLI 1550
NLLIAMMSDT YQRIQVVLLN ALLSNSTLFI NSYFNHKYIN FILHCVLIIL 1600
YFSIRSKFTY EDDLYFLDI 1619
Length:1,619
Mass (Da):176,844
Last modified:October 1, 2002 - v3
Checksum:iB4FE239ABB1D1138
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014134 Genomic DNA. Translation: AAF52248.3.
AF242296 mRNA. Translation: AAF59842.1.
RefSeqiNP_523483.1. NM_078759.3.
UniGeneiDm.3306.

Genome annotation databases

EnsemblMetazoaiFBtr0079074; FBpp0078709; FBgn0016920.
GeneIDi33768.
KEGGidme:Dmel_CG11020.
UCSCiCG11020-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014134 Genomic DNA. Translation: AAF52248.3 .
AF242296 mRNA. Translation: AAF59842.1 .
RefSeqi NP_523483.1. NM_078759.3.
UniGenei Dm.3306.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein family/group databases

TCDBi 1.A.4.7.2. the transient receptor potential ca(2+) channel (trp-cc) family.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0079074 ; FBpp0078709 ; FBgn0016920 .
GeneIDi 33768.
KEGGi dme:Dmel_CG11020.
UCSCi CG11020-RA. d. melanogaster.

Organism-specific databases

CTDi 33768.
FlyBasei FBgn0016920. nompC.

Phylogenomic databases

GeneTreei ENSGT00740000115059.
InParanoidi Q9VMR4.

Miscellaneous databases

GenomeRNAii 33768.
NextBioi 785156.

Family and domain databases

Gene3Di 1.25.40.20. 5 hits.
InterProi IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR005821. Ion_trans_dom.
[Graphical view ]
Pfami PF00023. Ank. 2 hits.
PF12796. Ank_2. 8 hits.
PF00520. Ion_trans. 1 hit.
[Graphical view ]
PRINTSi PR01415. ANKYRIN.
SMARTi SM00248. ANK. 29 hits.
[Graphical view ]
SUPFAMi SSF48403. SSF48403. 4 hits.
PROSITEi PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 20 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Drosophila melanogaster."
    Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
    , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
    Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  2. "A Drosophila mechanosensory transduction channel."
    Walker R.G., Willingham A.T., Zuker C.S.
    Science 0:0-0(2000)
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  4. Cited for: GENOME REANNOTATION.
    Strain: Berkeley.
  5. "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective."
    Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M., Celniker S.E.
    Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  6. "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly."
    Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., Karpen G.H.
    Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  7. "Combined evidence annotation of transposable elements in genome sequences."
    Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., Ashburner M., Anxolabehere D.
    PLoS Comput. Biol. 1:166-175(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  8. Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S., Svirskas R., Rubin G.
    Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  9. "Drosophila melanogaster release 4 sequence."
    Berkeley Drosophila Genome Project
    Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., Yu C., Rubin G.
    Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  10. "The Release 5.1 annotation of Drosophila melanogaster heterochromatin."
    Smith C.D., Shu S., Mungall C.J., Karpen G.H.
    Science 316:1586-1591(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  11. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  12. FlyBase
    Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9VMR4_DROME
AccessioniPrimary (citable) accession number: Q9VMR4
Secondary accession number(s): Q9NGR8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: October 1, 2002
Last modified: June 11, 2014
This is version 129 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi