Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein Wnt

Gene

Wnt6

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Ligand for members of the frizzled family of seven transmembrane receptors.UniRule annotation

GO - Molecular functioni

GO - Biological processi

  • cell fate commitment Source: GO_Central
  • neuron differentiation Source: GO_Central
  • regulation of imaginal disc-derived wing size Source: FlyBase
  • Wnt signaling pathway Source: FlyBase

Keywordsi

Molecular functionDevelopmental proteinUniRule annotationSAAS annotation
Biological processWnt signaling pathwayUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-DME-3238698 WNT ligand biogenesis and trafficking

Names & Taxonomyi

Protein namesi
Recommended name:
Protein WntUniRule annotation
Gene namesi
Name:Wnt6Imported
Synonyms:D-Wnt-6Imported, Dmel\CG4969Imported, DWnt-6Imported, DWnt6Imported, wnt6Imported, Wnt6-RBImported
ORF Names:CG4969Imported, Dmel_CG4969Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0031902 Wnt6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Extracellular matrixSAAS annotation, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501353728623 – 420Protein WntSequence analysisAdd BLAST398

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiFBgn0031902

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7227.FBpp0292343

Family & Domainsi

Sequence similaritiesi

Belongs to the Wnt family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3913 Eukaryota
ENOG410XQZ1 LUCA
GeneTreeiENSGT00760000118943
KOiK00445
OMAiNGGQPQM
OrthoDBiEOG091G0OFF

Family and domain databases

InterProiView protein in InterPro
IPR005817 Wnt
IPR018161 Wnt_CS
PANTHERiPTHR12027 PTHR12027, 1 hit
PfamiView protein in Pfam
PF00110 wnt, 1 hit
PRINTSiPR01349 WNTPROTEIN
SMARTiView protein in SMART
SM00097 WNT1, 1 hit
PROSITEiView protein in PROSITE
PS00246 WNT1, 1 hit

Sequencei

Sequence statusi: Complete.

Q9VM26-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLLMVIAIL IFAMPMTGFG WAEGTNILLD PNLMCKKTRR LRGKLAEICR
60 70 80 90 100
HDSALLKEII INGINLGFRE CEFQFRNRRW NCTVLRKSMR KILMRDSRET
110 120 130 140 150
GFVNAITAAG VTYAVTKACT MGQLVECSCD KAHMRRNGGQ PQMVTAATAE
160 170 180 190 200
AALERQQQAA MLRQQMPLQD QHPSQRLSRM NNASTMTDIA PVEHRGGRNR
210 220 230 240 250
RPGGRRGRRK FWDNIKFPEG QWEWGGCSDN VNFGLRHSRV FLDAKQRQRR
260 270 280 290 300
SDLGTLVKFH NNNAGRLAIR DAMRLECKCH GLSGSCTVKT CWLKMPPFRE
310 320 330 340 350
VAGRLRDRYD SARKVTLRND GNSFMPESPH ARPANKYQLV FADDSPDFCT
360 370 380 390 400
PNSKTGALGT QGRECNVTSS GSDRCDRLCC NRGHTRRIVE EQTNCKCVFK
410 420
WCCEVTCEKC LEHRAVNTCL
Length:420
Mass (Da):47,757
Last modified:June 26, 2013 - v3
Checksum:i4997A0799D604F00
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF52502.3
BT128878 mRNA Translation: AEO01719.1
AE014134 Genomic DNA Translation: AGB92724.1
RefSeqiNP_001260188.1, NM_001273259.1
NP_609108.3, NM_135264.4
UniGeneiDm.23854

Genome annotation databases

EnsemblMetazoaiFBtr0303251; FBpp0292343; FBgn0031902
FBtr0334800; FBpp0306846; FBgn0031902
GeneIDi34010
KEGGidme:Dmel_CG4969
UCSCiCG4969-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ9VM26_DROME
AccessioniPrimary (citable) accession number: Q9VM26
Secondary accession number(s): G2J621
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: June 26, 2013
Last modified: March 28, 2018
This is version 146 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health