Unreviewed, UniProtKB/TrEMBL Q9VM26 (Q9VM26_DROME)

Names and origin

Protein names

Recommended name:
    Protein Wnt RuleBase RU003503V0

Gene names

Name:	Wnt6 FlyBase FBgn0031902
ORF Names:	Dmel_CG4969 EMBL AAF52502.2

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	435 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Ligand for members of the frizzled family of seven transmembrane receptors By similarity. RuleBase RU003500V0
Subcellular location	Secreted › extracellular space › extracellular matrix By similarity. RuleBase RU003500V0
Sequence similarities	Belongs to the Wnt family. RuleBase RU003500V0

Ontologies

Keywords
Biological process	Wnt signaling pathway RuleBase RU003500V0 Spearmint SPM018161
Cellular component	Extracellular matrix Spearmint SPM018161 Secreted
Molecular function	Developmental protein RuleBase RU003500V0 Spearmint SPM018161
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	Wnt receptor signaling pathway, calcium modulating pathway Inferred from electronic annotation. Source: InterPro multicellular organismal development Inferred from electronic annotation. Source: InterPro
Cellular component	proteinaceous extracellular matrix Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	signal transducer activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VM26-1 [UniParc]. Last modified November 13, 2007. Version 2. Checksum: E0F7ED29A96972D7	FASTA	435	49,539
	10 20 30 40 50 60 MGRGIGSDRW RDLRDLKLCW LLFMFADNFA ADFAGKAEGT NILLDPNLMC KKTRRLRGKL 70 80 90 100 110 120 AEICRHDSAL LKEIIINGIN LGFRECEFQF RNRRWNCTVL RKSMRKILMR DSRETGFVNA 130 140 150 160 170 180 ITAAGVTYAV TKACTMGQLV ECSCDKAHMR RNGGQPQMVT AATAEAALER QQQAAMLRQQ 190 200 210 220 230 240 MPLQDQHPSQ RLSRMNNAST MTDIAPVEHR GGRNRRPGGR RGRRKFWDNI KFPEGQWEWG 250 260 270 280 290 300 GCSDNVNFGL RHSRVFLDAK QRQRRSDLGT LVKFHNNNAG RLAIRDAMRL ECKCHGLSGS 310 320 330 340 350 360 CTVKTCWLKM PPFREVAGRL RDRYDSARKV TLRNDGNSFM PESPHARPAN KYQLVFADDS 370 380 390 400 410 420 PDFCTPNSKT GALGTQGREC NVTSSGSDRC DRLCCNRGHT RRIVEEQTNC KCVFKWCCEV 430 TCEKCLEHRA VNTCL

References

[1]

"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.

[2]

"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014134 Genomic DNA. Translation: AAF52502.2.
RefSeq	NP_609108.2.
UniGene	Dm.23854
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	FBgn0031902. Drosophila melanogaster. [Contig view]
GeneID	34010.
KEGG	dme:Dmel_CG4969.
Organism-specific databases
FlyBase	FBgn0031902. Wnt6.
Phylogenomic databases
HOGENOM	Q9VM26.
Gene expression databases
ArrayExpress	Q9VM26.
Family and domain databases
InterPro	IPR005816. Wnt_grthfactor. IPR018161. Wnt_grthfactor_CS. IPR005817. Wnt_SF. [Graphical view]
PANTHER	PTHR12027. Wnt. 1 hit.
Pfam	PF00110. wnt. 1 hit. [Graphical view]
PRINTS	PR01349. WNTPROTEIN.
SMART	SM00097. WNT1. 1 hit. [Graphical view]
PROSITE	PS00246. WNT1. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	786418.

Entry information

Entry name

Q9VM26_DROME

Accession

Primary (citable) accession number: Q9VM26

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	November 13, 2007
Last modified:	June 16, 2009
This is version 62 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)