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Protein

Palmitoyltransferase

Gene

Dnz1

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • lateral inhibition Source: FlyBase
  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
Name:Dnz1Imported
Synonyms:Dmel\CG6627Imported, DNZ1Imported
ORF Names:CG6627Imported, Dmel_CG6627Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0027453. Dnz1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 32HelicalUniRule annotationAdd BLAST21
Transmembranei38 – 57HelicalUniRule annotationAdd BLAST20
Transmembranei150 – 171HelicalUniRule annotationAdd BLAST22
Transmembranei191 – 209HelicalUniRule annotationAdd BLAST19

GO - Cellular componenti

  • endoplasmic reticulum Source: FlyBase
  • integral component of membrane Source: UniProtKB-KW

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiFBgn0027453.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0079770.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini100 – 228DHHCInterPro annotationAdd BLAST129

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1311. Eukaryota.
COG5273. LUCA.
KOiK20029.
OMAiKAVCSDP.
OrthoDBiEOG091G0OGD.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. DHHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9VKN8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVFIRDPCGI ACLVVTYGAV LYADYVVIRW IILTTMPGSL WMSFHVVLFN
60 70 80 90 100
TVVFLLAMSH SKAVFSDPGT VPLPANRLDF SDLHTTNKNN PPPGNGHSSE
110 120 130 140 150
WTVCTRCETY RPPRAHHCRI CKRCIRRMDH HCPWINNCVG ERNQKYFLQF
160 170 180 190 200
LIYVALLSLY SIALIVGSWV WPCEECSQNV IETQLRMIHS VILMLVSALF
210 220 230 240 250
GLFVTAIMVD QLHAILYDET AVEAIQQKGT YRPNRRKYQL LADVFGRGHP
260 270
ALWLLPCTSL NHASRYHDTP LLSHEV
Length:276
Mass (Da):31,529
Last modified:May 1, 2000 - v1
Checksum:i96628EEA9E8A3E9D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA. Translation: AAF53025.1.
AY061178 mRNA. Translation: AAL28726.1.
RefSeqiNP_477449.1. NM_058101.4.
UniGeneiDm.3214.

Genome annotation databases

EnsemblMetazoaiFBtr0080181; FBpp0079770; FBgn0027453.
GeneIDi34503.
KEGGidme:Dmel_CG6627.
UCSCiCG6627-RA. d. melanogaster.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ9VKN8_DROME
AccessioniPrimary (citable) accession number: Q9VKN8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: July 5, 2017
This is version 136 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported