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Q9VK53 (Q9VK53_DROME) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
ACXC, isoform A EMBL AAF53226.2
EC=4.6.1.1 EMBL AAF53226.2
Submitted name:
AT30656p EMBL AAX33597.1
Submitted name:
Adenylyl cyclase ACXC EMBL AAF33109.1
Gene names
Name:ACXC FlyBase FBgn0040508 EMBL AAX33597.1
ORF Names:CG5983 FlyBase FBgn0040508, Dmel_CG5983 EMBL AAF53226.2
OrganismDrosophila melanogaster (Fruit fly)
Taxonomic identifier7227 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length1130 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Ontologies

Keywords
   Molecular functionLyase EMBL AAF53226.2
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processintracellular signal transduction

Inferred from electronic annotation. Source: InterPro

spermatogenesis

Inferred from expression pattern Ref.2. Source: FlyBase

   Molecular functionadenylate cyclase activity

Non-traceable author statement. Source: FlyBase

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q9VK53 [UniParc].

Last modified October 1, 2002. Version 2.
Checksum: B82D7C0DF8FF8568

FASTA1,130129,845
        10         20         30         40         50         60 
MSFPRTNSRK SPLKRKRLRP CHLDYANERL WEHSYLREKC KELNLEEEYR YYQVRLMVSN 

        70         80         90        100        110        120 
LTIFYVLFII LAMSFLTIEL LYVQHYNAVF FNFVIRVVST ILVLTVLSIN FCEKFVSRHR 

       130        140        150        160        170        180 
WVMIASSVLS VYLVVLTDIV MISYHFYKND WPLNTSFDVF TLCMIYMFLP IPSIKGAALL 

       190        200        210        220        230        240 
ASSVSLIYVA FFMHSLTFNA VYTDRDSFGY DVISTDILHN LGFNMMGIFF RIMNDTMVRA 

       250        260        270        280        290        300 
SFLDRHQFIM EETWLRHALL QESILLDSIL PPQIAKPVQE KIKSKITQSE NSPDRFQMGP 

       310        320        330        340        350        360 
RTTESFMAIQ IHPDVSILYA DVVNYTHLTT TLTVGNLVKV LHDLYGRFDI AASNFKVQRI 

       370        380        390        400        410        420 
KFLGDCYYCV AGLTTPDPDH AKCCVSLGIS MISNIQEVRA ERGLDIDMRI GVHSGSLLAG 

       430        440        450        460        470        480 
IIGEAKLQFD IWGTDVEIAN HLESTGEPGY VHVSGRTLSM LNPADYTILS GTQKAQSDPV 

       490        500        510        520        530        540 
LQYIHTYLLT GQVARESFIT SIGGVRSSSV LEVKSIDRIR SSRPSQSSMT DEFREEFRNM 

       550        560        570        580        590        600 
PVGGINLNSP CCRRTRLDTH KKTQREIGIF CAAFKDSSLE WNYLHQPDFI FKSSMLLAWG 

       610        620        630        640        650        660 
IGCCLIYIQI VTNNFSCTAC IVVDLVTFFF LTSLLCLAWY KNVCWWKSGR YEFRIYGKYS 

       670        680        690        700        710        720 
CMAFHIFEKI QHSVSLRITV YLGILFSYYA VISLIMLNCD RDMYELSYIE SKIYHYEMDR 

       730        740        750        760        770        780 
DTCFHPWVFT NMISLILGIS YTFARIPFGL KIVISCCETL AYLLIVFFQF AFIFQHSATT 

       790        800        810        820        830        840 
TPFMKAELAH CLRVCMMLLT MYAKERQSEF NTKMNYKLNV DLQNKQKAAD LTNQSIIILL 

       850        860        870        880        890        900 
NNILPSHVVD LYLNSLAKHE LYYENYRMVS VMFAMLINFP MNLPSLRVLN DIITQFDRLL 

       910        920        930        940        950        960 
TAYREYYVVE KIKVVGCTYM AACGLDFNLA SNIRQTDHFR NSSLHVEVEH ARNHRMTDEN 

       970        980        990       1000       1010       1020 
YDSDMNNDEV VFIMTTFALD LMRTLAACNR AYSSSFFERS LSQGKICIGI SSGEIMAGVV 

      1030       1040       1050       1060       1070       1080 
GASQPHYDIW GNPVNMASRM ESTGLPGHIQ VTEESAKILQ EFDIKCIYRG MTFVKGRGDI 

      1090       1100       1110       1120       1130 
PTYFVGIDEN LKFMSAKLVN RSLSRRFSVM SSLDPDSLRK SSSSDQESGE

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[2]"A new family of adenylyl cyclase genes in the male germline of Drosophila melanogaster."
Cann M.J., Chung E., Levin L.R.
Dev. Genes Evol. 210:200-206(2000) [PubMed: 11180822] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[3]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Berkeley.
[4]Stapleton M., Carlson J., Chavez C., Frise E., George R., Pacleb J., Park S., Wan K., Yu C., Rubin G.M., Celniker S.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF177930 mRNA. Translation: AAF33109.1.
AE014134 Genomic DNA. Translation: AAF53226.2.
BT021449 mRNA. Translation: AAX33597.1.
RefSeqNP_609593.1. NM_135749.2.
UniGeneDm.3283.

3D structure databases

HSSPHSSP built from PDB template 1AZS based on UniProtKB P26769.
ProteinModelPortalQ9VK53.
SMRQ9VK53. Positions 304-490, 862-1086.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ9VK53.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0080413; FBpp0079994; FBgn0040508.
GeneID34689.
KEGGdme:Dmel_CG5983.
NMPDRfig|7227.3.peg.2190.
UCSCCG5983-RA. d. melanogaster.

Organism-specific databases

CTD34689.
FlyBaseFBgn0040508. ACXC.

Phylogenomic databases

GeneTreeEMGT00050000001646.
InParanoidQ9VK53.
OMAKERQTEF.
PhylomeDBQ9VK53.

Gene expression databases

ArrayExpressQ9VK53.
BgeeQ9VK53.

Family and domain databases

InterProIPR001054. A/G_cyclase.
[Graphical view]
Gene3DG3DSA:3.30.70.1230. A/G_cyclase. 2 hits.
KOK01768.
PfamPF00211. Guanylate_cyc. 2 hits.
[Graphical view]
SMARTSM00044. CYCc. 2 hits.
[Graphical view]
SUPFAMSSF55073. A/G_cyclase. 2 hits.
PROSITEPS50125. GUANYLATE_CYCLASE_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio789738.

Entry information

Entry nameQ9VK53_DROME
AccessionPrimary (citable) accession number: Q9VK53
Secondary accession number(s): Q9NJA0
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: October 1, 2002
Last modified: January 25, 2012
This is version 89 of the entry and version 2 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·Ontologies·Sequences·References·Cross-refs·Entry info