Q9VK52 (Q9VK52_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
ACXB EMBL AAF53227.3
EC=4.6.1.1 EMBL AAF53227.3

Gene names

Name:	ACXB
ORF Names:	Dmel_CG17174 EMBL AAF53227.3

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1114 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Lyase EMBL AAF53227.3
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	intracellular signal transduction Inferred from electronic annotation. Source: InterPro spermatogenesis Inferred from expression pattern. Source: FlyBase
Molecular function	adenylate cyclase activity Non-traceable author statement. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VK52 [UniParc]. Last modified October 1, 2002. Version 3. Checksum: C7F60E11C2188EDB	FASTA	1,114	127,704
	10 20 30 40 50 60 MYKKTAYAPR KCYLDYTDER LWERGYLKAK CKELCLEEEY KKYQIRLMIS YLTVFFPLFI 70 80 90 100 110 120 FVVVGCELCP WIFSEQKKLI YYESLTAIVV LVAVPGILSI NFFESFVLRH RWIMVFSSIL 130 140 150 160 170 180 SAYIVVLVDI FQILVFHFKY HWPLNTLYDV FVLCMIYMFL PIPSIRGAAL LATSVSLMYI 190 200 210 220 230 240 GLFIYFLKSD DEDISEVVHD LDTICVDIFH YLGFNLMGIF FRIMNDTMVR SSFLDRHQFL 250 260 270 280 290 300 KEEMWLRQAR QQESMLLDSI LPPQIAKPIQ QSIKERIMLS ETDSDRIVVN ARRTENFMAI 310 320 330 340 350 360 QIHPDVSILY ADVVNYTHLT TTLTVEKLVK VLHDLYGRFD MAASTFKVQR IKFLGDCYYC 370 380 390 400 410 420 VAGLGEADPD HARMAVSLGI SMIANIQEVR AHRALDIDMR IGVHSGTLLA GVIGQAKLQY 430 440 450 460 470 480 DIWGPDVDIA NRLEATGKPG YVHVSGRTLS SLNVAEYTVF PGTEVAQSDP ILQKQPMTTY 490 500 510 520 530 540 LLTAAPSRNS VRSVDAVHSY AEIDINALGA SRKSPILRPT LMSDELREEF KKMPVGGFNI 550 560 570 580 590 600 RSPCCRDNSN DEKVNHGLGM FCVAFKDSSL EWSYLHKPDF ILKYSVLLAW GIGCCLIYIQ 610 620 630 640 650 660 IVNDKFTICV ECIVIDMVVF TFLTSLLFIS WFKKVCWWRC VENDSRKYGR VSCKLFKIWE 670 680 690 700 710 720 RIQHSFVLRV TIYMSIVASY YLLISTILLN CDKNQYELDV INSKLYHYDI VTDNCFNPWV 730 740 750 760 770 780 FTDMISLIVG VSYTFARIPF ALKMLITCCA TVAYLVIVFF QYSFIFEHSA TTTPFMKAEL 790 800 810 820 830 840 AHCLRVCMML LTMYAKERQS EFNTKINFKI NQDLQGKQKA ADITNKSIII LLTNILPSHV 850 860 870 880 890 900 VEVYLDSVAN HELYYENYKM VSVMFAMLIN FQMDLPSLRV LNDIITEFDR LLNAYKEYYV 910 920 930 940 950 960 VEKIKVVGCT YMAACGLDFT LAKSKFGSRT HASYSSELEQ VLYRKESKGT ENDHDEVAFI 970 980 990 1000 1010 1020 MTTFALDLMR VLSVCNKAYA GRPFDRALST GEICIGISTG EIMAGVVGAS QPHYDIWGNP 1030 1040 1050 1060 1070 1080 VNMASRMEST GLPGHIHVTQ ETANILEQFD IMCMYRGMTF VKGRGEIPTY FVGIDDNLKF 1090 1100 1110 LPSNVKKNNM SKRFSILSSL VPVHSRSTTS SEYI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014134 Genomic DNA. Translation: AAF53227.3.
RefSeq	NP_620474.2. NM_138989.2.
UniGene	Dm.3284.
3D structure databases
HSSP	HSSP built from PDB template 1AB8 based on UniProtKB P26769.
ProteinModelPortal	Q9VK52.
SMR	Q9VK52. Positions 294-483, 854-1073.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9VK52.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0080414; FBpp0079995; FBgn0040509.
GeneID	53427.
KEGG	dme:Dmel_CG17174.
NMPDR	fig|7227.3.peg.2191.
UCSC	CG17174-RA. d. melanogaster.
Organism-specific databases
CTD	53427.
FlyBase	FBgn0040509. ACXB.
Phylogenomic databases
GeneTree	EMGT00050000001646.
InParanoid	Q9VK52.
PhylomeDB	Q9VK52.
Gene expression databases
ArrayExpress	Q9VK52.
Bgee	Q9VK52.
Family and domain databases
InterPro	IPR001054. A/G_cyclase. [Graphical view]
Gene3D	G3DSA:3.30.70.1230. A/G_cyclase. 2 hits.
KO	K01768.
Pfam	PF00211. Guanylate_cyc. 2 hits. [Graphical view]
SMART	SM00044. CYCc. 2 hits. [Graphical view]
SUPFAM	SSF55073. A/G_cyclase. 2 hits.
PROSITE	PS50125. GUANYLATE_CYCLASE_2. 2 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	841114.

Entry information

Entry name

Q9VK52_DROME

Accession

Primary (citable) accession number: Q9VK52

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	October 1, 2002
Last modified:	January 25, 2012
This is version 84 of the entry and version 3 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)