Q9VK04 (Q9VK04_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
CG31729, isoform A EMBL AAF53280.2
EC=3.6.3.1 EMBL AAF53280.2

Submitted name:
FI18946p1 EMBL AFH36354.1

Gene names

Name:	CG31729-RA EMBL AFH36354.1
ORF Names:	CG31729 FlyBase FBgn0051729, Dmel_CG31729 EMBL AAF53280.2

Organism

Drosophila melanogaster (Fruit fly) [Reference proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Sophophora › melanogaster group › melanogaster subgroup

Protein attributes

Sequence length	1087 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + H2O + phospholipid(side 1) = ADP + phosphate + phospholipid(side 2). SAAS SAAS018303

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS023306
Ligand	ATP-binding SAAS SAAS023306 Magnesium SAAS SAAS018303 Nucleotide-binding
Molecular function	Hydrolase SAAS SAAS023306 EMBL AAF53280.2
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cation-transporting ATPase activity Inferred from electronic annotation. Source: InterPro magnesium ion binding Inferred from electronic annotation. Source: InterPro phospholipid-translocating ATPase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VK04 [UniParc]. Last modified October 1, 2002. Version 2. Checksum: 1D18ACE858E1FEBD	FASTA	1,087	122,921
	10 20 30 40 50 60 MDDATSQNSA ATPMTRENIP LLNRQRNRWY LFSCWRKWFR PRELRARTVN LGRVNTEKFP 70 80 90 100 110 120 PNEIRNQKYN FITFLPLVLF EQFRFFLNLY FLLMALSQFI PDIRIGYPYT YWGPLGFVLM 130 140 150 160 170 180 VTICREAVDD LRRHQRDHEV NSQKYKRLSS TNISGYEMVP SSKLKVGDVI IVEKNERVPA 190 200 210 220 230 240 DLILLRTSDR SGSVFVRTDQ LDGETDWKPR LAVPYTQKLS RDSELHSIDA SFYVEKPQND 250 260 270 280 290 300 IHSFIATFCM ADGSEDTGLS VENTLWANTV VAAGTATGIV IYTGCETRSV MNNSQPRSKV 310 320 330 340 350 360 GLLDMEINGL TKVLFCAVLG LSLVMMMLKG FGGPWYRYMF RFVLLFSYII PISLRVNLDM 370 380 390 400 410 420 GKAFYSWQMQ NDSNIQGTVV RSTTIPEELG RISYVLTDKT GTLTQNEMVF KKIHLGIVSH 430 440 450 460 470 480 DADTFHHIGQ MIQKLSGNIL QQQQGSLSSS SSGGDSTKPM MFGNRMRRPE GWREWEAVRA 490 500 510 520 530 540 LALCHNVTPV SDDEDNRSVS TASTVTGGNN SPTKSVINIE APGSTDTEHQ YQAASPDEIA 550 560 570 580 590 600 LVKWTEQVGL TLIARDLNTM TLQVKTPSED NDILLHYQIL QLFPFTSESK RMGIIVRESK 610 620 630 640 650 660 TGQITFYLKG ADVVMSSIVQ YNDWLSEESG NMAREGLRTL VVAKKVLTEE QYSDFETRYN 670 680 690 700 710 720 AARLSITDRV AKVAAVTESL ERELELLCLT GVEDRLQENV RPTLELLRNA GVRVWMLTGD 730 740 750 760 770 780 KLETACCIAK SSQLIGRNQG LHVLRSVKTR TDAHQELNSF RRKQGHALVI SGESLEVCLQ 790 800 810 820 830 840 YYRPEFLELA TASPAVVCCR CSPTQKAQVV ALIQKHTGKR TCAVGDGGND VSMIQQADAG 850 860 870 880 890 900 VGIEGREGRQ ASLAGDFSIP QFSHIAKLLL IHGRRSYKRS AALSQFVIHR GLIITTLQAV 910 920 930 940 950 960 FSAVFYLSSV ALYQGFLMVG YSTLYTMFPV FSLVLDQDIT SETAVTYPEL YKDLSKGRSL 970 980 990 1000 1010 1020 SYKTFFIWVL ISIYQGGVIM YGALILFVDE FIHIVAISFS ALIMTELIMV ALTVRTWHRL 1030 1040 1050 1060 1070 1080 MVLAELFSLA LYLISLAVLH EYFDWEFIWS YDFLWKVSLI TLVSCLPLYI IKFLRKKCSP PSYLKLS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: Berkeley.
[3]	Carlson J., Booth B., Frise E., Park S., Wan K., Yu C., Celniker S. Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014134 Genomic DNA. Translation: AAF53280.2. BT133369 mRNA. Translation: AFH36354.1.
RefSeq	NP_723806.1. NM_165038.2.
UniGene	Dm.420.
3D structure databases
SMR	Q9VK04. Positions 145-424, 677-852.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0080462; FBpp0080041; FBgn0051729.
GeneID	34736.
KEGG	dme:Dmel_CG31729.
UCSC	CG31729-RA. d. melanogaster.
Organism-specific databases
FlyBase	FBgn0051729. CG31729.
Phylogenomic databases
GeneTree	ENSGT00550000074723.
InParanoid	Q9VK04.
KO	K01530.
OrthoDB	EOG43R22J.
Family and domain databases
Gene3D	2.70.150.10. 2 hits. 3.40.1110.10. 3 hits. 3.40.50.1000. 2 hits.
InterPro	IPR023299. ATPase_P-typ_cyto_domN. IPR018303. ATPase_P-typ_P_site. IPR006539. ATPase_P-typ_Plipid-transp. IPR008250. ATPase_P-typ_transduc_dom_A. IPR001757. Cation_transp_P_typ_ATPase. IPR023214. HAD-like_dom. [Graphical view]
PANTHER	PTHR24092. PTHR24092. 1 hit.
Pfam	PF00122. E1-E2_ATPase. 1 hit. PF00702. Hydrolase. 1 hit. [Graphical view]
PRINTS	PR00119. CATATPASE.
SUPFAM	SSF81660. ATPase_cation_domN. 1 hit. SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01652. ATPase-Plipid. 1 hit. TIGR01494. ATPase_P-type. 2 hits.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	34736.
NextBio	789961.

Entry information

Entry name

Q9VK04_DROME

Accession

Primary (citable) accession number: Q9VK04

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	October 1, 2002
Last modified:	May 1, 2013
This is version 108 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)