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Protein

Angiotensin-converting enzyme

Gene

Ance-2

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionCarboxypeptidaseUniRule annotationImported, Hydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Angiotensin-converting enzymeUniRule annotation (EC:3.4.-.-UniRule annotation)
Gene namesi
Name:Ance-2Imported
Synonyms:ance-2Imported, CG31844Imported, Dmel\CG16869Imported
ORF Names:CG16869Imported, Dmel_CG16869Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0032535 Ance-2

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15Sequence analysisAdd BLAST15
ChainiPRO_501233907716 – 611Angiotensin-converting enzymeSequence analysisAdd BLAST596

Keywords - PTMi

GlycoproteinUniRule annotation

Proteomic databases

PaxDbiQ9VJV2
PRIDEiQ9VJV2

Expressioni

Gene expression databases

BgeeiFBgn0032535
GenevisibleiQ9VJV2 DM

Interactioni

Protein-protein interaction databases

IntActiQ9VJV2, 3 interactors
STRINGi7227.FBpp0080131

Structurei

3D structure databases

ProteinModelPortaliQ9VJV2
SMRiQ9VJV2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3690 Eukaryota
ENOG410XPJ3 LUCA
GeneTreeiENSGT00520000055576
InParanoidiQ9VJV2
KOiK01283
OMAiDDQYASN
OrthoDBiEOG091G03PX
PhylomeDBiQ9VJV2

Family and domain databases

InterProiView protein in InterPro
IPR001548 Peptidase_M2
PANTHERiPTHR10514 PTHR10514, 1 hit
PfamiView protein in Pfam
PF01401 Peptidase_M2, 1 hit
PRINTSiPR00791 PEPDIPTASEA

Sequencei

Sequence statusi: Complete.

Q9VJV2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWIFAVLLLV GLTQAGSQPD ATLERFLNET NQQLAVIYDQ AVLAQLLNEL
60 70 80 90 100
RGPNDLVALL EIEVTDDKLV KYVRTLTTRK AKFKRLGLGD SRQRRLLDKI
110 120 130 140 150
PQLGYEALSG RDLKLVYALA SSMSDNYHNV KLCAYKQPGN CTLRLIPEVQ
160 170 180 190 200
SIVQGSRDLD EIEYYWFEWR SRTGLATRSQ FVDFMDLYKK TAQLNGYPRA
210 220 230 240 250
EDYWFRSLEL KGQETMNLLD RIMHGLRPLF LQFHAHVRGS LRKMHGEHLV
260 270 280 290 300
PRNRPYPQHL AEVFIGNAFR RVEAEWYVDL PSPEIGLANI TQELHRRGLS
310 320 330 340 350
TTQRVFWNVA EYFRALGFPQ LENSLWTYAQ KVSSDDDDRC WHKAWRYYAL
360 370 380 390 400
PRTNFTYCPL NDEERFFNMF EAQSDLQYYR AASIQPTLLQ EEPFPNFSDA
410 420 430 440 450
IGKCFSMAAS SPRFLRKLGM LRDNKWKELP ARLNRLYIQG LRVVFLLPVF
460 470 480 490 500
YVLDRYRVEV LAGHIKADDN EAYWRLTELY TGAAAPTKRT NEQFDVPAKL
510 520 530 540 550
LMEVDDQYAS NFLSIVLQFQ LLKHFCTITG QFEMGNPRKP LDMCDLSDQR
560 570 580 590 600
GIGEILKRAM SLGSSVHYRE VLKVLLGEPE ISIDGLLTYF QPLQDWLQHQ
610
NQENNLEVGW T
Length:611
Mass (Da):71,133
Last modified:May 1, 2000 - v1
Checksum:i9234325B2082DBA8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF53354.1
RefSeqiNP_788042.1, NM_176028.2

Genome annotation databases

EnsemblMetazoaiFBtr0080554; FBpp0080131; FBgn0032535
GeneIDi34806
KEGGidme:Dmel_CG16869
UCSCiCG16869-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ9VJV2_DROME
AccessioniPrimary (citable) accession number: Q9VJV2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: March 28, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health