Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

LD25692p

Gene

l(2)37Cb

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • ATP-dependent RNA helicase activity Source: FlyBase
  • RNA binding Source: GO_Central

GO - Biological processi

  • mRNA splicing, via spliceosome Source: FlyBase

Keywordsi

Molecular functionHydrolaseSAAS annotationImported
LigandATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DME-72163. mRNA Splicing - Major Pathway.

Names & Taxonomyi

Protein namesi
Submitted name:
LD25692pImported
Submitted name:
Lethal (2) 37CbImported (EC:3.6.1.3Imported)
Gene namesi
Name:l(2)37CbImported
Synonyms:CbImported, Dmel\CG10689Imported, l(2)E104Imported
ORF Names:CG10689Imported, Dmel_CG10689Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0086444. l(2)37Cb.

Subcellular locationi

GO - Cellular componenti

  • catalytic step 2 spliceosome Source: FlyBase
  • cytoplasm Source: GO_Central
  • precatalytic spliceosome Source: FlyBase
  • spliceosomal complex Source: FlyBase

Expressioni

Gene expression databases

BgeeiFBgn0086444.

Interactioni

Protein-protein interaction databases

IntActiQ9VIZ3. 3 interactors.
MINTiMINT-318410.
STRINGi7227.FBpp0080706.

Structurei

3D structure databases

SMRiQ9VIZ3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini262 – 426Helicase ATP-bindingInterPro annotationAdd BLAST165
Domaini451 – 624Helicase C-terminalInterPro annotationAdd BLAST174

Phylogenomic databases

eggNOGiKOG0925. Eukaryota.
COG1643. LUCA.
GeneTreeiENSGT00880000137867.
KOiK12813.
OMAiVYNQWVE.
OrthoDBiEOG091G030Q.

Family and domain databases

InterProiView protein in InterPro
IPR002464. DNA/RNA_helicase_DEAH_CS.
IPR011709. DUF1605.
IPR007502. Helicase-assoc_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF04408. HA2. 1 hit.
PF00271. Helicase_C. 1 hit.
PF07717. OB_NTP_bind. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00847. HA2. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00690. DEAH_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9VIZ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGKNRKRTA SSSSSGEEPD SEEESRLKDL QERDEFASRL KKRDDDRTRN
60 70 80 90 100
VVDSTGGRRA IEEATKRLKL EHEDRDKIVP HLRLQSRRQY LEKRKDDKVA
110 120 130 140 150
ELEADILDDE YLFDESVLTK REKEEREYKK QLLNIAKEHE KARELERIQR
160 170 180 190 200
YNMPQDLKKG ERSEYVEVDE FEKQPNSEQK KWEAEQLASA RFHFGAKDAK
210 220 230 240 250
AEEEYELLLD DQIDFIQALT LDGSREKSSS RQPELTEKER KRLTLDETRR
260 270 280 290 300
SLPVYPFKED LIAAVKEHQV LIIEGETGSG KTTQVPQYLV EAGFTKDKKM
310 320 330 340 350
IGCTQPRRVA AMSVAARVAE EMGVKLGNEV GYSIRFEDCT SDRTILKYMT
360 370 380 390 400
DGTLHREFLS EPDLASYSVM IIDEAHERTL HTDILFGLVK DIARFRPELK
410 420 430 440 450
LLISSATLDA EKFSAFFDDA PIFRIPGRRY PVDIFYTKAP EADYIDACCV
460 470 480 490 500
SVLQIHATQP LGDILVFLTG QDEIETCQEV LHDRVKRLGS KIRELIVIPV
510 520 530 540 550
YANLPSDMQA KIFEPTPPNA RKVILATNIA ETSLTIDNII YVIDPGFAKQ
560 570 580 590 600
NNFNSRTGME SLMVVPISKA SANQRAGRAG RTAPGKCFRL YTAWAYKHEL
610 620 630 640 650
EDNTVPEIQR INLGNAVLML KALGINDLIH FDFLDPPPHE TLVLALEQLY
660 670 680 690 700
ALGALNHHGE LTKLGRRMAE FPVDPMMGKM LLASEKYKCS EEMVTIAAML
710 720 730 740 750
SVNSAIFYRP KDKIIHADTA RKNFNHMHGD HLSLLQVYNQ WAETDYSTQW
760 770 780 790 800
CYENFIQYRS MKRARDVREQ LVGLMQRVEI DMVSCLPETV NVRKAATAGY
810 820 830 840 850
FYHVARLSKG GHYKTIKHNQ TVMIHPNSSL FEELPRWVLY HELVFTSKEY
860 870 880 890
MRQVIEIESK WLLEVAPHYY KAKELEDSTN KKMPKVAGRA EMAQ
Length:894
Mass (Da):102,833
Last modified:May 1, 2000 - v1
Checksum:i3A3755BF40C0D77C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA. Translation: AAF53766.1.
AY061330 mRNA. Translation: AAL28878.1.
RefSeqiNP_609946.1. NM_136102.4.
UniGeneiDm.468.

Genome annotation databases

EnsemblMetazoaiFBtr0081163; FBpp0080706; FBgn0086444.
GeneIDi35192.
KEGGidme:Dmel_CG10689.
UCSCiCG10689-RA. d. melanogaster.

Similar proteinsi

Entry informationi

Entry nameiQ9VIZ3_DROME
AccessioniPrimary (citable) accession number: Q9VIZ3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: August 30, 2017
This is version 157 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported