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Protein
Submitted name:

Cytochrome c oxidase subunit 4, isoform A

Gene

COX4

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cell proliferation Source: FlyBase
  • Golgi organization Source: FlyBase
  • mitochondrial electron transport, cytochrome c to oxygen Source: FlyBase
  • mitotic cell cycle Source: FlyBase
  • negative regulation of neuroblast proliferation Source: FlyBase

Keywordsi

Molecular functionOxidoreductaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome c oxidase subunit 4, isoform AImported (EC:1.9.3.1Imported)
Submitted name:
Cytochrome c oxidase subunit 4, isoform BImported
Submitted name:
Cytochrome c oxidase subunit 4, isoform CImported
Submitted name:
Cytochrome c oxidase subunit 4, isoform DImported
Submitted name:
GM14452pImported
Submitted name:
MIP33903p1Imported
Gene namesi
Name:COX4Imported
Synonyms:C-IV s.4Imported, CcO IVImported, CG10664-RBImported, CoIVImported, COXImported, COX IVImported, Cox4Imported, cox4Imported, COXIVImported, CoxIVImported, CX41Imported, CX42Imported, dCOX-IVImported, Dmel\CG10664Imported, IVImported
ORF Names:CG10664Imported, Dmel_CG10664Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0032833 COX4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei117 – 139HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiFBgn0032833

Interactioni

Protein-protein interaction databases

IntActiQ9VIQ8, 3 interactors
STRINGi7227.FBpp0080836

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4075 Eukaryota
ENOG4111T97 LUCA
GeneTreeiENSGT00390000002407
KOiK02263
OMAiAMQTKRM
OrthoDBiEOG091G0XDH

Family and domain databases

CDDicd00922 Cyt_c_Oxidase_IV, 1 hit
Gene3Di1.10.442.10, 1 hit
InterProiView protein in InterPro
IPR013288 Cyt_c_oxidase_su4
IPR004203 Cyt_c_oxidase_su4_fam
IPR036639 Cyt_c_oxidase_su4_sf
PANTHERiPTHR10707 PTHR10707, 1 hit
PfamiView protein in Pfam
PF02936 COX4, 1 hit
PRINTSiPR01873 CYTCOXIDASE4
SUPFAMiSSF81406 SSF81406, 1 hit

Sequencei

Sequence statusi: Complete.

Q9VIQ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALRLLNSAV LRQLASQLPK SAQVGSVAAV HTLDKIGKRE IVGYGWNGTA
60 70 80 90 100
CYADRVDYPL PAVRFREPTN EINALRAKEQ GDWKKLSTQE IKALYRASFC
110 120 130 140 150
QTIAEVQAGS GEWKLHLGVS LLFCAAAIWV AVLMNIFVYD ELPVTFDEEH
160 170 180
QKAQLQRIID LEINPVTGLT SKWDYENKKW KN
Length:182
Mass (Da):20,520
Last modified:May 1, 2000 - v1
Checksum:i6D5953D8DE41217A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF53857.1
AY058491 mRNA Translation: AAL13720.1
AE014134 Genomic DNA Translation: AAS64725.1
BT149857 mRNA Translation: AFP43247.1
AE014134 Genomic DNA Translation: AGB93147.1
AE014134 Genomic DNA Translation: AGB93148.1
RefSeqiNP_001260612.1, NM_001273683.1
NP_001260613.1, NM_001273684.1
NP_610013.1, NM_136169.4
NP_995732.1, NM_206010.3
UniGeneiDm.4187

Genome annotation databases

EnsemblMetazoaiFBtr0081300; FBpp0080835; FBgn0032833
FBtr0081301; FBpp0080836; FBgn0032833
FBtr0332242; FBpp0304537; FBgn0032833
FBtr0332243; FBpp0304538; FBgn0032833
GeneIDi35279
KEGGidme:Dmel_CG10664
UCSCiCG10664-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ9VIQ8_DROME
AccessioniPrimary (citable) accession number: Q9VIQ8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 152 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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