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Protein
Submitted name:

Cytochrome c oxidase subunit 4, isoform A

Gene

COX4

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cell proliferation Source: FlyBase
  • Golgi organization Source: FlyBase
  • mitochondrial electron transport, cytochrome c to oxygen Source: FlyBase
  • mitotic cell cycle Source: FlyBase
  • negative regulation of neuroblast proliferation Source: FlyBase

Keywordsi

Molecular functionOxidoreductaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome c oxidase subunit 4, isoform AImported (EC:1.9.3.1Imported)
Submitted name:
Cytochrome c oxidase subunit 4, isoform BImported
Submitted name:
Cytochrome c oxidase subunit 4, isoform CImported
Submitted name:
Cytochrome c oxidase subunit 4, isoform DImported
Submitted name:
GM14452pImported
Submitted name:
MIP33903p1Imported
Gene namesi
Name:COX4Imported
Synonyms:C-IV s.4Imported, CcO IVImported, CG10664-RBImported, CoIVImported, COXImported, COX IVImported, Cox4Imported, cox4Imported, COXIVImported, CoxIVImported, CX41Imported, CX42Imported, dCOX-IVImported, Dmel\CG10664Imported, IVImported
ORF Names:CG10664Imported, Dmel_CG10664Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0032833. COX4.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei117 – 139HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiFBgn0032833.

Interactioni

Protein-protein interaction databases

IntActiQ9VIQ8. 9 interactors.
MINTiMINT-304296.
STRINGi7227.FBpp0080836.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4075. Eukaryota.
ENOG4111T97. LUCA.
GeneTreeiENSGT00390000002407.
KOiK02263.
OMAiAMQTKRM.
OrthoDBiEOG091G0XDH.

Family and domain databases

CDDicd00922. Cyt_c_Oxidase_IV. 1 hit.
InterProiView protein in InterPro
IPR013288. Cyt_c_oxidase_su4.
IPR004203. Cyt_c_oxidase_su4_fam.
PANTHERiPTHR10707. PTHR10707. 1 hit.
PfamiView protein in Pfam
PF02936. COX4. 1 hit.
PRINTSiPR01873. CYTCOXIDASE4.
SUPFAMiSSF81406. SSF81406. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9VIQ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALRLLNSAV LRQLASQLPK SAQVGSVAAV HTLDKIGKRE IVGYGWNGTA
60 70 80 90 100
CYADRVDYPL PAVRFREPTN EINALRAKEQ GDWKKLSTQE IKALYRASFC
110 120 130 140 150
QTIAEVQAGS GEWKLHLGVS LLFCAAAIWV AVLMNIFVYD ELPVTFDEEH
160 170 180
QKAQLQRIID LEINPVTGLT SKWDYENKKW KN
Length:182
Mass (Da):20,520
Last modified:May 1, 2000 - v1
Checksum:i6D5953D8DE41217A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA. Translation: AAF53857.1.
AY058491 mRNA. Translation: AAL13720.1.
AE014134 Genomic DNA. Translation: AAS64725.1.
BT149857 mRNA. Translation: AFP43247.1.
AE014134 Genomic DNA. Translation: AGB93147.1.
AE014134 Genomic DNA. Translation: AGB93148.1.
RefSeqiNP_001260612.1. NM_001273683.1.
NP_001260613.1. NM_001273684.1.
NP_610013.1. NM_136169.4.
NP_995732.1. NM_206010.3.
UniGeneiDm.4187.

Genome annotation databases

EnsemblMetazoaiFBtr0081300; FBpp0080835; FBgn0032833.
FBtr0081301; FBpp0080836; FBgn0032833.
FBtr0332242; FBpp0304537; FBgn0032833.
FBtr0332243; FBpp0304538; FBgn0032833.
GeneIDi35279.
KEGGidme:Dmel_CG10664.
UCSCiCG10664-RA. d. melanogaster.

Similar proteinsi

Entry informationi

Entry nameiQ9VIQ8_DROME
AccessioniPrimary (citable) accession number: Q9VIQ8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: September 27, 2017
This is version 144 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported