Unreviewed, UniProtKB/TrEMBL Q9VIA4 (Q9VIA4_DROME)

Names and origin

Protein names

Submitted name:
    MstProx EMBL AAF54021.3

Gene names

Name:	MstProx EMBL AAF54021.3
ORF Names:	Dmel_CG1149 EMBL AAF54021.3

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	965 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the TGF-beta family. RuleBase RU000354V2 Contains 1 TIR domain. Spearmint SPM000157

Ontologies

Keywords
Cellular component	Membrane
Domain	Leucine-rich repeat Spearmint SPM000157 Repeat Spearmint SPM000157 Transmembrane Spearmint SPM000157
Molecular function	Growth factor RuleBase RU000354V2
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	innate immune response Inferred from electronic annotation. Source: InterPro signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	intrinsic to membrane Inferred from electronic annotation. Source: InterPro
Molecular function	protein binding Inferred from electronic annotation. Source: InterPro transmembrane receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VIA4-1 [UniParc]. Last modified May 24, 2005. Version 3. Checksum: D2311AB2F8A79127	FASTA	965	112,475
	10 20 30 40 50 60 MKLLLTIPDD YCETYCGGIC NDTVASKTCD REAYDYIATN EYHLIMRDGH LEVNWKIPDP 70 80 90 100 110 120 NIFIISPISK ENRLKLNELI VSDTSYPIRA VDYLRQLGVE TVTRFENQIN SFKVIERDVH 130 140 150 160 170 180 YINGPKSLKI IIQSNLYLNE IIEYINKTTD NVNEIIINAY KTVENQQIAL DNLIFNGKSH 190 200 210 220 230 240 LRSLTFIGFQ IENLSTKPFA QFINLKRMVL TNCTVRNLTF LRTLQKSLEH LELDIDNEVD 250 260 270 280 290 300 LKYFTNFSSL KFMKVRNYIP NKNFTALICT HKNCNFIRGI NGLECPKLCQ CLYIIDDLEL 310 320 330 340 350 360 NIDCSNLGLL QIPPLPIPSY GGVKLNFSNN SLSQLPTMTL PGYKLVKRLD VSRNRLTNLS 370 380 390 400 410 420 INHLPAKLDY LDVSFNEIIN MGNDVIKYLR TVPIFKQTGN QWTIHCDDKP LLNFFRHLKL 430 440 450 460 470 480 IIRMKSAEMK PMFLHSLTEL PKGFLKFLGK HFIWLGVRKQ EYYLINEEQL LQSMHRKLNN 490 500 510 520 530 540 LNTIMSIYKY MEWLHRKLIF VNREYDLFYI RQMAAPCPHK CECCYSRDSL ILKIDCRNKF 550 560 570 580 590 600 VYNFPDIVAR NSRLMGKQNM SSPMELHLSK NNISNITIAM LPKELRFLDL RFNNLVTLDD 610 620 630 640 650 660 KVLSYLKKNS IKTKLSGNPW NCDCKSRSVL SILRDHEPLE YDVTLKRCNI SPTDCPDVCV 670 680 690 700 710 720 CCLDNLTWPS FIVDCRGEGL LQMPSLSSRV TYVDLRNNNL TALSQKNRSS IENRSLKLHL 730 740 750 760 770 780 LDNPWSCSCN DIEKINFMKS VSSSIVDFTE IKCSNGEKLV SINQHIVCPS DLFYYLALAI 790 800 810 820 830 840 SLVATIIALN FLIWFRQPVL VWFYEHGVCL SLSAKRELDK DKRFDAFLAF THKDEALLEE 850 860 870 880 890 900 FVDRLERGRP RFQLCFYLRD WLAGESIPDC IGQSIKDSRR IIVLMTENFM NSTWGRLEFR 910 920 930 940 950 960 LALHATSRDR CKRLIVVLYP NVKNFDSLDS ELRTYMAFNT YLERSHPNFW NKLIYSMPLL PSYVD

References

[1]

"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.

[2]

"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014297 Genomic DNA. Translation: AAF54021.3.
RefSeq	NP_649719.2.
UniGene	Dm.3402
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	FBgn0015770. Drosophila melanogaster. [Contig view]
GeneID	40890.
KEGG	dme:Dmel_CG1149.
Organism-specific databases
FlyBase	FBgn0015770. MstProx.
Phylogenomic databases
HOGENOM	Q9VIA4.
Gene expression databases
ArrayExpress	Q9VIA4.
Family and domain databases
InterPro	IPR004075. IL1_rcpt_1. IPR001611. Leu-rich_rpt. IPR000372. Leu-rich_rpt_Cys-rich-reg_N. IPR017948. TGFb_CS. IPR000157. Toll-Interleukin_rcpt. [Graphical view]
Pfam	PF00560. LRR_1. 1 hit. PF01462. LRRNT. 1 hit. PF01582. TIR. 1 hit. [Graphical view]
PRINTS	PR01537. INTRLKN1R1F.
SMART	SM00013. LRRNT. 3 hits. SM00255. TIR. 1 hit. [Graphical view]
PROSITE	PS00250. TGF_BETA_1. 1 hit. Uncertain. PS50104. TIR. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	821143.

Entry information

Entry name

Q9VIA4_DROME

Accession

Primary (citable) accession number: Q9VIA4
Secondary accession number(s): Q24164

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 24, 2005
Last modified:	June 16, 2009
This is version 57 of the entry and version 3 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)