Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cytochrome c oxidase subunit 7A, mitochondrial

Gene

COX7A

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.By similarity

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 7A, mitochondrial (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase subunit VIIa
Gene namesi
Name:COX7AImported
ORF Names:CG9603Imported
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0040529. COX7A.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 31MitochondrionSequence analysisAdd BLAST31
ChainiPRO_000000615332 – 89Cytochrome c oxidase subunit 7A, mitochondrialAdd BLAST58

Proteomic databases

PaxDbiQ9VHS2.
PRIDEiQ9VHS2.

Expressioni

Gene expression databases

BgeeiFBgn0040529.
ExpressionAtlasiQ9VHS2. differential.
GenevisibleiQ9VHS2. DM.

Interactioni

Protein-protein interaction databases

BioGridi72497. 2 interactors.
DIPiDIP-17309N.
IntActiQ9VHS2. 3 interactors.
MINTiMINT-744456.
STRINGi7227.FBpp0296960.

Structurei

3D structure databases

ProteinModelPortaliQ9VHS2.
SMRiQ9VHS2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome c oxidase VIIa family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiENOG410JMEB. Eukaryota.
ENOG410ZTB2. LUCA.
InParanoidiQ9VHS2.
KOiK02270.
OrthoDBiEOG091G1BBJ.
PhylomeDBiQ9VHS2.

Family and domain databases

CDDicd00928. Cyt_c_Oxidase_VIIa. 1 hit.
InterProiView protein in InterPro
IPR003177. Cyt_c_oxidase_su7a.
PANTHERiPTHR10510. PTHR10510. 1 hit.
SUPFAMiSSF81419. SSF81419. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9VHS2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMNLSRAVVR SFATTAGRRS AAVPKDQIEK GYFEIRKVQE HFQKKDGKPV
60 70 80
FLKGSVVDNV LYRVTVALAL VGIGGMGKLF YELSVPKKE
Length:89
Mass (Da):9,902
Last modified:May 1, 2000 - v1
Checksum:i9220331ED2D07F20
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAF54227.1.
BT058048 mRNA. Translation: ACM78490.1.
RefSeqiNP_652184.2. NM_143927.4.
UniGeneiDm.6020.

Genome annotation databases

EnsemblMetazoaiFBtr0081855; FBpp0081344; FBgn0040529.
GeneIDi50002.
KEGGidme:Dmel_CG9603.
UCSCiCG9603-RA. d. melanogaster.

Similar proteinsi

Entry informationi

Entry nameiCOX7A_DROME
AccessioniPrimary (citable) accession number: Q9VHS2
Secondary accession number(s): B9EQX3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: September 27, 2017
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families