Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9VHS2

- COX7A_DROME

UniProt

Q9VHS2 - COX7A_DROME

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable cytochrome c oxidase subunit 7A, mitochondrial

Gene

CG9603

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.By similarity

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cytochrome c oxidase subunit 7A, mitochondrial (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase subunit VIIa
Gene namesi
ORF Names:CG9603
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000000803: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0040529. CG9603.

Subcellular locationi

GO - Cellular componenti

  1. mitochondrial respiratory chain Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 3131MitochondrionSequence AnalysisAdd
BLAST
Chaini32 – 8958Probable cytochrome c oxidase subunit 7A, mitochondrialPRO_0000006153Add
BLAST

Proteomic databases

PaxDbiQ9VHS2.
PRIDEiQ9VHS2.

Expressioni

Gene expression databases

BgeeiQ9VHS2.
ExpressionAtlasiQ9VHS2. differential.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
BcDNA.GH11688Q9Y1041EBI-105449,EBI-97789

Protein-protein interaction databases

BioGridi72497. 1 interaction.
DIPiDIP-17309N.
IntActiQ9VHS2. 1 interaction.
MINTiMINT-744456.

Structurei

3D structure databases

ProteinModelPortaliQ9VHS2.
SMRiQ9VHS2. Positions 33-88.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome c oxidase VIIa family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiNOG118447.
InParanoidiQ9VHS2.
KOiK02270.
OrthoDBiEOG7J182H.
PhylomeDBiQ9VHS2.

Family and domain databases

Gene3Di4.10.91.10. 1 hit.
InterProiIPR003177. Cyt_c_oxidase_su7a.
[Graphical view]
PANTHERiPTHR10510. PTHR10510. 1 hit.
PfamiPF02238. COX7a. 1 hit.
[Graphical view]
SUPFAMiSSF81419. SSF81419. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9VHS2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMNLSRAVVR SFATTAGRRS AAVPKDQIEK GYFEIRKVQE HFQKKDGKPV
60 70 80
FLKGSVVDNV LYRVTVALAL VGIGGMGKLF YELSVPKKE
Length:89
Mass (Da):9,902
Last modified:May 1, 2000 - v1
Checksum:i9220331ED2D07F20
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAF54227.1.
BT058048 mRNA. Translation: ACM78490.1.
RefSeqiNP_652184.2. NM_143927.4.
UniGeneiDm.6020.

Genome annotation databases

EnsemblMetazoaiFBtr0081855; FBpp0081344; FBgn0040529.
GeneIDi50002.
KEGGidme:Dmel_CG9603.
UCSCiCG9603-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAF54227.1 .
BT058048 mRNA. Translation: ACM78490.1 .
RefSeqi NP_652184.2. NM_143927.4.
UniGenei Dm.6020.

3D structure databases

ProteinModelPortali Q9VHS2.
SMRi Q9VHS2. Positions 33-88.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 72497. 1 interaction.
DIPi DIP-17309N.
IntActi Q9VHS2. 1 interaction.
MINTi MINT-744456.

Proteomic databases

PaxDbi Q9VHS2.
PRIDEi Q9VHS2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0081855 ; FBpp0081344 ; FBgn0040529 .
GeneIDi 50002.
KEGGi dme:Dmel_CG9603.
UCSCi CG9603-RA. d. melanogaster.

Organism-specific databases

FlyBasei FBgn0040529. CG9603.

Phylogenomic databases

eggNOGi NOG118447.
InParanoidi Q9VHS2.
KOi K02270.
OrthoDBi EOG7J182H.
PhylomeDBi Q9VHS2.

Miscellaneous databases

ChiTaRSi CG9603. fly.
GenomeRNAii 50002.
NextBioi 840015.

Gene expression databases

Bgeei Q9VHS2.
ExpressionAtlasi Q9VHS2. differential.

Family and domain databases

Gene3Di 4.10.91.10. 1 hit.
InterProi IPR003177. Cyt_c_oxidase_su7a.
[Graphical view ]
PANTHERi PTHR10510. PTHR10510. 1 hit.
Pfami PF02238. COX7a. 1 hit.
[Graphical view ]
SUPFAMi SSF81419. SSF81419. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Drosophila melanogaster."
    Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
    , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
    Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  2. Cited for: GENOME REANNOTATION.
    Strain: Berkeley.
  3. Carlson J.W., Booth B., Frise E., Park S., Wan K.H., Yu C., Celniker S.E.
    Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Berkeley.
    Tissue: Ovary.

Entry informationi

Entry nameiCOX7A_DROME
AccessioniPrimary (citable) accession number: Q9VHS2
Secondary accession number(s): B9EQX3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: November 26, 2014
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3