Unreviewed, UniProtKB/TrEMBL Q9VHA1 (Q9VHA1_DROME)

Names and origin

Protein names

Submitted name:
    Spermidine synthase, isoform A EMBL AAF54417.1
    EC=2.5.1.16 EMBL AAF54417.1

Gene names

Name:	SpdS EMBL AAF54417.1
ORF Names:	Dmel_CG8327 EMBL AAF54417.1

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	287 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the spermidine/spermine synthase family. RuleBase RU003836V0

Ontologies

Keywords
Molecular function	Transferase RuleBase RU003836V0
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	protein binding Inferred from physical interaction. Source: IntAct spermidine synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
Aats-gln	Q9Y105	1	EBI-154429,EBI-109039

Sequences

	Sequence		Length	Mass (Da)
	Q9VHA1-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 80EE950E91B193F9	FASTA	287	32,335
	10 20 30 40 50 60 MDSLNNGWFS ELQADLWPGQ SFSLKVKEVI HKEKSRFQDI QIVETETYGR CLILDGIIQC 70 80 90 100 110 120 TARDEFSYQE MISFLPLCAH PNPKKVLIVG GGDGGVAREV VKHPLVEEVH QVEIDDRVVE 130 140 150 160 170 180 LSKQYLPAMA CGFANEKLKL TIGDGFDYMK KHKNEFDVII TDSSDPIGPA VSLFQESYYE 190 200 210 220 230 240 LMKHALKDDG IVCSQGGSFW LDLDYIKKTM SGCKEHFAKV AYAVTSVPSY PCGHIGFVMG 250 260 270 280 SLNKNQDFAT PKLGKSEIDS IDLRYYSSEV HSAAFALPRW VQKHFYE

References

[1]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014297 Genomic DNA. Translation: AAF54417.1.
RefSeq	NP_731384.1.
UniGene	Dm.20162
3D structure databases
HSSP	HSSP built from PDB template 1INL based on UniProtKB Q9WZC2.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9VHA1. 1 interaction.
STRING	Q9VHA1.
Proteomic databases
PRIDE	Q9VHA1.
Genome annotation databases
Ensembl	FBtr0082078; FBpp0081556; FBgn0037723; Drosophila melanogaster. [Genome view] FBtr0082079; FBpp0081557; FBgn0037723; Drosophila melanogaster. [Genome view]
GeneID	41167.
UCSC	CG8327-RA. d. melanogaster.
Organism-specific databases
CTD	41167.
FlyBase	FBgn0037723. SpdS.
Phylogenomic databases
InParanoid	Q9VHA1.
OMA	MEPGPDG.
OrthoDB	EOG9DJK38.
PhylomeDB	Q9VHA1.
Gene expression databases
ArrayExpress	Q9VHA1.
Family and domain databases
InterPro	IPR001045. Sprmine_synthase. [Graphical view]
PANTHER	PTHR11558. Sprmine_synthase. 1 hit.
Pfam	PF01564. Spermine_synth. 1 hit. [Graphical view]
TIGRFAMs	TIGR00417. speE. 1 hit.
PROSITE	PS01330. SPERMIDINE_SYNTHASE_1. 1 hit. PS51006. SPERMIDINE_SYNTHASE_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	Dmel_CG8327. 822519.

Entry information

Entry name

Q9VHA1_DROME

Accession

Primary (citable) accession number: Q9VHA1

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	December 15, 2009
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)