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Q9VGC3 (COG1_DROME) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Conserved oligomeric Golgi complex subunit 1
Short name=COG complex subunit 1
Alternative name(s):
Component of oligomeric Golgi complex 1
Gene names
ORF Names:CG4848
OrganismDrosophila melanogaster (Fruit fly)
Taxonomic identifier7227 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length886 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Required for normal Golgi function By similarity.

Subunit structure

Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization By similarity.

Subcellular location

Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side By similarity.

Sequence similarities

Belongs to the COG1 family.

Ontologies

Keywords
   Biological processProtein transport
Transport
   Cellular componentGolgi apparatus
Membrane
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processprotein transport

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentGolgi membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 886886Conserved oligomeric Golgi complex subunit 1
PRO_0000213493

Amino acid modifications

Modified residue8391Phosphoserine Ref.4

Sequences

Sequence LengthMass (Da)Tools
Q9VGC3 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 2DE97D584476FBC8

FASTA88699,716
        10         20         30         40         50         60 
MTANLLNLNV DTLFEQHSVS EIDEVHKKIQ SVVENKREEL RTHVGERYRD LLQAADTIAA 

        70         80         90        100        110        120 
MQTSAGTLME QVRHVQANCR SLNEQQLLGF QSTANASAKD AALKERNAGK KLQTYYGTMA 

       130        140        150        160        170        180 
QIKLLTALPE LIWTHLDNDR FYAATELFIF SRHISTGLQL DGQSALMQKL PVARKQWEIL 

       190        200        210        220        230        240 
RPFHVTIKQA ILTALEREEL LQEMTVDCLQ SLLLLDKSDL STVLKSFLNL RSSAFLNCLQ 

       250        260        270        280        290        300 
SGPSEPRRVK DRILASLNVL NSTVELLDKC LLGYSLLFSR LEECASSTCP PSINRMESSE 

       310        320        330        340        350        360 
RQLVHLLPEI IAGFKPQFDV PQLTPEQLGS SLQQWLDKMN ALAAAHLQQV FALVTNMQTI 

       370        380        390        400        410        420 
QDIKSAARTN GRPDFVRLEQ QLHLKRSQLD FYARKYVPLI NARVREIIRS SWASAMKLTY 

       430        440        450        460        470        480 
EQVLLLIEAG QSQPPLQIWR EQSDDLPLSL AAALSDQPKR LANRTKGYDG ATIELCKRFD 

       490        500        510        520        530        540 
SHLADIVQEL NVMLQEQTTR AEDKVSLIEF LRETAEEQLT EYLSNLKGLE LRERPALLLA 

       550        560        570        580        590        600 
LRNSLALVEL CPNLKLCFCQ PSSWRQWTDN SAGLGIEHWQ RICGLIEKEM LSFWLVIVDD 

       610        620        630        640        650        660 
VLAGHNCEEK LPKVINHEVV LSDFALWQTL TLEQRDEDQE QSVQSTIRIP SQPRLSLQTY 

       670        680        690        700        710        720 
LHQLIQALNS VVPQTLPPKV LQAFIQRLIG KLLCHYEGLA HAECTKASQN IALQLYFDLK 

       730        740        750        760        770        780 
FLERVFAISR EERTLYDQIH AQQNQLRDYI DPFDFELFAE HITAHVSRAA SRLQGELGVL 

       790        800        810        820        830        840 
TPSAAAPSQG AAAASSLAHE ADPNVLCLSS SGSTSLWFPL LPIVMPQAAG RVTSAERKSP 

       850        860        870        880 
IQEPVEKTAT TTPTRKSGGN GARKGDSSKS KSSAASFFGM SQEWFR

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[2]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: Berkeley.
[3]"A Drosophila full-length cDNA resource."
Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A., Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M., Celniker S.E.
Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002) [PubMed: 12537569] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Berkeley.
Tissue: Head.
[4]"Phosphoproteome analysis of Drosophila melanogaster embryos."
Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.
J. Proteome Res. 7:1675-1682(2008) [PubMed: 18327897] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-839, MASS SPECTROMETRY.
Tissue: Embryo.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE014297 Genomic DNA. Translation: AAF54760.1.
AY058448 mRNA. Translation: AAL13677.1.
RefSeqNP_650162.1. NM_141905.2.
UniGeneDm.4266.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

DIPDIP-23267N.
IntActQ9VGC3. 1 interaction.
MINTMINT-861848.

Proteomic databases

PRIDEQ9VGC3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0082624; FBpp0082093; FBgn0037998.
GeneID41479.
KEGGdme:Dmel_CG4848.
NMPDRfig|7227.3.peg.12381.
UCSCCG4848-RA. d. melanogaster.

Organism-specific databases

FlyBaseFBgn0037998. CG4848.

Phylogenomic databases

eggNOGinNOG06806.
GeneTreeEMGT00050000010833.
InParanoidQ9VGC3.
OMAFLWSESP.
OrthoDBEOG4X95Z6.
PhylomeDBQ9VGC3.

Gene expression databases

ArrayExpressQ9VGC3.
BgeeQ9VGC3.
GermOnlineCG4848. Drosophila melanogaster.

Family and domain databases

InterProIPR014812. Vps51.
[Graphical view]
PfamPF08700. Vps51. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio824083.

Entry information

Entry nameCOG1_DROME
AccessionPrimary (citable) accession number: Q9VGC3
Entry history
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: May 1, 2000
Last modified: January 25, 2012
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Relevant documents

Drosophila

Drosophila: entries, gene names and cross-references to FlyBase

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents