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Protein
Submitted name:

Glutathione S transferase D10, isoform A

Gene

GstD10

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei9GlutathioneCombined sources1
Binding sitei39GlutathioneCombined sources1

GO - Molecular functioni

  • glutathione transferase activity Source: FlyBase

GO - Biological processi

  • glutathione metabolic process Source: FlyBase

Keywordsi

Molecular functionTransferaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Glutathione S transferase D10, isoform AImported (EC:2.5.1.18Imported)
Submitted name:
Glutathione S transferase D10, isoform BImported
Submitted name:
IP02193pImported
Submitted name:
IP02196pImported
Gene namesi
Name:GstD10Imported
ORF Names:CG18548Imported, Dmel_CG18548Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0042206. GstD10.

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiFBgn0042206.

Interactioni

Protein-protein interaction databases

MINTiMINT-1018146.
STRINGi7227.FBpp0082079.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3F6FX-ray1.60A1-210[»]
3GH6X-ray1.65A1-210[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 81GST N-terminalInterPro annotationAdd BLAST81
Domaini87 – 208GST C-terminalInterPro annotationAdd BLAST122

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni51 – 53Glutathione bindingCombined sources3
Regioni65 – 67Glutathione bindingCombined sources3

Sequence similaritiesi

Belongs to the GST superfamily.SAAS annotation

Phylogenomic databases

eggNOGiKOG0867. Eukaryota.
COG0625. LUCA.
GeneTreeiENSGT00540000069741.
KOiK00799.
OMAiHIMLEEC.
OrthoDBiEOG091G0MS3.

Family and domain databases

InterProiView protein in InterPro
IPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
PfamiView protein in Pfam
PF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiView protein in PROSITE
PS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9VGA1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLYYRPGSA PCRSVLMTAK ALGVEFDKKT IINTRAREQF TPEYLKINPQ
60 70 80 90 100
HTIPTLHDHG FALWESRAIM VYLVEKYGKD DKLFPKDVQK QALINQRLYF
110 120 130 140 150
DMGTLYKSFS EYYYPQIFLK KPANEENYKK IEVAFEFLNT FLEGQTYSAG
160 170 180 190 200
GDYSLADIAF LATVSTFDVA GFDFKRYANV ARWYENAKKL TPGWEENWAG
210
CQEFRKYFDN
Length:210
Mass (Da):24,593
Last modified:May 1, 2000 - v1
Checksum:iC47BB348D6AC34B3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAF54784.1.
BT025011 mRNA. Translation: ABE01241.1.
BT029403 mRNA. Translation: ABK57060.1.
AE014297 Genomic DNA. Translation: AHN57301.1.
RefSeqiNP_001287302.1. NM_001300373.1.
NP_652713.1. NM_144456.3.
UniGeneiDm.24889.

Genome annotation databases

EnsemblMetazoaiFBtr0082609; FBpp0082079; FBgn0042206.
FBtr0344264; FBpp0310669; FBgn0042206.
GeneIDi59240.
KEGGidme:Dmel_CG18548.
UCSCiCG18548-RA. d. melanogaster.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ9VGA1_DROME
AccessioniPrimary (citable) accession number: Q9VGA1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: July 5, 2017
This is version 145 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported