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Q9VGA1 (Q9VGA1_DROME) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 93. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesSubmitted name:
Glutathione S transferase D10 EMBL AAF54784.1
EC=2.5.1.18 EMBL AAF54784.1
Submitted name:
IP02193p EMBL ABE01241.1
Submitted name:
IP02196p EMBL ABK57060.1
Gene names
Name:GstD10 EMBL AAF54784.1 FlyBase FBgn0042206
ORF Names:Dmel_CG18548 EMBL AAF54784.1
OrganismDrosophila melanogaster (Fruit fly)
Taxonomic identifier7227 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length210 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the GST superfamily. RuleBase RU003494

Contains 1 GST C-terminal domain. SAAS SAAS017933

Contains 1 GST N-terminal domain. SAAS SAAS017933

Ontologies

Keywords
   Molecular functionTransferase EMBL AAF54784.1
   Technical term3D-structure PDB 3GH6 PDB 3F6F
Complete proteome
Reference proteome
Gene Ontology (GO)
   Molecular functionglutathione transferase activity

Inferred from direct assay. Source: FlyBase

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region51 – 533Glutathione binding PDB 3GH6
Region65 – 673Glutathione binding PDB 3GH6

Sites

Binding site91Glutathione PDB 3GH6
Binding site391Glutathione PDB 3GH6

Sequences

Sequence LengthMass (Da)Tools
Q9VGA1 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: C47BB348D6AC34B3

FASTA21024,593
        10         20         30         40         50         60 
MDLYYRPGSA PCRSVLMTAK ALGVEFDKKT IINTRAREQF TPEYLKINPQ HTIPTLHDHG 

        70         80         90        100        110        120 
FALWESRAIM VYLVEKYGKD DKLFPKDVQK QALINQRLYF DMGTLYKSFS EYYYPQIFLK 

       130        140        150        160        170        180 
KPANEENYKK IEVAFEFLNT FLEGQTYSAG GDYSLADIAF LATVSTFDVA GFDFKRYANV 

       190        200        210 
ARWYENAKKL TPGWEENWAG CQEFRKYFDN

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[2]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Berkeley.
[3]"Crystal Structure of Glutathione Transferase dmGSTD10 from Drosophila melanogaster."
Wongsantichon J., Robinson R.C., Ketterman A.J.
Submitted (MAR-2009) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.65 ANGSTROMS) IN COMPLEX WITH GLUTATHIONE.
[4]"Crystal Structure of Glutathione Transferase dmGSTD10 from Drosophila melanogaster."
Wongsantichon J., Robinson R.C., Ketterman A.J.
Submitted (NOV-2008) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS).
[5]Stapleton M., Carlson J., Chavez C., Frise E., George R., Pacleb J., Park S., Wan K., Yu C., Celniker S.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[6]Stapleton M., Carlson J., Frise E., Kapadia B., Park S., Wan K., Yu C., Celniker S.
Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE014297 Genomic DNA. Translation: AAF54784.1.
BT025011 mRNA. Translation: ABE01241.1.
BT029403 mRNA. Translation: ABK57060.1.
RefSeqNP_652713.1. NM_144456.2.
UniGeneDm.24889.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3F6FX-ray1.60A1-210[»]
3GH6X-ray1.65A1-210[»]
ProteinModelPortalQ9VGA1.
SMRQ9VGA1. Positions 1-209.
ModBaseSearch...

Protein-protein interaction databases

MINTMINT-1018146.
STRINGQ9VGA1.

Proteomic databases

PRIDEQ9VGA1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0082609; FBpp0082079; FBgn0042206.
GeneID59240.
KEGGdme:Dmel_CG18548.
UCSCCG18548-RA. d. melanogaster.

Organism-specific databases

CTD59240.
FlyBaseFBgn0042206. GstD10.

Phylogenomic databases

eggNOGinNOG09765.
GeneTreeEMGT00070000025677.
InParanoidQ9VGA1.
OMAFRKYFDN.
OrthoDBEOG441NTC.
PhylomeDBQ9VGA1.

Gene expression databases

ArrayExpressQ9VGA1.
BgeeQ9VGA1.

Family and domain databases

InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR017933. Glutathione_S_Trfase/Cl_chnl_C.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
Gene3DG3DSA:1.20.1050.10. GST_C_like. 1 hit.
G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
KOK00799.
PfamPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMSSF47616. GST_C_like. 1 hit.
SSF52833. Thiordxn-like_fd. 1 hit.
PROSITEPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio841731.

Entry information

Entry nameQ9VGA1_DROME
AccessionPrimary (citable) accession number: Q9VGA1
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: January 25, 2012
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info