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Protein

Metallothionein-3

Gene

MtnC

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein binds cations of several transition elements. Thought to be involved in metal ion homeostasis (By similarity).By similarity

GO - Molecular functioni

  • metal ion binding Source: FlyBase

GO - Biological processi

  • metal ion homeostasis Source: FlyBase
  • response to metal ion Source: FlyBase

Keywordsi

LigandCadmium, Copper, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Metallothionein-3
Short name:
MT-3
Alternative name(s):
Metallothionein C
Gene namesi
Name:MtnC
ORF Names:CG5097
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0038790. MtnC.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001973561 – 43Metallothionein-3Add BLAST43

Proteomic databases

PaxDbiQ9VDN2.
PRIDEiQ9VDN2.

Expressioni

Gene expression databases

BgeeiFBgn0038790.
ExpressionAtlasiQ9VDN2. differential.
GenevisibleiQ9VDN2. DM.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0083292.

Structurei

3D structure databases

ProteinModelPortaliQ9VDN2.
SMRiQ9VDN2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

All cysteine residues are arranged in C-X-C groups. These are thought to be the metal-binding sites in other metallothioneins.

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG4738. Eukaryota.
ENOG410Z9YK. LUCA.
InParanoidiQ9VDN2.
OrthoDBiEOG091G1AD9.
PhylomeDBiQ9VDN2.

Family and domain databases

InterProiView protein in InterPro
IPR000966. Metalthion_5.
PfamiView protein in Pfam
PF02067. Metallothio_5. 1 hit.
PRINTSiPR00872. MTDIPTERA.

Sequencei

Sequence statusi: Complete.

Q9VDN2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
MVCKGCGTNC KCQDTKCGDN CACNQDCKCV CKNGPKDQCC KSK
Length:43
Mass (Da):4,597
Last modified:May 1, 2000 - v1
Checksum:iE54E722B14E89DFE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAF55758.1.
RefSeqiNP_650882.1. NM_142625.2.
UniGeneiDm.27349.

Genome annotation databases

EnsemblMetazoaiFBtr0083884; FBpp0083292; FBgn0038790.
GeneIDi42416.
KEGGidme:Dmel_CG5097.

Similar proteinsi

Entry informationi

Entry nameiMT3_DROME
AccessioniPrimary (citable) accession number: Q9VDN2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: May 1, 2000
Last modified: July 5, 2017
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. Metallothioneins
    Classification of metallothioneins and list of entries
  3. SIMILARITY comments
    Index of protein domains and families