Unreviewed, UniProtKB/TrEMBL Q9VDF4 (Q9VDF4_DROME)

Names and origin

Protein names

Submitted name:
    Cortactin EMBL AAF55840.1
Submitted name:
    LD29964p EMBL AAK93198.1

Gene names

Name:	Cortactin EMBL AAF55840.1 FlyBase FBgn0025865
ORF Names:	CG3637 FlyBase FBgn0025865, Dmel_CG3637 EMBL AAF55840.1

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	559 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 SH3 domain. RuleBase RU003338V3

Ontologies

Keywords
Domain	SH3 domain RuleBase RU003338V3
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	border follicle cell migration Inferred from mutant phenotype. Source: FlyBase ovarian ring canal formation Inferred from mutant phenotype. Source: FlyBase regulation of cell shape Inferred from mutant phenotype. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VDF4-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 2B767BD3EFF1BCB2	FASTA	559	61,083
	10 20 30 40 50 60 MWKASAGHQI QATSAASAED DDWETDPDFV NDVSEQEQRW GSKTIDGSGR TAGTIDMDKL 70 80 90 100 110 120 REETEQADLD KKKQLLKDQN AGYGYGGKFG VEKDRMDKSA VGHDYQGKVG KHASQKDYSD 130 140 150 160 170 180 GFGGKFGVQE DRKDKSAVGW DHVEKVEKHA SQKDYATGFG GKFGVQSDRV DKSAVGWDHI 190 200 210 220 230 240 EKVEKHESQK DYSKGFGGKF GVQEDRKDKS AVGWDHKEAP QKHASQVDHK VKPVIEGAKP 250 260 270 280 290 300 SNLRAKFENL AKNSEEESRK RAEEQKRLRE AKDKRDREEA AKKTVAENTP RTSTEAPPPK 310 320 330 340 350 360 GSRAAIQTGR TGGIGNAISA FNQMQSPVSE TPPARKEPII IPKAQPVKIE LEAKEEPTAS 370 380 390 400 410 420 TTSAAVAPTP TVVPAREPET APVAKAAAPP PDVVPQIEVE TVDTPPRSEP QSPVYVPTPQ 430 440 450 460 470 480 PEVHAQVQVQ PEPQPQADPE PVVEEEPLYQ NQAEIKAASP LPPTNGTVSE AVAPSGTATV 490 500 510 520 530 540 PEEAIYANSD NLADYLEDTG IHAIALYDYQ AADDDEISFD PDDVITHIEK IDDGWWRGLC 550 KNRYGLFPAN YVQVVGQNS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Li P., Liao G., Miranda A., Mungall C.J., Nunoo J. , Pacleb J., Paragas V., Park S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAK93198.1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014297 Genomic DNA. Translation: AAF55840.1. AY051774 mRNA. Translation: AAK93198.1.
RefSeq	NP_524426.2.
UniGene	Dm.4483
3D structure databases
HSSP	HSSP built from PDB template 1JO8 based on UniProtKB P15891.
SMR	Q9VDF4. Positions 498-554.
ModBase	Search...
Proteomic databases
PRIDE	Q9VDF4.
Genome annotation databases
Ensembl	FBgn0025865. Drosophila melanogaster. [Contig view]
GeneID	42491.
KEGG	dme:Dmel_CG3637.
NMPDR	fig|7227.3.peg.13838.
Organism-specific databases
FlyBase	FBgn0025865. Cortactin.
Phylogenomic databases
OMA	Q9VDF4. GWWRGLC.
Gene expression databases
ArrayExpress	Q9VDF4.
Family and domain databases
InterPro	IPR003134. Hs1_Cortactin. IPR000108. Neu_cyt_fact_2. IPR001452. SH3_domain. [Graphical view]
Pfam	PF02218. HS1_rep. 4 hits. PF00018. SH3_1. 1 hit. [Graphical view]
PRINTS	PR00499. P67PHOX.
ProDom	PD000066. SH3. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00326. SH3. 1 hit. [Graphical view]
PROSITE	PS51090. CORTACTIN. 4 hits. PS50002. SH3. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	829065.

Entry information

Entry name

Q9VDF4_DROME

Accession

Primary (citable) accession number: Q9VDF4

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	June 16, 2009
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)