Unreviewed, UniProtKB/TrEMBL Q9VDC4 (Q9VDC4_DROME)

Names and origin

Protein names

Submitted name:
    ETHR, isoform A EMBL AAF55872.2
Submitted name:
    Putative ETH receptor splicing variant a EMBL AAO74886.1

Gene names

Name:	ETHR EMBL AAF55872.2 FlyBase FBgn0038874
ORF Names:	CG5911 FlyBase FBgn0038874, Dmel_CG5911 EMBL AAF55872.2

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	471 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the G-protein coupled receptor 1 family. RuleBase RU000688V2

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane RuleBase RU000688V2
Molecular function	G-protein coupled receptor RuleBase RU000688V2 Receptor Transducer
Gene Ontology (GO)
Biological process	G-protein coupled receptor protein signaling pathway Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular function	ecdysis-triggering hormone receptor activity Ref.3 Inferred from direct assay. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VDC4-1 [UniParc]. Last modified July 5, 2004. Version 2. Checksum: 719049EA24D66C23	FASTA	471	52,774
	10 20 30 40 50 60 MLPQIPSYIR TTAMFFCIVI MLLGVVGNVM VPIVIVKTKD MRNSTNIFLT NLSIADLLVL 70 80 90 100 110 120 LVCTPTVLVE VNTRPETWVL GHEMCKAVPF VELTVAHASV LTILAISFER YYAICEPLKA 130 140 150 160 170 180 GYVCTKGRAI LICVLAWGIA ALFTSPILWV AEYKLAEYID GSSVAVCLTQ AISDWTLAFF 190 200 210 220 230 240 LMTISVFFVV PFVTLVVLYG IIARNLVSNR AAMLRARPTK PELSLKARKQ VVLMLGAVVL 250 260 270 280 290 300 SFFVCLLPFR VLTLWIILST DQTLHDLGLV RYYSLLYFCR IMLYLNSAMN PILYNLMSTK 310 320 330 340 350 360 FRRGFKRLCQ DAGRLLLELV TLGRRKEDSS RGRRGTLSLG MGTNTNTNTN SSNATGATSS 370 380 390 400 410 420 SILSRSSNRR CSEDISRTRL KIEMQMPCGS DLEAMAMLQH STLGKGIARR VSDSRLMPLR 430 440 450 460 470 NHQPRRHKPQ ISFDEESLEE NKRSEAKIPT KCREKLPGIA REIVNLTENT L

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	"Two subtypes of ecdysis-triggering hormone receptor in Drosophila melanogaster." Park Y., Kim Y.J., Dupriez V., Adams M.E. J. Biol. Chem. 278:17710-17715(2003) [PubMed: 12586820] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: CantonS EMBL AAO74886.1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014297 Genomic DNA. Translation: AAF55872.2. AY220741 mRNA. Translation: AAO74886.1.
RefSeq	NP_650960.2.
UniGene	Dm.16652
3D structure databases
ModBase	Search...
Protein family/group databases
GPCRDB	Search...
Genome annotation databases
Ensembl	FBgn0038874. Drosophila melanogaster. [Contig view]
GeneID	42523.
KEGG	dme:Dmel_CG5911.
NMPDR	fig|7227.3.peg.13883.
Organism-specific databases
FlyBase	FBgn0038874. ETHR.
Phylogenomic databases
OMA	Q9VDC4. RIFCTIA.
Gene expression databases
ArrayExpress	Q9VDC4.
Family and domain databases
InterPro	IPR000276. 7TM_GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_supfam. IPR009144. Thyrotropin_RHR. [Graphical view]
Pfam	PF00001. 7tm_1. 1 hit. [Graphical view]
PRINTS	PR00237. GPCRRHODOPSN. PR01846. TRHRFAMILY.
PROSITE	PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	829250.

Entry information

Entry name

Q9VDC4_DROME

Accession

Primary (citable) accession number: Q9VDC4
Secondary accession number(s): Q86C63

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	July 5, 2004
Last modified:	June 16, 2009
This is version 55 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)