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Q9VD23 (Q9VD23_DROME) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 106. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length744 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + pyruvate = ADP + phosphoenolpyruvate. RuleBase RU000504

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5. RuleBase RU000504

Sequence similarities

Belongs to the pyruvate kinase family. RuleBase RU000504

Ontologies

Keywords
   Biological processGlycolysis RuleBase RU000504
   LigandMagnesium RuleBase RU000504
   Molecular functionKinase RuleBase RU000504
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: InterPro

potassium ion binding

Inferred from electronic annotation. Source: InterPro

pyruvate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q9VD23 [UniParc].

Last modified March 1, 2001. Version 2.
Checksum: 27AAD998D07E17B7

FASTA74483,997
        10         20         30         40         50         60 
MRVVRMNFSH GSHEYHCQTI QAARKAIAMY VEQTGLPRTL AIALDTKGPE IRTGKLAGGN 

        70         80         90        100        110        120 
DRAEIELKTG DKVTLSTKKE MADKSNKDNI YVDYQRLPQL VKPGNRVFVD DGLIALIVKE 

       130        140        150        160        170        180 
SKGDEVICQV ENGGKLGSHK GINLPGVPVD LPSVTEKDKQ DLKFGAEQKV DMIFASFIRD 

       190        200        210        220        230        240 
ANALKEIRQV LGPAGACIKI ISKIENHQGL VNIDDIIRES DGIMVARGDM GIEIPTEDVP 

       250        260        270        280        290        300 
LAQKSIVAKC NKVGKPVICA TQMMESMTNK PRPTRAEASD VANAIFDGCD AVMLSGETAK 

       310        320        330        340        350        360 
GKYPVECVQC MARICAKVEA VLWYESLQNS LKREIRTSAA DHISAVTTAI AEAATVGQAR 

       370        380        390        400        410        420 
AIVVASPCSM VAQMVSHMRP PCPIVMLTGN ESEAAQSLLF RGIYPLLVEE MVIGSFNFRR 

       430        440        450        460        470        480 
IMQSGLKLMG KMDILEPGQK GSVVLVNAMS AEKITFRLFT IRQQTKEERD QDERCRKLAL 

       490        500        510        520        530        540 
EQSCKERAEK EECRKLQQAE ECQKQKLAKK CKQFEEKQKV CPKKNDTPKN DCPKKDCPKK 

       550        560        570        580        590        600 
ECPKQDDEIS KCRQMQEAEA EERKCKEEFE QMCKLAEEKR KEAEKCRKAD EERRKEEAEK 

       610        620        630        640        650        660 
CRKLEEDRKC KLAEEKKRNE EELKIIEAEV AKLEAAEKAK RLKEEEKKKE ELMKCKQRNE 

       670        680        690        700        710        720 
AKKKREEAER CKRKEREREL AEMENKWKQV AEKRKRKKAA EMCRKIEDAK EKAAAESADK 

       730        740 
ILKAVCEKLK QSLSDPDKSK KGKK

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[2]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: Berkeley.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE014297 Genomic DNA. Translation: AAF55980.2.
RefSeqNP_651030.1. NM_142773.1.
UniGeneDm.14821.

3D structure databases

HSSPHSSP built from PDB template 1E0T based on UniProtKB P14178.
ProteinModelPortalQ9VD23.
SMRQ9VD23. Positions 1-444.
ModBaseSearch...

Protein-protein interaction databases

IntActQ9VD23. 1 interaction.
MINTMINT-764253.
STRINGQ9VD23.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0084215; FBpp0083612; FBgn0038952.
GeneID42621.
KEGGdme:Dmel_CG7069.
UCSCCG7069-RA. d. melanogaster.

Organism-specific databases

FlyBaseFBgn0038952. CG7069.

Phylogenomic databases

GeneTreeENSGT00390000008859.
InParanoidQ9VD23.
KOK00873.
OrthoDBEOG4HMGRF.
PhylomeDBQ9VD23.

Enzyme and pathway databases

UniPathwayUPA00109; UER00188.

Gene expression databases

ArrayExpressQ9VD23.
BgeeQ9VD23.

Family and domain databases

Gene3D2.40.33.10. 1 hit.
3.20.20.60. 2 hits.
3.40.1380.20. 1 hit.
InterProIPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase.
IPR011037. Pyrv_Knase-like_insert_dom.
IPR015794. Pyrv_Knase_a/b.
IPR018209. Pyrv_Knase_AS.
IPR015793. Pyrv_Knase_brl.
IPR015795. Pyrv_Knase_C.
IPR015806. Pyrv_Knase_insert_dom.
[Graphical view]
PANTHERPTHR11817. PTHR11817. 1 hit.
PfamPF00224. PK. 1 hit.
PF02887. PK_C. 1 hit.
[Graphical view]
PRINTSPR01050. PYRUVTKNASE.
SUPFAMSSF50800. PK_B_barrel_like. 1 hit.
SSF52935. Pyruvate_kinase. 1 hit.
SSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
TIGRFAMsTIGR01064. pyruv_kin. 1 hit.
PROSITEPS00110. PYRUVATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi42621.
NextBio829736.

Entry information

Entry nameQ9VD23_DROME
AccessionPrimary (citable) accession number: Q9VD23
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: March 1, 2001
Last modified: May 1, 2013
This is version 106 of the entry and version 2 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info