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Q9VD23 (Q9VD23_DROME) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 114. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length744 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + pyruvate = ADP + phosphoenolpyruvate. RuleBase RU000504

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5. RuleBase RU000504

Sequence similarities

Belongs to the pyruvate kinase family. RuleBase RU000504

Ontologies

Sequences

Sequence LengthMass (Da)Tools
Q9VD23 [UniParc].

Last modified March 1, 2001. Version 2.
Checksum: 27AAD998D07E17B7

FASTA74483,997
        10         20         30         40         50         60 
MRVVRMNFSH GSHEYHCQTI QAARKAIAMY VEQTGLPRTL AIALDTKGPE IRTGKLAGGN 

        70         80         90        100        110        120 
DRAEIELKTG DKVTLSTKKE MADKSNKDNI YVDYQRLPQL VKPGNRVFVD DGLIALIVKE 

       130        140        150        160        170        180 
SKGDEVICQV ENGGKLGSHK GINLPGVPVD LPSVTEKDKQ DLKFGAEQKV DMIFASFIRD 

       190        200        210        220        230        240 
ANALKEIRQV LGPAGACIKI ISKIENHQGL VNIDDIIRES DGIMVARGDM GIEIPTEDVP 

       250        260        270        280        290        300 
LAQKSIVAKC NKVGKPVICA TQMMESMTNK PRPTRAEASD VANAIFDGCD AVMLSGETAK 

       310        320        330        340        350        360 
GKYPVECVQC MARICAKVEA VLWYESLQNS LKREIRTSAA DHISAVTTAI AEAATVGQAR 

       370        380        390        400        410        420 
AIVVASPCSM VAQMVSHMRP PCPIVMLTGN ESEAAQSLLF RGIYPLLVEE MVIGSFNFRR 

       430        440        450        460        470        480 
IMQSGLKLMG KMDILEPGQK GSVVLVNAMS AEKITFRLFT IRQQTKEERD QDERCRKLAL 

       490        500        510        520        530        540 
EQSCKERAEK EECRKLQQAE ECQKQKLAKK CKQFEEKQKV CPKKNDTPKN DCPKKDCPKK 

       550        560        570        580        590        600 
ECPKQDDEIS KCRQMQEAEA EERKCKEEFE QMCKLAEEKR KEAEKCRKAD EERRKEEAEK 

       610        620        630        640        650        660 
CRKLEEDRKC KLAEEKKRNE EELKIIEAEV AKLEAAEKAK RLKEEEKKKE ELMKCKQRNE 

       670        680        690        700        710        720 
AKKKREEAER CKRKEREREL AEMENKWKQV AEKRKRKKAA EMCRKIEDAK EKAAAESADK 

       730        740 
ILKAVCEKLK QSLSDPDKSK KGKK 

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[2]"Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence."
Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., Pacleb J.M., Park S. expand/collapse author list , Pfeiffer B.D., Richards S., Sodergren E.J., Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.
Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[3]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: Berkeley.
[4]"The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective."
Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M., Celniker S.E.
Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[5]"Heterochromatic sequences in a Drosophila whole-genome shotgun assembly."
Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., Karpen G.H.
Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[6]"Combined evidence annotation of transposable elements in genome sequences."
Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., Ashburner M., Anxolabehere D.
PLoS Comput. Biol. 1:166-175(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[7]"The Release 5.1 annotation of Drosophila melanogaster heterochromatin."
Smith C.D., Shu S., Mungall C.J., Karpen G.H.
Science 316:1586-1591(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[8]"Sequence finishing and mapping of Drosophila melanogaster heterochromatin."
Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., Dimitri P., Karpen G.H., Celniker S.E.
Science 316:1625-1628(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014297 Genomic DNA. Translation: AAF55980.2.
RefSeqNP_651030.1. NM_142773.1.
UniGeneDm.14821.

3D structure databases

ProteinModelPortalQ9VD23.
SMRQ9VD23. Positions 1-444.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ9VD23. 1 interaction.
MINTMINT-764253.

Proteomic databases

PRIDEQ9VD23.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0084215; FBpp0083612; FBgn0038952.
GeneID42621.
KEGGdme:Dmel_CG7069.
UCSCCG7069-RA. d. melanogaster.

Organism-specific databases

FlyBaseFBgn0038952. CG7069.

Phylogenomic databases

GeneTreeENSGT00390000008859.
InParanoidQ9VD23.
KOK00873.
OMAVICQVEN.
OrthoDBEOG78M01Q.
PhylomeDBQ9VD23.

Enzyme and pathway databases

UniPathwayUPA00109; UER00188.

Gene expression databases

BgeeQ9VD23.

Family and domain databases

Gene3D2.40.33.10. 1 hit.
3.20.20.60. 2 hits.
3.40.1380.20. 1 hit.
InterProIPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR011037. Pyrv_Knase-like_insert_dom.
IPR015794. Pyrv_Knase_a/b.
IPR018209. Pyrv_Knase_AS.
IPR015793. Pyrv_Knase_brl.
IPR015795. Pyrv_Knase_C.
IPR015806. Pyrv_Knase_insert_dom.
[Graphical view]
PANTHERPTHR11817. PTHR11817. 1 hit.
PfamPF00224. PK. 1 hit.
PF02887. PK_C. 1 hit.
[Graphical view]
PRINTSPR01050. PYRUVTKNASE.
SUPFAMSSF50800. SSF50800. 1 hit.
SSF51621. SSF51621. 2 hits.
SSF52935. SSF52935. 1 hit.
TIGRFAMsTIGR01064. pyruv_kin. 1 hit.
PROSITEPS00110. PYRUVATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi42621.
NextBio829736.

Entry information

Entry nameQ9VD23_DROME
AccessionPrimary (citable) accession number: Q9VD23
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: March 1, 2001
Last modified: June 11, 2014
This is version 114 of the entry and version 2 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)