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Protein
Submitted name:

Uncharacterized protein

Gene

CG10177

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

  • cellular response to glucose starvation Source: GO_Central
  • Golgi organization Source: FlyBase
  • intracellular signal transduction Source: GO_Central
  • negative regulation of cell size Source: FlyBase
  • negative regulation of TOR signaling Source: GO_Central
  • protein phosphorylation Source: FlyBase
  • regulation of glucose metabolic process Source: FlyBase
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseSAAS annotation, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DME-381070. IRE1alpha activates chaperones.
SignaLinkiQ9VCL7.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported (EC:2.7.11.-Imported)
Gene namesi
ORF Names:CG10177Imported, Dmel_CG10177Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0039083. CG10177.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ9VCL7.
PRIDEiQ9VCL7.

Expressioni

Gene expression databases

BgeeiFBgn0039083.
GenevisibleiQ9VCL7. DM.

Interactioni

Protein-protein interaction databases

IntActiQ9VCL7. 1 interactor.
MINTiMINT-1655857.
STRINGi7227.FBpp0083816.

Structurei

3D structure databases

ProteinModelPortaliQ9VCL7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 108DoublecortinInterPro annotationAdd BLAST87
Domaini149 – 409Protein kinaseInterPro annotationAdd BLAST261

Phylogenomic databases

eggNOGiKOG0032. Eukaryota.
ENOG410XRMJ. LUCA.
GeneTreeiENSGT00390000015684.
InParanoidiQ9VCL7.
OMAiDIVVCCC.
OrthoDBiEOG091G0AX6.
PhylomeDBiQ9VCL7.

Family and domain databases

CDDicd01617. DCX. 1 hit.
Gene3Di3.10.20.230. 1 hit.
InterProiIPR020636. Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR003533. Doublecortin_dom.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PANTHERiPTHR24347. PTHR24347. 1 hit.
PfamiPF03607. DCX. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00537. DCX. 1 hit.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50309. DC. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9VCL7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEQSTSLGS RRVGPPLHKK ALRVCFLRNG DRHFKGVNLV ISRAHFKDFP
60 70 80 90 100
ALLQGVTESL KRHVLLRSAI AHFRRTDGSH LTSLSCFRET DIVICCCKNE
110 120 130 140 150
EIICVKYSIN KDFQRMVDSC KRWGQHHLDS GTLESMKSHD LPEAIQLYIE
160 170 180 190 200
TIEPVEHNTR TLIYRGQTRA NRTKCTVKMV NKQTQSNDRG DTYMEAEVLR
210 220 230 240 250
QLQSHPNIIE LMYTVEDERY MYTVLEHLDC NMQKVIQKRG ILSEADARSV
260 270 280 290 300
MRCTVSALAH MHQLQVIHRD IKPENLLVCS SSGKWNFKMV KVANFDLATY
310 320 330 340 350
YRGSKLYVRC GTPCYMAPEM IAMSGYDYQV DSWSLGVTLF YMLCGKMPFA
360 370 380 390 400
SACKNSKEIY AAIMSGGPTY PKDMESVMSP EATQLIDGLL VSDPSYRVPI
410
AELDKFQFLA L
Length:411
Mass (Da):46,927
Last modified:May 1, 2000 - v1
Checksum:i5C5969F51FE52D6A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAF56141.1.
RefSeqiNP_651150.1. NM_142893.2.
UniGeneiDm.13330.

Genome annotation databases

EnsemblMetazoaiFBtr0084424; FBpp0083816; FBgn0039083.
GeneIDi42772.
KEGGidme:Dmel_CG10177.
UCSCiCG10177-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAF56141.1.
RefSeqiNP_651150.1. NM_142893.2.
UniGeneiDm.13330.

3D structure databases

ProteinModelPortaliQ9VCL7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9VCL7. 1 interactor.
MINTiMINT-1655857.
STRINGi7227.FBpp0083816.

Proteomic databases

PaxDbiQ9VCL7.
PRIDEiQ9VCL7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0084424; FBpp0083816; FBgn0039083.
GeneIDi42772.
KEGGidme:Dmel_CG10177.
UCSCiCG10177-RA. d. melanogaster.

Organism-specific databases

FlyBaseiFBgn0039083. CG10177.

Phylogenomic databases

eggNOGiKOG0032. Eukaryota.
ENOG410XRMJ. LUCA.
GeneTreeiENSGT00390000015684.
InParanoidiQ9VCL7.
OMAiDIVVCCC.
OrthoDBiEOG091G0AX6.
PhylomeDBiQ9VCL7.

Enzyme and pathway databases

ReactomeiR-DME-381070. IRE1alpha activates chaperones.
SignaLinkiQ9VCL7.

Miscellaneous databases

GenomeRNAii42772.

Gene expression databases

BgeeiFBgn0039083.
GenevisibleiQ9VCL7. DM.

Family and domain databases

CDDicd01617. DCX. 1 hit.
Gene3Di3.10.20.230. 1 hit.
InterProiIPR020636. Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR003533. Doublecortin_dom.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PANTHERiPTHR24347. PTHR24347. 1 hit.
PfamiPF03607. DCX. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00537. DCX. 1 hit.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50309. DC. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9VCL7_DROME
AccessioniPrimary (citable) accession number: Q9VCL7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 144 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.