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Q9VCE9

- UBS3A_DROME

UniProt

Q9VCE9 - UBS3A_DROME

Protein

Protein UBASH3A homolog

Gene

CG13604

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 106 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. catalytic activity Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein UBASH3A homolog
    Gene namesi
    ORF Names:CG13604
    OrganismiDrosophila melanogaster (Fruit fly)
    Taxonomic identifieri7227 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000000803: Chromosome 3R

    Organism-specific databases

    FlyBaseiFBgn0039137. CG13604.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 751751Protein UBASH3A homologPRO_0000210995Add
    BLAST

    Proteomic databases

    PaxDbiQ9VCE9.
    PRIDEiQ9VCE9.

    Expressioni

    Gene expression databases

    BgeeiQ9VCE9.

    Interactioni

    Protein-protein interaction databases

    BioGridi67775. 4 interactions.
    DIPiDIP-21366N.
    IntActiQ9VCE9. 1 interaction.
    MINTiMINT-341393.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9VCE9.
    SMRiQ9VCE9. Positions 18-68, 266-343, 492-745.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini16 – 6045UBAPROSITE-ProRule annotationAdd
    BLAST
    Domaini271 – 33666SH3PROSITE-ProRule annotationAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni490 – 751262Phosphatase-likeAdd
    BLAST

    Sequence similaritiesi

    Contains 1 SH3 domain.PROSITE-ProRule annotation
    Contains 1 UBA domain.PROSITE-ProRule annotation

    Keywords - Domaini

    SH3 domain

    Phylogenomic databases

    eggNOGiNOG276661.
    GeneTreeiENSGT00390000018249.
    InParanoidiQ9VCE9.
    OrthoDBiEOG7P5T0D.
    PhylomeDBiQ9VCE9.

    Family and domain databases

    Gene3Di3.40.50.1240. 3 hits.
    3.90.1140.10. 1 hit.
    InterProiIPR013078. His_Pase_superF_clade-1.
    IPR029033. His_PPase_superfam.
    IPR009097. RNA_ligase/cNuc_Pdiesterase.
    IPR001452. SH3_domain.
    IPR009060. UBA-like.
    IPR015940. UBA/transl_elong_EF1B_N_euk.
    IPR000449. UBA/Ts_N.
    [Graphical view]
    PfamiPF00300. His_Phos_1. 1 hit.
    PF14604. SH3_9. 1 hit.
    PF00627. UBA. 1 hit.
    [Graphical view]
    SMARTiSM00855. PGAM. 1 hit.
    SM00326. SH3. 1 hit.
    SM00165. UBA. 1 hit.
    [Graphical view]
    SUPFAMiSSF46934. SSF46934. 1 hit.
    SSF50044. SSF50044. 1 hit.
    SSF53254. SSF53254. 2 hits.
    PROSITEiPS50002. SH3. 1 hit.
    PS50030. UBA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9VCE9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MATLPPRKSQ TPTRICISKQ HLTPLQTLLQ MGFPRHRAEK ALASTGNRGV    50
    QIASDWLLAH VNDGTLDECA PREYIIYACP TGPFLQQLEE FWAKSRQMCG 100
    WNGAHNYVPH ITLVSFFKAP DECSLQLSKA LKQVVDMTGA LLDRPLKLEP 150
    YMSQNFMGFF VAEEDANYLK RLALQYVKEV SNSIISDTYE QLDAIVACFP 200
    WCGAVSSGTR CIPRSSRSIS LEPHVKSLHL TLAYQFPQAQ FNALKALVET 250
    LDASCASNWE LRLYSRDPRL ATKQVQKVVY PHNPHETDEL ELRIGDYIYL 300
    NTEVVDSSSD GWAEGISWLT GSTGHLPVNY TERTAESDAW TLHRVVQLSK 350
    SVASSLTSAE DLDIVDGRSI STEPDDRQNT AHPDIIEGSS FEESEQSVEK 400
    YLRQTLKPCL ELPSVQLLNS HNLTHQHNPN TPTIEITTNM SSSSTSMSKQ 450
    PVDEILVEPP AAQPPRPDDT LSVHSDHSLH PGSLDASHAK NRKIYIMRHG 500
    ERVDFTFGTW IPYCFDEFGN YMRKDLNMPK TLPRRKNSPE GWQNDSPLTN 550
    VGVYQANLIG QALLEAQVQI DHVYCSPSYR CIQTCTSALE GLKLTGKQKI 600
    KLEPGLFEWM AWYPSGVPDW LTKNELTEAK FDVDLDYEPV QPASELTARL 650
    KESTEQFYER NHDVILQLLE QTTGNILVVA HATTLDTCSR QLTGGVPRST 700
    NELRQVIHKI PYCSLATVEQ VDGVWKLVEP ECLPVTHSKN PRFEWNALSA 750
    T 751
    Length:751
    Mass (Da):84,466
    Last modified:May 1, 2000 - v1
    Checksum:iFF893BB3FEDFDB2D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014297 Genomic DNA. Translation: AAF56217.1.
    AY051411 mRNA. Translation: AAK92835.1.
    RefSeqiNP_651202.1. NM_142945.3.
    UniGeneiDm.4624.

    Genome annotation databases

    EnsemblMetazoaiFBtr0084509; FBpp0083896; FBgn0039137.
    GeneIDi42840.
    KEGGidme:Dmel_CG13604.
    UCSCiCG13604-RA. d. melanogaster.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014297 Genomic DNA. Translation: AAF56217.1 .
    AY051411 mRNA. Translation: AAK92835.1 .
    RefSeqi NP_651202.1. NM_142945.3.
    UniGenei Dm.4624.

    3D structure databases

    ProteinModelPortali Q9VCE9.
    SMRi Q9VCE9. Positions 18-68, 266-343, 492-745.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 67775. 4 interactions.
    DIPi DIP-21366N.
    IntActi Q9VCE9. 1 interaction.
    MINTi MINT-341393.

    Proteomic databases

    PaxDbi Q9VCE9.
    PRIDEi Q9VCE9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0084509 ; FBpp0083896 ; FBgn0039137 .
    GeneIDi 42840.
    KEGGi dme:Dmel_CG13604.
    UCSCi CG13604-RA. d. melanogaster.

    Organism-specific databases

    FlyBasei FBgn0039137. CG13604.

    Phylogenomic databases

    eggNOGi NOG276661.
    GeneTreei ENSGT00390000018249.
    InParanoidi Q9VCE9.
    OrthoDBi EOG7P5T0D.
    PhylomeDBi Q9VCE9.

    Miscellaneous databases

    GenomeRNAii 42840.
    NextBioi 830850.
    PROi Q9VCE9.

    Gene expression databases

    Bgeei Q9VCE9.

    Family and domain databases

    Gene3Di 3.40.50.1240. 3 hits.
    3.90.1140.10. 1 hit.
    InterProi IPR013078. His_Pase_superF_clade-1.
    IPR029033. His_PPase_superfam.
    IPR009097. RNA_ligase/cNuc_Pdiesterase.
    IPR001452. SH3_domain.
    IPR009060. UBA-like.
    IPR015940. UBA/transl_elong_EF1B_N_euk.
    IPR000449. UBA/Ts_N.
    [Graphical view ]
    Pfami PF00300. His_Phos_1. 1 hit.
    PF14604. SH3_9. 1 hit.
    PF00627. UBA. 1 hit.
    [Graphical view ]
    SMARTi SM00855. PGAM. 1 hit.
    SM00326. SH3. 1 hit.
    SM00165. UBA. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46934. SSF46934. 1 hit.
    SSF50044. SSF50044. 1 hit.
    SSF53254. SSF53254. 2 hits.
    PROSITEi PS50002. SH3. 1 hit.
    PS50030. UBA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Drosophila melanogaster."
      Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
      , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
      Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Berkeley.
    2. Cited for: GENOME REANNOTATION.
      Strain: Berkeley.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: Berkeley.
      Tissue: Head.

    Entry informationi

    Entry nameiUBS3A_DROME
    AccessioniPrimary (citable) accession number: Q9VCE9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 106 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programDrosophila annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Drosophila
      Drosophila: entries, gene names and cross-references to FlyBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3