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Protein

Palmitoyltransferase

Gene

CG17198

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
ORF Names:CG17198Imported, Dmel_CG17198Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0039366. CG17198.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei35 – 54HelicalUniRule annotationAdd BLAST20
Transmembranei66 – 84HelicalUniRule annotationAdd BLAST19
Transmembranei160 – 177HelicalUniRule annotationAdd BLAST18
Transmembranei214 – 237HelicalUniRule annotationAdd BLAST24

GO - Cellular componenti

  • endoplasmic reticulum Source: FlyBase
  • integral component of membrane Source: UniProtKB-KW

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0084298.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini115 – 250DHHCInterPro annotationAdd BLAST136

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1311. Eukaryota.
COG5273. LUCA.
GeneTreeiENSGT00850000132405.
KOiK18932.
OMAiTTWIVYN.
OrthoDBiEOG091G0RWR.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. DHHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9VBM8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKISHVFVQL RGIMQSQVQM QTINIPRRVG AIKSWTDIMG VSINVCIILF
60 70 80 90 100
FYFFEAFYVM PQFLGLFGQA VHFLVTTWIV YNILENLRLC VTTLNTVDSL
110 120 130 140 150
PPQMQQPMKG EEHLWHFCKI CQRNVPPRSW HCNICDACIL KRDHHCNFVG
160 170 180 190 200
NCVGHNNQRY FIWFSFYAAI GSAVALFDNF MLAHKHGVGF FDLVKANYII
210 220 230 240 250
FNAYMNPGRK ELVIFYRIVS VLGVNIFAVL FPAALFCTQV VTVIKNSVMH
260 270 280 290
DYSDRTYDLG LGNNLTLILG SRRLWTCLSP NIKSPLPHNG TRWKSKRAV
Length:299
Mass (Da):34,423
Last modified:February 7, 2006 - v3
Checksum:i58F5A2B43E91DCA0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAF56502.3.
BT022182 mRNA. Translation: AAY51576.1.
AE014297 Genomic DNA. Translation: AHN57531.1.
RefSeqiNP_001287532.1. NM_001300603.1.
NP_651424.3. NM_143167.2.
UniGeneiDm.31345.

Genome annotation databases

EnsemblMetazoaiFBtr0084924; FBpp0084298; FBgn0039366.
FBtr0344619; FBpp0310940; FBgn0039366.
GeneIDi43110.
KEGGidme:Dmel_CG17198.
UCSCiCG17198-RA. d. melanogaster.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ9VBM8_DROME
AccessioniPrimary (citable) accession number: Q9VBM8
Secondary accession number(s): Q4V6X4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: February 7, 2006
Last modified: July 5, 2017
This is version 129 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported